BEAS-2B Cells
High basal expression of interferon stimulated genes in human bronchial epithelial (BEAS 2B) cells contributes to influenza A virus resistance
... NHBE cells with human IAVs growing to higher titres ...that BEAS-2B cells were relatively more resistant to human H1N1 than avian H2N3 influenza virus ...that BEAS-2B ...
10
LPS Induced Proliferation and Chemokine Secretion from BEAS 2B Cells
... In BEAS-2B cells, LPS on the one hand up-regulate ERK 1/2, p38 and JNK MAPK, and, on the other hand lead to increased cell proliferation and secretion of ...stimulated cells, we proved the ...
12
Poly (I:C), an agonist of toll like receptor 3, inhibits replication of the Chikungunya virus in BEAS 2B cells
... Based on the results of the present study, we conclude that both Poly (I:C) and CHIKV infection enhanced the expression of TLR3. The stimulation of TLR3 by dsRNA transduces signals to activate the transcription factors ...
8
Endocytic Markers Associated with the Internalization and Processing of Aspergillus fumigatus Conidia by BEAS-2B Cells
... epithelial cells make up a significant portion of the pulmonary-air inter- face, we set out to determine the percentage of conidia that are actually internal- ized after initial contact with airway epithelial ...by ...
21
Aeroallergen Der p 2 induces apoptosis of bronchial epithelial BEAS-2B cells via activation of both intrinsic and extrinsic pathway
... ROS is commonly assumed as an important stress factor involving in pathogenesis of allergic airway diseases and activation of mitochondrial pathway [13]. To investigate whether rDP2 induced ROS, intracellular ROS level ...
11
Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration
... We previously demonstrated that XB130 binds specifically to Tks5’s fifth SH3 domain endogenously, to regulate cell proliferation and survival in BEAS-2B cells [16]. In this study, the inhibition of ...
16
In vitro invasive ability of X and V factor dependent Haemophilus species across different cell types
... epithelial cells in vitro, and it has been suggested that this may be a virulence attribute, particularly in persistent infections where the intracellular environment would protect the bacterial cells from ...
80
Strand-Specific Dual RNA Sequencing of Bronchial Epithelial Cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions
... of BEAS-2B cells infected with seasonal H3N2 ...epithelial cells to UD/72 infection have been reported ...in BEAS-2B cells infected with seasonal or laboratory strains ...
25
Environmentally persistent free radicals amplify ultrafine particle mediated cellular oxidative stress and cytotoxicity
... from BEAS-2B ...of cells to ultrafine particles resulted in diminished IL-10 and VEGF ...exposed cells might be the cause of the increased cell- death among particle exposed cells ...
14
Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival
... A549 cells, which are tumor-derived alveolar epithelial cells, and BEAS-2B cells, which are immortalized human bronchial epithelial cells, have altered survival and apoptotic ...
9
Dimerized translationally controlled tumor protein increases interleukin-8 expression through MAPK and NF-κB pathways in a human bronchial epithelial cell line
... to cells are very similar except for some points because they act through essentially the same receptor ...and BEAS-2B [6] cell lines that do not express detectable FcεRIα (see Additional file 2: ...
15
Modulation of airway epithelial cell functions by Pidotimod: NF-kB cytoplasmatic expression and its nuclear translocation are associated with an increased TLR-2 expression
... on BEAS-2B cells, stimulation of ERK1/2 phosphorylation by cysteinyl leukotriene D4 resulted in an increased ICAM-1 expre- ssion by 16HBE bronchial epithelial cells, associated with enhanced ...
9
Rhinovirus infection induces cytotoxicity and delays wound healing in bronchial epithelial cells
... exposed cells [15]; biopsy data show that in human RV infection epithelial inflam- mation, potentially resulting from infection, is patchy [27,36]: there has been, however, no direct comparison between normal and ...
11
OTU deubiquitinase 4 is silenced and radiosensitizes non-small cell lung cancer cells via inhibiting DNA repair
... First, the expression of OTUD4 in non-small cell lung cancer was analyzed. OTUD4 was dramatically down- regulated in NSCLC cell lines (Fig. 1a, b) and tumor tissues (Fig. 1c, d) compared with the lung bronchus epithelial ...
12
TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells
... that BEAS-2B cells ex- press TWEAK receptor Fn14 ...on BEAS-2B cells (Additional file 1: Figure ...in BEAS-2B cells. Confluent monolayers of ...
15
Cytokine responses of human lung cells (BEAS-2B) treated with micron-sized and nanoparticles of metal oxides compared to soil dusts
... of BEAS-2B cells treated with all the pure oxide particle types is low com- pared to the response to both the positive controls and some samples of soil-derived dust, a ubiquitous pollutant that is ...
18
Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth
... epithelial BEAS-2B (BEAS-2B) cells were transformed into arsenic-transformed cells (As-T) by exposing BEAS-2B cells to 1 µM sodium arsenic for 26 weeks as we ...
10
Cigarette smoke exposure enhances transforming acidic coiled-coil–containing protein 2 turnover and thereby promotes emphysema
... lial cells (pHAECs) were cultured with or without 2% CSE for 24 ...HBEC2 cells (immortalized by stable transduction with TERT, a catalytic subunit of telomerase and cyclin-dependent kinase 4; ...TACC2, ...
20
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway
... Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. (-)-Epigallocatechin-3-gallate (EGCG), a major polyphenol in green tea, is widely studied as a cancer chemopreventive agent with potential ...
10
Role of human rhinovirus in triggering human airway epithelial-mesenchymal transition
... in BEAS-2B cells, we used the pharmacological inhibitors SB203580 and PD98059 to inhibit the p38 and ERK 1/2 MAPK pathways, ...in BEAS- 2B did not begin to be observed until 48 h after ...
16