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Bone erosion

Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis

Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis

... in bone erosion and the underlying mechanism of AD-mediated bone erosion in ...gressive bone erosion in patients with RA [10] and that AD aggravates the process by enhancing the ...

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Bone marrow mesenchymal stem cells improve bone erosion in collagen-induced arthritis by inhibiting osteoclasia-related factors and differentiating into chondrocytes

Bone marrow mesenchymal stem cells improve bone erosion in collagen-induced arthritis by inhibiting osteoclasia-related factors and differentiating into chondrocytes

... damage, bone marrow suppression, and psycho- logical ...joint erosion upon imaging examination [1, ...joint erosion cannot be effectively repaired through pharmacotherapeutic intervention, thereby ...

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Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner

Norisoboldine, an Anti-Arthritis Alkaloid Isolated from Radix Linderae, Attenuates Osteoclast Differentiation and Inflammatory Bone Erosion in an Aryl Hydrocarbon Receptor-Dependent Manner

... Fig. 5. Effects of α-naphthoflavone (α-NF) on the anti-bone destruction effect of norisoboldine (NOR) in collagen-induced arthritis (CIA) rats. The rats were intradermally injected with CII emulsion on day 0 and ...

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TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis

... in bone mar- row plasma cells in patients with multiple myeloma ...serum bone resorption marker, b -crosslaps, and levels of the osteoclast recruitment chemokine, CXCL12, strongly implying a pathological ...

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Delivery of miR-146a to Ly6Chigh Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

Delivery of miR-146a to Ly6Chigh Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

... or bone destruction, the two main features of the disease ...on bone erosion by demonstrating that enforced express- ion of miR-146a in Ly6C high , and not in Ly6C low , ...

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Suppression of arthritis induced bone erosion by a CRAC channel antagonist

Suppression of arthritis induced bone erosion by a CRAC channel antagonist

... weeks. Bone and cartilage damage in sections of animal feet was reduced approximately 50%; overall swelling of joints was reduced by a similar ...on bone density by µCT showed clear separation in ...

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Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion

Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion

... and bone erosion in in vivo models of RA, even in the presence of persistent joint inflammation ...new bone formation ...of bone pathology in PsA, in the form of either new bone ...

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Comparison of Digital X-Ray and USG Detected bone Erosion in Newly Diagnosed Rheumatoid arthritis Patients (less than 2 years) Attending a Tertiary Care Hospital in Kolkata

Comparison of Digital X-Ray and USG Detected bone Erosion in Newly Diagnosed Rheumatoid arthritis Patients (less than 2 years) Attending a Tertiary Care Hospital in Kolkata

... Salaffi, et al and Naredo, et al suggested in their studies that bone erosion correlated better with persistently high disease activity. Joshua F Baker, et al had similar outcome from his study. he ...

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IL 4 gene therapy for collagen arthritis suppresses synovial IL 17 and osteoprotegerin ligand and prevents bone erosion

IL 4 gene therapy for collagen arthritis suppresses synovial IL 17 and osteoprotegerin ligand and prevents bone erosion

... and bone erosion in the knees of mice with collagen arthritis ...joint erosion and more compact bone structure in the Ad5E1mIL-4 ...prevented bone erosion and diminished ...

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Fcγ receptor mediated influx of S100A8/A9 producing neutrophils as inducer of bone erosion during antigen induced arthritis

Fcγ receptor mediated influx of S100A8/A9 producing neutrophils as inducer of bone erosion during antigen induced arthritis

... suggests that particularly FcγRIV is responsible for the presence of neutrophils to the joint. The importance of neutrophils in RA development has been shown in the K/ B×N experimental RA model [31]. Moreover, in ...

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Large dentigerous cyst in the maxillary sinus causing bone erosion of the sinus walls

Large dentigerous cyst in the maxillary sinus causing bone erosion of the sinus walls

... Dentigerous cyst is an asymptomatic developmental abnormality usually discovered on routine radiological investigation for various dental conditions. It is suspected when there is late non-eruption of tooth. DC should be ...

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Case Report Clinical and pathological features in a case of angiomatous nasal polyp

Case Report Clinical and pathological features in a case of angiomatous nasal polyp

... Abstract: Angiomatous nasal polyp (ANP) is a relatively rare benign lesion, which may be misdiagnosed as a benign or malignant tumor. The characteristic pathological features of ANP are extensive vascular proliferation, ...

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Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis   effects of age and disease duration

Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis effects of age and disease duration

... erosive bone damage in an individual with PsA has to consider age as an important influencing ...of bone erosions is also supported by the notion that the duration of PsA is associated with the burden of ...

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Relationship of Patient-Reported Outcomes with MRI Measures in Rheumatoid Arthritis

Relationship of Patient-Reported Outcomes with MRI Measures in Rheumatoid Arthritis

... This study was a secondary analysis of the GO-BEFORE (Clintrials.gov identifier NCT00361335) randomized trial MRI sub-study. Details of the trial design and results have been previously published.[12-14] The GO-BEFORE ...

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promotes cell migration and has been implicated in arterial tissue-repair processes. Furthermore, high CTHRC1 expression is observed in many types of cancer and this is

promotes cell migration and has been implicated in arterial tissue-repair processes. Furthermore, high CTHRC1 expression is observed in many types of cancer and this is

... and bone resulting in major damage of the intimal lining and sub lining layers of the synovial tissue and, eventually, resulting in joint ...of bone erosion; these cells become proliferative, ...

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Canada Denmark MRI scoring system of the spine in patients with axial spondyloarthritis: updated definitions, scoring rules and inter reader reliability in a multiple reader setting

Canada Denmark MRI scoring system of the spine in patients with axial spondyloarthritis: updated definitions, scoring rules and inter reader reliability in a multiple reader setting

... spine bone erosion score’ and ‘CANDEN MRI spine new bone formation score’ should be used only when all components are scored and calculated as described in this ...

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Anatomical location of erosions at the metatarsophalangeal joints in patients with rheumatoid arthritis

Anatomical location of erosions at the metatarsophalangeal joints in patients with rheumatoid arthritis

... higher erosion scores at the MTP joints are associated with higher peak pressure values in the forefoot of patients with ...highest erosion score in the fore- foot were seen at the fifth MTP ...with ...

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Fibrous Arthropathy Associated With Morphea: A New Cause of Diffuse Acquired Joint Contractures

Fibrous Arthropathy Associated With Morphea: A New Cause of Diffuse Acquired Joint Contractures

... Etiologies for childhood-onset diffuse joint contractures encompass a large group of inherited disorders and acquired diseases, in particular a subtype of juvenile idiopathic arthritis called “dry polyarthritis, ” ...

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Morphologic patterns and imaging features of intracranial hemangiopericytomas: a retrospective analysis

Morphologic patterns and imaging features of intracranial hemangiopericytomas: a retrospective analysis

... cranial bone was found in three patients, including two patients with temporal bone erosion (Figure 6A), and one with erosion of the anterior cranial ...

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Early anti inflammatory intervention ameliorates axial disease in the proteoglycan induced spondylitis mouse model of ankylosing spondylitis

Early anti inflammatory intervention ameliorates axial disease in the proteoglycan induced spondylitis mouse model of ankylosing spondylitis

... destruction. Bone erosion score: 0, no erosion; 1, one or a few small areas of re- sorption in original vertebral bone; 2, numerous areas of obvious focal resorption in original vertebral ...

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