Bone Marrow Failure
Original Article Evaluation of related abnormal metabolite profiles in patients with bone marrow failure syndrome (BMFS)
... Acquired bone marrow failure syndromes (BM- FSs) are characterized by hematopoietic stem and (or) progenitor cell damage in the bone marrow, as well as a subsequent decrease in a single ...
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Clinical and Genetic Analysis of Unclassifiable Inherited Bone Marrow Failure Syndromes
... Inherited Marrow Failure Registry were registered as having unclassified inherited bone marrow failure ...inherited bone marrow failure syndrome (median: 1 month) ...
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18F-FLT PET/MRI for bone marrow failure syndrome-initial experience
... Bone marrow failure syndrome (BMFS) is a heterogeneous group of disorders associated with single- or multiple-lineage cytopenia and failure of normal hematopoiesis that can be either inherited ...
9
Bone marrow failure may be caused by chromosome anomalies exerting effects on RUNX1T1 gene
... BM: Bone marrow; BMFS: Bone marrow failure syndromes; CAMT: Congenital amegakaryocytic thrombocytopenia; DBA: Diamond-blackfan anaemia; DEB: Diepoxybutane; EBV: Epstein-Barr virus; FA: ...
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Pregnancy in fanconi anaemia with bone marrow failure: a case report and review of the literature
... Fanconi anaemia (FA) is a heterogeneous genetic syn- drome characterized by congenital abnormalities, bone marrow failure (BMF), with an increased cancer occur- rence [1]. Hematopoietic stem cell ...
5
Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure
... progressive bone marrow failure requiring increasing rates of blood product substitution, and since she showed signs of developing myelodysplastic syndrome (MDS), HSCT was the most promising ...
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Erythropoiesis in the anemia of bone marrow failure
... from bone marrow failure and with polycythemia ...from bone marrow failure, basal levels were elevated, and phlebotomy resulted in an increase consistent with the new level of ...
8
CD106 is a novel mediator of bone marrow mesenchymal stem cells via NF-κB in the bone marrow failure of acquired aplastic anemia
... BM: Bone marrow; BSA: Bovine serum albumin; CCL: Chemokine ligand; CFU: Colony-forming unit; CFU-GEMM: Colony-forming unit mixed cell; CFU-GM: Colony-forming unit-granulocyte macrophage; CV: Chorionic ...
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Dyskeratosis Congenita A Case Report And Review of Literature
... Dyskeratosis congenita, a rare inherited condition, is estimated to occur in 1 in 1 million people. The disease is characterised by a classic triad: nail dystrophy, reticulate skin pigmentation, and oral leukoplakia. ...
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Cytokinesis failure occurs in Fanconi anemia pathway–deficient murine and human bone marrow hematopoietic cells
... cytokinesis failure may contribute to the depletion of HSCs in ...cytokinesis failure and binucleated ...the bone marrow failure observed in ...develop bone marrow disease ...
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Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia A paradigm of human B19 parvovirus infection
... In striking parallel to Bl 9 parvovirus-mediated bone marrow failure in human beings, severe anemia in the cynomolgus monkeys consistently was associated with the presence of a known imm[r] ...
7
A prospective, cross sectional open label clinicoepidemiological study of vitamin B-12 deficiency in adolescent children
... of bone marrow failure, Haemolytic anemia associated with jaundice and organomegaly, Aplastic anemia and leukaemia, and Anemia associated with chronic inflammatory ...
6
Review Article Telomere Dysfunction in Human Diseases: The Long and Short of It!
... knock-out mice are viable and fertile, but exhibit an increase in C-strand degradation. Despite the independent functions of POT1a and POT1b in repressing a DNA damage signal and in regulating the structure of the ...
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Short stature: an ordinary sign for an unordinary diagnosis
... pancreas, bone, cartilage and bone mar- row cells development, but its function is still ...to bone marrow failure, with neutropenia, anemia, thrombocytopenia or pancytopenia; to ...
5
AN EFFECTIVE TECHNIQUE FOR BRAIN TUMOUR SEGMENTATION AND DETECTION USING CUCKOO BASED NEURO FUZZY CLASSIFIER
... fields. Bone Marrow is the flexible tissue found in the interior of ...The bone marrow is used to diagnose diseases such as leukemia, anemia, neimen pick disease and so ...
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CD45lowCD271high Cell Prevalence in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative Therapy
... of Bone and Joint Surgery, ...in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative ...of Bone and Joint ...
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Ethanolic extract of Schizonepeta tenuifolia attenuates osteoclast formation and activation in vitro and protects against lipopolysaccharide induced bone loss in vivo
... BMCs, Bone marrow cells; BMMs, Bone marrow macrophages; BV/TV, Bone volume per tissue volume; DC-STAMP, Dendritic cell-specific transmembrane protein; EEST, Ethanolic extract of ...
9
Intrapulmonary Recombinant Factor VIIa for Diffuse Alveolar Hemorrhage in Children
... pneumonia and died of respiratory failure with diffuse lung fibrosis after 54 days of DAH (day 85 of umbilical cord blood transplantation). UPN2 developed carbapenem-resistant Pseudomonas aeruginosa sepsis, and ...
7
Mast cell–derived angiopoietin 1 plays a critical role in the growth of plasma cell tumors
... ng/ml). Bone marrow mast cells, obtained from C57BL/6 mice (National Cancer Institute), were cultured with 10 ng/ml IL-3 (these are referred to here as BMMCs) or with 100 ng/ml SCF plus 50 ng/ml IL-6 plus ...
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Autologous bone marrow cell therapy for peripheral arterial disease
... BMCs, bone marrow cells; BMSCs, bone marrow stem cells; BM-MNCs, bone marrow–derived mononuclear cells; CLI, critical limb ischemia; DF, diabetic foot; DM, diabetes mellitus; ...
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