Brown adipose
Cold induced changes in gene expression in brown adipose tissue, white adipose tissue and liver
... tissue, brown adipose tissue (BAT) which is activated by the sympathetic nervous system during cold exposure and produces heat as a result of the BAT-specific expression of uncoupling protein 1 (UCP-1) ...
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Recruited brown adipose tissue as an antiobesity agent in humans
... Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography and computed tomography, we ...
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Histone Deacetylase 3 And The Epigenomic Regulation Of Brown Adipose Physiology
... in brown fat would help further elucidate its surprising activator function in brown ...in brown adipose tissue has unappreciated coregulatory interactors which help facilitate the unique and ...
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Novel insights in imaging and function of human brown adipose tissue
... white adipose tissue (WAT), which stores excess energy, brown adipose tissue (BAT) dissipates chemical energy in the form of heat by uncoupling oxidative phosphorylation from electron transport ...
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Exercise induced adaptations to white and brown adipose tissue
... on adipose tissue and the effects that these exercise-induced adaptations have on overall metabolic ...white adipose tissue (WAT) and brown adipose tissue (BAT) has revealed marked differences ...
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Norepinephrine as a morphogen?: its unique interaction with brown adipose tissue
... Int J Dev BioI 39 827 837 (1995) Norepinephrine as a morphogen? its unique interaction with brown adipose tissue JAN NEDERGAARD*, DAVID HERRON, ANDERS JACOBSSON, STEFAN REHNMARK and BARBARA CANNON The[.] ...
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Hormonal regulation of the glycerolipid synthesis pathway in brown adipose tissue
... Adrenalectomy resulted in increased mitochondrial GPAT activity in BAT from warm-adapted rats which mimicked the effect of 3-days cold-exposure. Cold-exposure of the adrenalectomized rats did not further elevate the ...
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Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue
... Interscapular brown adipose tissue (IBAT) is the main site of non-shivering thermogenesis [1]. The thermogenic capacity of IBAT relies on its high mitochondrial density and unique presence of uncoupling ...
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Glucocorticoids modulate human brown adipose tissue thermogenesis in vivo
... BAT, brown adipose tissue; CRF, clinical research facility; DXA, dual energy x-ray absorptiometry; HC, hydrocortisone; HOMA, homeostatic model assessment; ISO, isoprenaline; IT, infrared thermography; NEFA, ...
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Identification and characterization of a supraclavicular brown adipose tissue in mice
... thermoactive brown adipocytes within brown adipose tissue (BAT). Brown adipocytes contain multiple small lipid droplets, are densely packed with mitochondria, and express high levels of ...
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Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice
... white adipose tissue (WAT), brown adipose tissue (BAT), the brain, and liver but reduced it in the quadriceps ...increased adipose TG lipase content in white adipose tissue, while ...
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On Novel Features of the Proton Leak and Possibility of Uncoupling Population of Mitochondria in Brown Adipose Tissue
... Thermogenesis is an important part of the metabolism of many tissues, including that of beige fat, but especially intensively in brown adipose tissue [1-3]. It may be the result of different substrates ...
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Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
... Brown adipose tissue (BAT) is known to function in the dissipation of chemical energy in response to cold or excess feeding, and also has the capacity to modulate energy ...white adipose tissue ...
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Brown Adipose Tissue Responds to Cold and Adrenergic Stimulation by Induction of FGF21
... and adipose tissue. Brown adipose tissue (BAT) is responsible for cold-induced thermo- genesis in ...a brown adipocyte cell line were used to explore the potential role of cold exposure and β ...
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Determination of a pharmacokinetic model for [11C]-acetate in brown adipose tissue
... Excess weight is a well-known risk factor for many disorders including diabetes and heart disease [1], but long-term weight loss proves difficult for many people [2]. Attempts are often frustrated by the decrease in ...
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Brown adipose tissue: is it affected by intermittent hypoxia?
... Exposure to IH is a model of OSA [15]. Previous reports demonstrated weight loss during exposure to constant hypoxia [16]. Our group reported [17] signifi- cant reduction in body weight and in brown adipose ...
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Nature's fat burning machine: brown adipose tissue in a hibernating mammal
... Fig. 4. Model highlighting differentially expressed genes involved in fuel utilization and heat generation in brown adipose tissue (BAT) during hibernation. The role of gene products in various metabolic ...
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INDUCTION OF BROWN ADIPOSE TISSUE: A REVIEW
... The highest threat to the adults as well as the children is obesity and overweight caused by the intake of high-calorie food and leading a deskbound way of life [1]. As the energy intake and energy expenditure are not ...
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GENETIC ANALYSIS OF BROWN ADIPOSE TISSUE, OBESITY AND GROWTH IN MICE
... Due to the automatic negative correlation between a quan- tity and its inverse (SUTHERLAND 1965), it is difficult to say whether the ob- served negative correlations [r] ...
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Recent progress in the study of brown adipose tissue
... The mesenchymal stem cell is the precursor of brown adipocytes. BAT formation occurs in the early phase of embryonic development [10]. Once it was suggested that only small mammals and new born infants possess ...
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