BMP signalling
BMP signalling in craniofacial development
... epithelial signalling mediated by Bmp4 and Bmp7 is either unessential or functional redundant with others as impli- cated by conditioned knockout models (Dudley et ...the Bmp family do not appear crucial ...
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BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2
... ing BMP function during primordial follicle formation in the mouse ovary (Myers et ...of BMP signalling ...of BMP action on the somatic compartment of the developing ...the BMP system ...
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A change in response to Bmp signalling precedes ectodermal fate choice
... by Bmp signalling once endogenous smad1 expression appears, we next asked if ectopic expression of smad1 prior to gastrulation would lead to repression of sox2 and sox3 expression at the 50% epiboly ...
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X epilectin: a novel epidermal fucolectin regulated by BMP signalling
... antagonizing BMP signalling, can induce cement gland tissue at low doses and neural tissue at higher doses (Knecht and Harland, ...for BMP signalling in Xenopus ...the BMP pathway, we ...
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Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome
... Hh signalling, and activated Smads (pSmads), mediators of bone morphogenic protein (BMP) signalling, in ...Hh signalling is ...upon BMP signalling ...the BMP and Hh ...
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BMP signalling inhibits premature neural differentiation in the mouse embryo
... cells, BMP signalling has been implicated in the maintenance of pluripotency (Qi et ...that BMP signalling is required to maintain epiblast ...
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Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion
... blocking BMP signalling by expression of dominant-negative BMPR2 enhances prostate cancer ...mutant BMP receptors have been identified in primary human EOC cells, however an intact autocrine BMP4 ...
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The integrated stress response regulates BMP signalling through effects on translation
... crc, the Drosophila homologue of ATF4, also inhibits MAD phosphorylation. The large number of genes sen- sitive to crc suggests that its effect on BMP signalling may be multifaceted. Our data reveal, ...
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Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling
... and BMP signalling pathways have been shown to play crucial roles in formation and patterning of mesoderm and endoderm in ...Nodal signalling to induce the co-receptor Oep in cells distant from the ...
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Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains
... If Bmp signalling can still occur in vegetal ectoderm without suppressing sox3 expression, then this raises the issue of what Bmp activity is doing in this ...ectoderm, Bmp activity promotes ...
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Temporal control of BMP signalling determines neuronal subtype identity in the dorsal neural tube
... for BMP signalling at distinct developmental time ...the BMP pathway would allow higher levels of signalling to be attained and therefore more dorsal populations to be ...inhibit BMP ...
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Transient downregulation of Bmp signalling induces extra limbs in vertebrates
... Bmp signalling has been implicated in DV patterning and distal outgrowth of the vertebrate limb (Ahn et ...2001). Bmp is involved in positioning the AER by inducing en1 in the ventral limb ectoderm ...
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The Interplay between Hedgehog Signalling and BMP Signalling in Regulating B cell Development
... a BMP inhibitor, Noggin, suggesting that both Hh and BMP signalling are required to take place for these early events in B cell activation and that the synergy requires BMP signalling ...
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BMP signalling controls the construction of vertebrate mucociliary epithelia
... that BMP signalling is required to activate dll1 expression in the Xenopus developing epidermis, although the absence of clear Smad consensus binding sites upstream of the dll1 open reading frame (data not ...
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Regulation of the BMP signalling pathway by BMP1-related metalloproteases
... P signalling is required for dorsal ...P4 signalling. In fact, inhibition o f ventral signalling may be a general role of the organizer, since XwntS signalling from the ventral side of the X ...
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Distinct roles of BMP and LKB1/AMPK signalling impacting ovarian cancer spheroid biology
... Uncovering potential novel mechanisms of disease hidden within a gene expression signature is more readily attainable when compared to the large number of published datasets available. One such useful resource is ...
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Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition
... both BMP-dependent and -independent ...a BMP-dependent action of FGF, Bmp4 expression is upregulated in the dorsal ectoderm of FGFR- deficient embryos, which appears to be a conserved feature in vertebrates ...
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A balance of FGF, BMP and WNT signalling positions the future placode territory in the head
... different signalling molecules including FGFs (Shamim and Mason, 1999; Ohuchi et ...the BMP antagonist DAN (Ogita et al., 2001), and the BMP and WNT antagonist Cerberus (Rodriguez Esteban et ...of ...
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RPE specification in the chick is mediated by surface ectoderm derived BMP and Wnt signalling
... different signalling pathways integrate to regulate cell fate decisions within the ...the BMP-expressing surface ectoderm rather than the mesenchyme is involved in RPE specification (reviewed by Clegg et ...
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Bone morphogenetic proteins enhance an epithelial-mesenchymal transition in normal airway epithelial cells during restitution of a disrupted epithelium
... of BMP signalling, negatively regulates BMP4 during lung branching morphogenesis ...of BMP signalling in adult lungs in health, regeneration or ...(BMP) signalling is an early ...
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