beta cell mass
A simple matter of life and death : the trials of postnatal beta cell mass regulation
... Do Beta-Cells Maintain Their Normal Mass? Beta-cell mass is increased by neogenesis (differentiation from beta- cell precursor cells), proliferation, and cell ...
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Increasing beta cell mass to treat diabetes mellitus
... of beta cells in order to conserve beta cell ...of beta cells to conserve beta cell function have also been ...of beta cells in rodents; they are, however, unable to ...
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Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice
... the beta cell mass in the graft and lead to failure of the ...of beta cell replication and mass after transplantation of insufficient, minimally sufficient, or excessive islet ...
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Detection of amplifiable mRNA extracellular to insulin producing cells: potential for predicting beta cell mass and function
... Nucleic acids were first detected in plasma almost 60 years ago (3 ), and with the recent advances in sensitive and specific analytical techniques, the detection of nucleic acids now has potential as a tool for early ...
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Signals from the neural crest regulate beta cell mass in the pancreas
... of beta-cells must fluctuate in response to long-term changes in energy balance, and any breakdown in the signals that regulate the size of the beta-cell population will impact energy balance and may ...
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Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass
... b-cell mass expansion for future comparison with the POKO mouse which is unable to expand its ...to cell proliferation and survi- val ...b-cell mass in POKO ...in cell cycle ...
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The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass
... (S)-2-(4-chloro-2-(2-chloro-4-(methylsulfonyl)phenox- y)-6-iodophenoxy) propanoic acid (3.1 mg, 5.8 μmol) was dissolved in ethanol (1 mL), and 10% palladium on car- bon (2.9 mg, 27. μmol) and triethylamine (10 μl, 71. ...
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Key words
... the beta-cell mass in the pathophysiology of the pancreas has been the focus of extensive research ...The mass of beta cells is an important tool for the regulatory mechanisms where ...
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Mathematical Model for the Dynamics of Glucose, Insulin and β Cell Mass under the Effect of Trauma, Excitement and Stress
... of beta cell masses: 300, 600 and 900 were ...condition, beta-cell mass had significant effect in glucose ...of beta cell mass had less effect in glucose ...
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Advancement in Therapeutic Efforts and Tools for Prevention and Treatment of Insulin Dependent Diabetes Mellitis
... of beta cell mass, non -endocrine cell production, antigen-based therapy, pancreatic transplantation, use of immunosuppressive monocyte and control of IDDM by using naturally found CD4 + ...
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The Role of c-Kit Receptor Tyrosine Kinase in Beta-Cell Proliferation, Function and Survival
... in cell culture has further revealed that c-Kit-enriched cells can give rise to new beta-cells that secrete insulin in a glucose-responsive fashion ...decreased cell proliferation and increased ...
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Transplanted beta cell response to increased metabolic demand Changes in beta cell replication and mass
... transplanted beta cells to modify their replication and mass when stimulated by changes in metabolic ...transplanted beta cells increased in Tx-Px ...pancreatic beta cells (0.38 +/- 0.05%) (P ...
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Re expression of IGF II is important for beta cell regeneration in adult mice
... enhance beta cell numbers or even to mitigate against the consequences of beta cell ...during beta cell regeneration in vivo has received limited attention to ...which ...
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Latent autoimmune diabetes of adulthood: case report
... her beta cell mass to decrease, which resulted in having more features of type 1 diabetes than other adult patients with LADA, who do not require insulin at diagnosis [4, ...
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Maintaining Glucose Homeostasis in Response to Aging and Stress: The Role of Pcif1, Bmi1, and Pdx1
... of beta cells to maintain adequate function and mass is central to the development of all forms of ...functional beta cell ...of beta cells and the potential role of Pcif1 in regulating ...
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Glucose and aging control the quiescence period that follows pancreatic beta cell replication
... other cell cycle proteins in the regulation of the refractory ...the cell cycle and for establishing the likelihood of cell cycle ...in beta cells under different physiological stimuli, such ...
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The role of c-Kit and insulin receptor tyrosine kinases in beta cell function and insulin secretion
... in beta cells did not influence glucose tolerance or islet architecture in ND mice, which is in contrast to the loss of first-phase insulin secretion and the reduction in beta cell mass and ...
231
Cell therapies for pancreatic beta-cell replenishment
... Pancreatic ducts, exocrine pancreas and islet of Langerhans are proposed as sources of pancreatic stem/progenitor cells. Although their nature and even their existence were ini- tially subject of controversy in the field ...
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The Luminosity Function of Galaxies as Modeled by a Left Truncated Beta Distribution
... χ < χ . All the previous LFs cover the range [ 0,∞ ] and therefore the analysis of finite upper and lower boundaries can be a subject of investigation. Another interesting observational fact is that at low values of ...
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A New Fuzzy Control Model for Kidney Patients
... pancreatic beta cell or beta cell function, BMI, length of dialysis before transplantation, systolic and diastolic blood pressure be- fore and after the ...
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