Beta-2 agonist.
Impact of extrafine formulations of inhaled corticosteroids/long-acting beta-2 agonist combinations on patient-related outcomes in asthma and COPD
... Abstract: Asthma and chronic obstructive pulmonary disease (COPD) are among the most common chronic diseases worldwide, characterized by a condition of variable degree of airway obstruction and chronic airway ...
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Inhaled beta 2 agonist salbutamol and acute lung injury: an association with improvement in acute lung injury
... β 2 ago- nist, aerosolized metaproterenol (5 mg), not only decreases high airway resistance and improves oxygenation, but also increases static compliance in human ...β 2 agonists in ALI because of a ...
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Risk of pneumonia with inhaled corticosteroid/long-acting β2 agonist therapy in chronic obstructive pulmonary disease: a cluster analysis
... Cluster analysis of two replicate one-year studies of FF/VI versus vilanterol identified five clusters of patients with differing risks for occurrence of pneumonia or serious pneumonia. Using the cluster with the lowest ...
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Clinical role of dual bronchodilation with an indacaterol–glycopyrronium combination in the management of COPD: its impact on patient-related outcomes and quality of life
... the beta 2 -agonist, and thereby amplify the bronchodilation elicited by the same beta 2 -agonist through direct stimulation of beta 2 -adrenoceptors in smooth ...
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Trend of cost and utilization of COPD medication in Korea
... systemic beta ago- nists were most widely prescribed between 2008 and ...long-acting beta-2 agonist (LABA), long-acting muscarinic agonist, and inhaled corticosteroid plus LABA were ...
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The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease
... The mechanism by which ICS/LABA combination reduces total mortality in COPD is uncertain. It is now well recognized that COPD is an inflammatory disorder, characterized by persistent lung and systemic inflamma- tion, ...
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Functional imaging using computer methods to compare the effect of salbutamol and ipratropium bromide in patient-specific airway models of COPD
... Using functional imaging, we demonstrated that central but mainly distal airway dimensions (third to seventh bifurcation) increased significantly after an inhaled beta 2 -agonist (salbutamol) and ...
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Do beta –2 Agonists reduce Admission rate in children with bronchiolitis?
... of beta-2 agonist in children with bronchiolitis and they did not find any true benefits of beta-2 agonists and they did not encourage the routine use of beta-2 ...
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Effect of sympathomimetics on gastrin secretion from antral G cells in culture
... a beta- adrenergic ...of beta-adrenergic receptors on the G ...(a beta 2 agonist) significantly stimulated gastrin release above basal which could be blocked by the addition of ...
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Validation of sensitive spectrophotometric method for determination of Salmeterol xinafoate and Fenoterol hydrobromide via o-Phenanthroline and iron complexation
... A Simple, accurate and sensitive spectrophotometric method has been established and validated for the determination of two selective beta-2 agonist drugs namely; Salmeterol xinafoate and Fenoterol ...
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Reactivation of latent HIV 1 in central memory CD4+T cells through TLR 1/2 stimulation
... in 2 of the 7 patients compared with 5 of 7 for ...of 2 ART-suppressed patients, although, as is gen- erally seen with HDAC inhibitors, the frequency of induc- tion of HIV outgrowth was greater after cells ...
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A qualitative evaluation of the implementation of guidelines and a support tool for asthma management in primary care
... Seven focus group sessions were held with key stake- holders in asthma management in the primary care setting and those targeted in the SABA guideline and AAP card im- plementation. Including a range of stakeholder ...
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Effects of Dietary Beta-Adrenergic Agonist, Terbutaline, on Carcass Characteristics and Blood Attributes in Japanese Quails (Coturnix coturnix japonica)
... 2007). Beta- adrenergic agonists have considerable effects on carcass characteristics (Mersmann, ...of beta agonists in improved feed utilization, increased leanness, increased dressing percentage, ...
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Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts
... Fibroblasts can both respond to, and secrete proin- flammatory cytokines. The well characterized proinflam- matory cytokine, TNFa, in our model system induced secretion of CXCL10, CCL5 and GM-CSF. CXCL10 and CCL5 are ...
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Beta Adrenergic Receptors of Polymorphonuclear Particulates in Bronchial Asthma
... In further studies we examined the interaction of the agonist (−)-isoproterenol with beta adrenergic receptors in 8 normal subjects and 10 asthmatics not receiving adrenergic medication. We tested the ...
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Profile of mirabegron in the treatment of overactive bladder: place in therapy
... the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Over- active Bladder (SCORPIO), Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients ...
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Role of alpha adrenoceptors in opossum internal anal sphincter
... alpha- 2 adrenoceptors exert important neuromodulatory influences on rectoanal inhibitory reflex, while alpha-1 adrenoceptors may exert modulatory effects on the resting IAS ...
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Protective effects of a glucocorticoid on downregulation of pulmonary beta 2 adrenergic receptors in vivo
... increased beta 1- and beta 2-receptor numbers by 70 and 69% above control, respectively, but did not change their mRNA ...days 2-8) decreased beta 1- and beta 2-receptor ...
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The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice
... by 2–3 weeks of age, and hypergly- cemia by 5–6 weeks of age with decreased whole body glucose uptake, failure to suppress hepatic gluconeogen- esis in response to insulin and pancreatic beta cell ...
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C Jun NH2 Terminal Kinase Contributes to Dexmedetomidine Induced Contraction in Isolated Rat Aortic Smooth Muscle
... lysed in PRO-PREP protein extract solution for total cell lysates, and the lysates were centrifuged at 100,000×g for 20 min at 4°C. Protein concentration was determined using the Bradford method. For preparation of ...
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