Bioactive Sequences in Self-Assembling Peptide (SAP) Hydrogels
Novel Growth Factor Delivery Systems from Self-Assembling Peptide (SAP) Hydrogels
... specific sequences within these proteins are known to influence intracellular processes including adhesion, proliferation, differentiation, and ...these peptide sequences into multicomponent ...
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Amino acid composition of nanofibrillar self-assembling peptide hydrogels affects responses of periodontal tissue cells in vitro
... diverging peptide sequences of P11-4 and P11-8, resulting in either a negative or a positive surface ...the peptide sequence of P11-8 contains ornithine residues that lead to an overall positive ...
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A cell-free SDKP-conjugated self-assembling peptide hydrogel sufficient for improvement of myocardial infarction
... Regenerative therapy for ischemic heart diseases, including cell-based therapy and cell-free approaches such as biomaterial scaffolds and delivery of bioactive molecules, is an active field of research that has ...
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Bioinspired Self-assembling Peptide Hydrogel with Proteoglycan-assisted Growth Factor Delivery for Therapeutic Angiogenesis
... livers, peptide solution was directly injected into the bleeding site and immediately formed hydrogel in ...SAP hydrogels in oozing wounds or even in minimally invasive surgical ...The ...
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Responsive hydrogels using self-assembling polymer-peptide conjugates
... the peptide fibres and/or with the polymer segments present along peptide fibres thus contributing to the fibre stiffening, creating additional entanglements or physical cross-links and increasing gel ...of ...
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Self-assembling peptide hydrogels : directing cell behaviour by chemical composition
... 1 Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA Biomedical engineers can easily find inspiration for exciting re- search directions by looking to the oceans. Barnacles, starfish, sea ...
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Functionalized D-form self-assembling peptide hydrogels for bone regeneration
... RADA16-I peptide scaffolds are capable of controlled release of various functional proteins, including basic fibroblast growth factor (bFGF), vascular endothe- lial growth factor, brain-derived neurotrophic ...
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Self-assembling peptide hydrogels : directing cell behaviour by chemical composition
... 1 Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA Biomedical engineers can easily find inspiration for exciting re- search directions by looking to the oceans. Barnacles, starfish, sea ...
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Self-assembly of bioactive peptides, peptide conjugates, and peptide-mimetic materials
... the peptide with receptor directly or via shifts in the molecule-aggregate ...(YGRKKRRQRRR) peptide from HIV retrovirus which has been shown to have antimicrobial properties, and contains 6 arginine and 2 ...
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Self-assembling peptide hydrogel for intervertebral disc tissue engineering
... scaffolds. Self-assembling peptide hydrogels (SAPHs) combine advantages of both natural and synthetic biomaterials; for example they are biocompatible and have easily modifiable ...
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Electrostatic effects on nanofiber formation of self-assembling peptide amphiphiles
... of self-assem- bling PAs is important for design and synthesis of the ...their self-assembly mechanisms by various characterization methods. PAs self-assemble into nanof- ibers, which provide useful ...
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Self-assembling microsphere-based dextran hydrogels for pharmaceutical applications. Sophie Van Tomme
... of hydrogels with specific cell-binding peptide sequences, strongly enhances the cell viability and proliferation and can promote ...The self-assembling microsphere- based dextran ...
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A self-assembling peptide RADA16-I integrated with spider fibroin uncrystalline motifs
... R4 hydrogels is greater than that of RADA16-I ...prevent peptide R4 from forming unordered structure, and the hydrophobic phenyl ring of tyrosine may promote affinitive aggregation of ...the ...
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Sustained and controlled release of lipophilic drugs from a self-assembling amphiphilic peptide hydrogel
... peptides as a carrier for controlled drug release of lipophilic drugs. By using AFM we have demonstrated that the addition of functional drugs motif 407. sequences has no distinct i[r] ...
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CHARMM force field parameterization protocol for self-assembling peptide amphiphiles : the Fmoc moiety
... to self-assemble into nanostructures with very interesting applications in nanotechnology and ...of peptide- based nanomaterials is due not only to the functional groups present in the molecules but also ...
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Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo
... of self-assembling peptides has been extensively explored to identify hydrophobic anticancer agents and small interfering ...21–23 Self-assembling peptide-based delivery systems have ...
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Self-Assembling Peptide Hydrogel for Local Anticancer Prodrug Delivery in the Treatment of Glioblastoma Multiforme
... in Peptide Hydrogels The amount of TMZ loaded into each rehydrated peptide hydrogel was determined using an HPLC system consisting of a Waters Model 2707 Autosampler connected to a 1515 Isocratic ...
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Exploring the sequence space for (tri-)peptide self-assembly to design and discover new hydrogels
... larger peptide box (1,200 ns, 1,200 peptides, ...for self-‐assembling nanostructures after 50 ns, structural information can be obtained as well with much longer, extended, simulations as was ...
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Controlled release of TGF-beta 1 from RADA self-assembling peptide hydrogel scaffolds
... that self-assembling peptide nanofiber hydrogel scaffolds have been found to exert a significantly favorable influence on bone and cartilage regen- eration, wound healing, as well as drug ...ionic ...
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Self-Assembling Peptide Nanomaterials: Molecular Dynamics Studies, Computational Designs And Crystal Structure Characterizations
... Self-Assembling Peptide Nanomaterials: Molecular Dynamics Studies, Computational Designs And Crystal Structure Characterizations Abstract Peptides present complicated three-dimensional folds encoded ...
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