boron capture neutron therapy
Boron delivery agents for neutron capture therapy of cancer
... Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the nuclear capture and fission reactions that occur when the stable isotope, boron-10, is ...
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In Vitro Evaluation System of Pharmacokinetics and Irradiation Effect in Boron Neutron Capture Therapy (BNCT) Using Three Dimensional Artificial Human Tumor Tissue Model
... DOI: 10.4236/jct.2019.1010071 838 Journal of Cancer Therapy of 40 ppm with DMEM containing 10% FBS. This is referred to as a BPA treat- ment solution. After removing the culture solution of NHDF3D or NHDF3D/ ...
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Low Temperature and Pressure Synthesis of Lithium Nitride Compound with H2O Addition on Lithium Target for BNCT
... To prevent vaporization damage of BNCT Boron Neutron Capture Therapy lithium target during operation, synthesis of lithiumnitride compound was conducted on the lithium target by N2/H2O [r] ...
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3 (4 Dihydroxyborylphenyl)cyclobutanone1
... chemical therapy or radiation therapy; boron neutron capture therapy (BNCT) has been recently considered as an alternative useful method for treating hepatoma (Aris et ...
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Thermal neutron Relative Biological Effectiveness factors for Boron Neutron Capture Therapy from in vitro irradiations
... the neutron effect would mean that the RBE of the fast neutron dose could depend on the particular facility being used, and might be very different at reactor or accelerator-based ...
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Shielding analyses of an AB-BNCT facility using Monte Carlo simulations and simplified methods
... accelerator-based boron neutron capture therapy (AB-BNCT) facility that included an accelerator room and a patient treatment ...epithermal neutron beam for BNCT purpose was generated by ...
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Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
... of boron to cells which is of interest for BNCT ...thermal neutron irradiation on the antiproliferative activity of both complex 1 and RuMs particles in the A2780 ovarian cancer cell line, and in A2780cisR ...
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Metal complexes as potential anticancer agents
... Boron neutron capture therapy (BNCT) is a type of cancer treatment that combines elements of both radiotherapy and chemotherapy for the destruction of tum ...this therapy is to ...
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Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer
... controlled trial evaluating clinical outcomes of standard systemic therapy in this same category of patients was included to assess standard therapy (Vermorken and Specenier, 2010). The primary outcomes ...
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Deterministic Parsing Model of the Compound Biological Effectiveness (CBE) Factor for Intracellular 10Boron Distribution in Boron Neutron Capture Therapy
... accelerator-based neutron source for neutron capture therapy with lithium target were designed [1]-[3] and many inventions for the progressive power run-up were reported [4] ...
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STUDY OF THE DISCREPANCY BETWEEN ANALYTICAL CALCULATIONS AND THE OBSERVED BIOLOGICAL EFFECTIVENESS IN PROTON BORON CAPTURE THERAPY (PBCT)
... proton therapy facility of INFN-LNS, Catania, ...of Boron nuclei results in an increase of the radiobiological effectiveness of the proton ...a neutron-free nuclear fusion reaction, the relevance of ...
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Plant-Based Calcium Fructoborate as Boron-Carrying Nanoparticles for Neutron Cancer Therapy
... Boron neutron capture therapy (BNCT) is an effective clinical method in cancer treatment based on fission reactions and nuclear ...best boron-containing agents for boron ...
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FBPA PET in boron neutron capture therapy for cancer: prediction of 10B concentration in the tumor and normal tissue in a rat xenograft model
... In this study, we demonstrated the existence of clear correlations between the accumulation levels of BPA-fr and FBPA in the transplanted glioma cells and nor- mal organs in rat xenograft models. This preclinical study ...
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Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy
... glioma therapy mannitol also has the ability to disrupt the blood brain barrier potentially raising the intratumoural concentration of BPA a feature which is known to improve therapeutic outcome 16 ...
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Direct Synthesis of Li3N Thin Layer on Lithium Target Surface for BNCT in N2 Gaseous Conditions
... Implemented deployment of accelerator-driven neutron source for boron neutron capture therapy (BNCT) is scheduled in 2014 in National Cancer Center, Japan. This BNCT system was designed ...
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Clinical trials for treating recurrent head and neck cancer with boron neutron capture therapy using the Tsing-Hua Open Pool Reactor
... and boron neutron capture therapy (BNCT) may be a solution that could provide durable local control with tolerable ...epithermal neutron source for basic and clinical BNCT ...of ...
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Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses
... A 73-year-old woman presented with a black macule on her vulva (Fig. 2a). A small nodular lesion (1.5 cm) was resected for histopathological examination at the referring hospi- tal and was diagnosed as a lentiginous ...
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Folate Functionalized Boron Nitride Nanotubes and their Selective Uptake by Glioblastoma Multiforme Cells: Implications for their Use as Boron Carriers in Clinical Boron Neutron Capture Therapy
... provide boron selectively to tumor cells and would be nontoxic to normal ...of boron delivery by BNCT agents to cancer and normal cells [10, ...several boron agents have been proposed and ...
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A History of 20th-Century Boron Neutron-Capture Therapy
... Moritz Goldhaber was an undergraduate student of theoretical physics at Berlin University in January, 1933, when the Nazis seized power in Germany. Goldhaber asked for and received recommendations from his renowned ...
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Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy
... Two different tumor models were used for investigating the biodistribution: CT26.WT colon carcinoma (in BALB/c mice) and SCCVII murine squamous cell carcinoma (in C3H mice). The liposomes consisted of the boron ...
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