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Bone marrow cell survival

Ghrelin as a Novel Therapy for Radiation Combined Injury

Ghrelin as a Novel Therapy for Radiation Combined Injury

... improved survival rates from 0% to 60% in 30 ...the survival rate, peripheral white blood cell counts and bone-marrow nucleated cells, suggesting NGF could be therapeutic for wound ...

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Role of geometrical cues in bone marrow derived mesenchymal stem cell survival, growth and osteogenic differentiation

Role of geometrical cues in bone marrow derived mesenchymal stem cell survival, growth and osteogenic differentiation

... extrapolating cell numbers in 3D samples using 2D standard curves may provide an inaccurate measure of cell proliferation in 3D, as done by some studies using titanium phosphate-based glass microspheres for ...

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Ghrelin therapy mitigates bone marrow injury and splenocytopenia by sustaining circulating G-CSF and KC increases after irradiation combined with wound

Ghrelin therapy mitigates bone marrow injury and splenocytopenia by sustaining circulating G-CSF and KC increases after irradiation combined with wound

... improve survival after ...hematopoietic cell death and its related sign- aling molecules such as granulocyte-colony stimulating factor (G-CSF) and keratinocyte chemattractant (KC) at early time ...and ...

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Diabetic Bone Marrow & Stem Cell Dysfunction

Diabetic Bone Marrow & Stem Cell Dysfunction

... the survival or maintenance of these cells in an SC-like ...modified survival assay, I profiled how the expression of SC markers changed over time in co-cultures of CD133+ cells with MPCs or MPC- derived ...

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Role of Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into β Cells in the Pancreatic Microenvironment

Role of Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into β Cells in the Pancreatic Microenvironment

... Studies have shown that the induced differentiation of stem cells is controlled by their intrinsic genetic program and surrounding microenvironment, which determines the fate of adult stem cells differentiation. ...

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Bone Marrow Morphology in Multiple Myeloma.

Bone Marrow Morphology in Multiple Myeloma.

... that provide the soil for their homing and maturation to mature plasma cells, which secrete a range of cytokines. Subsequent development and dissemination of MM is controlled by BM microenvironment which in turn is ...

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Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival

Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival

... in bone marrow and peripheral blood, as this was the available and most standardized method at the time of the study ...proliferating cell clone in the ...

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Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats

Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats

... brief, bone marrow tissues were acquired by flushing the cavities of femurs and tibias with basal Dulbecco’s modified Eagle’s ...Collected bone marrow cells were seeded into flasks with ...

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The presence and prognostic impact of apoptotic and nonapoptotic disseminated tumor cells in the bone marrow of primary breast cancer patients after neoadjuvant chemotherapy

The presence and prognostic impact of apoptotic and nonapoptotic disseminated tumor cells in the bone marrow of primary breast cancer patients after neoadjuvant chemotherapy

... Conversely, DTCs that are the result of an active pre- metastatic process might undergo apoptosis, caused by systemic efficacy of NACT. However, chemotherapy is often unable to eradicate nonproliferating DTCs [27]. In- ...

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Bone marrow mononuclear cells and acute myocardial infarction

Bone marrow mononuclear cells and acute myocardial infarction

... stem cell delivery that have been used so far in clinical trials are through intracoronary or intramyocardial injection or peripherally through the systemic ...

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In vivo experience with natural scaffolds for myocardial infarction: the times they are a-changin’

In vivo experience with natural scaffolds for myocardial infarction: the times they are a-changin’

... regulated cell differentiation [124], experiments were conducted to assess the effectiveness of bone marrow mononuclear cells (BMMNCs) [124, 125] and bone marrow MSCs [126] for treating ...

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A microenvironment mediated c Myc/miR 548m/HDAC6 amplification loop in non Hodgkin B cell lymphomas

A microenvironment mediated c Myc/miR 548m/HDAC6 amplification loop in non Hodgkin B cell lymphomas

... that cell adhesion to stroma cells (HK and HS-5 cells) confers a multidrug-resistant pheno- type and that disruption of cell adhesion–mediated signaling may increase the efficacy of cytotoxic agents (2, ...

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Clinico-hematological study in pancytopenia patients presenting to tertiary care hospital

Clinico-hematological study in pancytopenia patients presenting to tertiary care hospital

... The same skin incision to use to perform core biopsy, and adjust the needle for inserting at a different angle into bone. Needle introduce in a clockwise rotation with a stylet, after entering into periosteum ...

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Effect of L lysine in culture medium on nodule formation by bone marrow cells

Effect of L lysine in culture medium on nodule formation by bone marrow cells

... sonicated cell suspension was used for measurement of ALP activity ...tured bone marrow stem cells with and without addition of Lys in the culture medium was represented as μM p-nitrophenol released ...

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Clinical performance of stem cell therapy in patients with acute on chronic liver failure: a systematic review and meta analysis

Clinical performance of stem cell therapy in patients with acute on chronic liver failure: a systematic review and meta analysis

... BMCs: bone marrow cells; PRISMA: preferred reporting items for systematic reviews and meta-analyses; SMTs: standards medical treatments; MD: mean difference; CI: confidential interval; CLD: chronic liver ...

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Mesenchymal stem cell transplantation as an effective treatment strategy for ischemic stroke in Asia: a meta-analysis of controlled trials

Mesenchymal stem cell transplantation as an effective treatment strategy for ischemic stroke in Asia: a meta-analysis of controlled trials

... To further evaluate the effects of clinical variables including cell types and different administration routes on clinical effi- cacy of patients with different characteristics, we performed subgroup analysis. ...

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Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

... late bone formation [11] and are at the same time potent inhibitors of MM cell survival ...and survival of tumour cells ...squamous cell carcinomas ...leukemia cell proliferation ...

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Comparison of Platelet-Rich Plasma (PRP), Bone Marrow-Derived Mesenchymal Stem Cells‏ and their Combination on the Healing of Achilles Tendon in Rabbits

Comparison of Platelet-Rich Plasma (PRP), Bone Marrow-Derived Mesenchymal Stem Cells‏ and their Combination on the Healing of Achilles Tendon in Rabbits

... (a) tissue inflammation, (b) cell and matrix proliferation, and (c) remodeling and maturation. The inflammatory stage usually includes a hematoma formation, thereby triggering the discharge of chemotactic factors ...

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Activation of Notch1 signalling promotes multi-lineage differentiation of c-KitPOS/NKX2.5POS bone marrow stem cells: implication in stem cell translational medicine

Activation of Notch1 signalling promotes multi-lineage differentiation of c-KitPOS/NKX2.5POS bone marrow stem cells: implication in stem cell translational medicine

... stem cell research ...desired cell numbers for in vivo transplantation is time consuming because heart tissue-derived CSCs grow ...accessible cell source that can be substituted for endogenous ...

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Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke

Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke

... BMSCs originate from bone marrow mononuclear cells (BMMNCs). The floating cells are removed from BMMNCs, and only cells adhering to the floor of the flask are cultured for several weeks to obtain BMSCs [4]. ...

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