binding characteristics
Binding characteristics of the ovine membrane progesterone receptor alpha and expression of the receptor during the estrous cycle
... P4 binding to a membrane PR ...steroid binding charac- teristics of the ovine mPRα is ...the binding kinetics of this puta- tive ...steroid binding characteristics [9]. Saturable ...
9
An Analysis of the Binding Characteristics of a Panel of Recently Selected ICAM-1 Binding Plasmodium falciparum Patient Isolates.
... variable binding to ICAM-1 is thought to be due to differences in the contact residues between this receptor and the variant ...ICAM-1 binding DBLb domains from non-binding ones, which has only been ...
8
Alterations in binding characteristics of the human immunodeficiency virus enhancer factor.
... Because HeLa cell extracts gave altered binding characteristics over the enhancer region in response to different fragments -218 LTR3 compared to -160 LTR3, we used each of these fragmen[r] ...
8
A Correlative Multi-Spectroscopy and Docking Study for the Modeling of Drug (Luteolin and Quercetin) Binding to Bovine Serum Albumin– A Tool for the Determination of Binding Characteristics to Receptor Proteins
... possible binding-induced changes in the interactions with tyrosine and ...of binding (cooperativity and the Hill coefficient) under optimized ...based binding studies were done and LIGPLOT-based ...
13
The binding characteristics of isoniazid with copper–zinc superoxide dismutase and its effect on enzymatic activity
... The binding mechanism, binding constants, binding sites and binding distance were ...the binding force was analyzed based on the thermodynamic ...
8
Binding characteristics of Rauscher leukemia virus envelope glycoprotein gp71 to murine lymphoid cells.
... This is further evidenced by the high binding affinity for R-MuLV gp7l exhibited by lymphoid cells from NZB mice, a strain known to produce high titers of xenotropic virus 20 and whose t[r] ...
7
A single amino acid in the HA of pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets
... receptor binding characteristics might be affected by mutation at residue 227, we compared the cell tropism in cultures of primary HAE of a pH1N1 2009 strain A/England/195/09 (E195) to the HA mutant E195 ...
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Induction of susceptibility to tumor necrosis factor by E1A is dependent on binding to either p300 or p105-Rb and induction of DNA synthesis.
... by binding to cellular proteins ...protein binding characteristics were employed to determine the relationship between E1A binding to these pro- teins and E1A induction of susceptibility to ...
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Sex steroid binding proteins in fish
... The effects of short term confinement stress on binding characteristics of sex steroid binding protein SBP in female black bream Acanthopagrus butcheri and rainbow trout Oncorhynchus myk[r] ...
196
Characterization of beta adrenoreceptors of rainbow trout (Oncorhynchus mykiss) erythrocytes
... Based on the binding characteristics after intentional lysis of erythrocytes, it is shown that the total receptor population of trout erythrocytes can be estimated by propranololdisplace[r] ...
18
Myometrial angiotensin II receptor subtypes change during ovine pregnancy
... (AT) binding in vascular and uterine smooth muscle is similar in nonpregnant animals, studies suggest it may differ during ...examined binding characteristics of myometrial AT receptors in ...
10
Searching the protein structure database for ligand binding site similarities using CPASS v 2
... structural characteristics of experimentally determined ligand binding sites to infer a functional relationship in the absence of global sequence or structure ...ligand-defined binding sites has ...
15
Lignocellulose binding of a Cel5A-RtCBM11 chimera with enhanced β-glucanase activity monitored by electron paramagnetic resonance
... arcane by direct measurement with EPR spectroscopy. In contrast to many previous reports, our results have demonstrated that only low levels of protein bind to sam- ples in which lignin is present. Our results further ...
11
Molecular Mechanisms of Serum Resistance of Human Influenza H3N2 Virus and Their Involvement in Virus Adaptation in a New Host
... Virus receptor-binding affinity. The virus-binding affinity for serum sialylgly- coproteins inhibitors, sialosides, and sialylglycopolymers was assessed by using the solid-phase fetuin-binding ...
8
Beta receptor occupancy Assessment in the intact animal
... 125I-hydroxybenzylpindolol binding as did the antagonist, ...receptor binding accounted for 50% of total uptake in the lung and demonstrated the following ...125I-hydroxybenzylpindolol binding ...
9
Familial Hypercholesterolemia: EVIDENCE FOR A NEWLY RECOGNIZED MUTATION DETERMINING INCREASED FIBROBLAST RECEPTOR AFFINITY BUT DECREASED CAPACITY FOR LOW DENSITY LIPOPROTEIN IN TWO SIBLINGS
... The residual LDL receptor activity was clearly qualitatively abnormal. The Michaelis constant (K m ) for 125 I-LDL was reduced to 20-40% of normal, indicating a substantially increased affinity for LDL. Increased ...
10
Characterization, localization and solubilization of P2x-purinoceptors
... binding sites are or are linked to P2x"Pui'ii^oceptors (Burnstook & Kennedy, 1985). In a pharmacological experiment on human bladder, it was observed that o,&-MeATP, A6PA, &,Y-MeATP, ADP&S and ...
355
Synthesis and evaluation in rats of homologous series of [18F]-labeled dopamine D2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers
... sentatives of only two classes, namely the apomorphines [ 11 C](−)NPA and [ 11 C]MNPA and the naphtoxazine [ 11 C](+)PHNO, have hitherto been used in human PET studies. These tracers can only be used in hospitals with an ...
13
Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
... Genetic mutations and copy number changes can dramatically influence gene expression, but they emerge in cancer cells over many years of biologic selection [8]. Molecular pathway changes at the RNA level represent a ...
20
Genome-wide binding of the basic helix-loop-helix myogenic inhibitor musculin has substantial overlap with MyoD: implications for buffering activity
... Recently, we have shown that MSC competes with MyoD for the available pool of E-proteins in rhabdo- myosarcoma cells [18], and that it occludes MyoD bind- ing sites, interfering with myogenic activation [19]. ...
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