C-Terminal Binding Proteins
C terminal binding proteins: Emerging roles in cell survival and tumorigenesis
... genes. C- terminal binding proteins (CtBPs), which were originally identified through their binding to the Adenovirus E1A oncoprotein, have been described as such transcriptional ...
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The MTA family proteins as novel histone H3 binding proteins
... The plasmids pCDNA3-Flag-MTA1 and pcDNA3-Flag- MTA3 were kind gift from Dr. Paul Wade (NIEHS). The plasmids for pcDNA3-CHD3, pcDNA3-MTA2, pcDNA3- p66 and pcDNA3-MDB3 were kindly provided by Dr. Yi Zhang (Univ. of North ...
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Proteomic Analysis of the Kaposi's Sarcoma-Associated Herpesvirus Terminal Repeat Element Binding Proteins
... Immunofluorescence in situ hybridization analysis. Immunofluorescence as- say was performed as described previously (47). Briefly, BC-3 cells were fixed with 3% paraformaldehyde at room temperature for 10 min and ...
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Dimerization of the Papillomavirus E2 Protein Is Required for Efficient Mitotic Chromosome Association and Brd4 Binding
... E2 proteins of several papillomaviruses link the viral genome to mitotic chromosomes to ensure retention and the efficient partitioning of genomes into daughter cells following cell ...protein; proteins ...
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Transactivation, Dimerization, and DNA-Binding Activity of White Spot Syndrome Virus Immediate-Early Protein IE1
... its C terminus, and during a herpesvirus saimiri infection, this domain is required for transactivation, repression of viral proteins, and the redistribution of the host splicing factor SC-35 ...whose ...
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DNA-binding proteins that interact with the long terminal repeat of radiation leukemia virus.
... 1566-1572 0022-538X/90/041566-07$02.00/0 Copyright C 1990, American Society for Microbiology DNA-Binding Proteins That Interact with the Long Terminal Repeat of Radiation Leukemia Virus [r] ...
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An 85-kilodalton herpes simplex virus type 1 alpha trans-induction factor (VP16)-VP13/14 fusion protein retains the transactivation and structural properties of the wild-type molecule during virus infection.
... The C-terminal 79 amino acids of the herpes simplex virus regulatory protein, Vmw65, efficiently activate transcription in yeast and mammalian cells in chimeric DNA-binding proteins.. Cr[r] ...
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Characteristics and regulation of interaction of avian retrovirus pp12 protein with viral RNA.
... The Kapp was calculated from Scatchard plots for the binding of AMV or RSV Pr-C ppl2 proteins each 0.08 p.g, the amino-terminal cyanogen bromide peptide of RSV Pr-C ppl2 1.6 ,ug, or the [r] ...
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The C-Terminal Domain of ERp29 Mediates Polyomavirus Binding, Unfolding, and Infection
... The L240K mutant of ERp29 is defective in PyV unfolding and infection. Upon reaching the ER lumen, the PDI-like ER chaperone ERp29 induces a conformational change to VP1, generating a hydrophobic viral particle that ...
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The Hypervariable Domain of the Murine Leukemia Virus Surface Protein Tolerates Large Insertions and Deletions, Enabling Development of a Retroviral Particle Display System
... external proteins of enveloped viruses mediate binding to and penetration of the host ...and C-terminal sequences of SU are independent glob- ular domains (20, 35), with ...
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The Unique C Termini of Orthopoxvirus Gamma Interferon Binding Proteins Are Essential for Ligand Binding
... their C terminus (see Fig. S3 in the supple- mental material). The VACV C-terminal extension exists on all VACV isolates and one CPXV isolate (GRI), as well as RPXV (a VACV derivative ...VACV ...
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Molecular characterization and ligand binding specificity of the PDZ domain containing protein GIPC3 from Schistosoma japonicum
... GIPC proteins were relatively well conserved, in contrast to the GIPC homology 2 (GH2) domain and the flanking N- and C- terminal regions (Figure ...ligand binding spe- cificity of the PDZ ...
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Effects of an Early Conformational Switch Defect during ϕX174 Morphogenesis Are Belatedly Manifested Late in the Assembly Pathway
... C-terminal, aromatic amino acids in the X174 internal scaffolding protein B mediate conformational switches in the viral coat protein. These switches direct the coat protein through early assembly. In ...
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Distinct Mechanism for the Formation of the Ribonucleoprotein Complex of Tomato Spotted Wilt Virus
... N proteins pres- ents distinct features compared to that of other ⫺ ssRNA virus-encoded N proteins ...N proteins encoded by viruses outside the bunyavirus family according to a search in the DALI ...
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Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain
... carboxy terminal domain Since the CTD of NS4B only partially overlaps with the ER-marker, PDI ...LAMP1, proteins that resides in late endosomes and lysosomes (data not ...HCV proteins, Core, NS3 and ...
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Sortase and Sortase-Dependent Cell Surface Proteins of Probiotic and Commensal Lactobacilli.
... Prior to genome mining for SDPs, Roos and Jonsson first described the functional role of a protein in the SDP family in Lactobacillus reuteri 1063 (Roos and Jonsson, 2002). The previously uncharacterized putative cell ...
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C-Terminal Arginine Cluster Is Essential for Receptor Binding of Norovirus Capsid Protein
... protein was seen (Fig. 5A). Mass spectrometry analysis showed that these trypsin-released P polypeptides had an apparent molecular mass of 31.3 kDa (Fig. 5C; Table 3), indicating that trypsin also cleaved at the first ...
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PDZ Protein Regulation of β-arrestin Recruitment and GPCR Trafficking
... and C- terminal domains of the activated arrestin undergo a 20° rotation from the central axis and this twisting facilitates interaction with the receptor (Fig ...that binding of PDZ proteins ...
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Identification of the RNA-Binding, Dimerization, and eIF4GI-Binding Domains of Rotavirus Nonstructural Protein NSP3
... RNA binding properties of NSP3. Most often, RNA binding proteins interact with RNA targets which contain various secondary structures as stem- loops, pseudoknots, bulges, and three-dimensional shapes ...
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Issues in Patterning Self-Assembled Monolayers by Molecular Replacement: Comparison of Adventitious and Directed Replacement of One Molecule in a SAM with Another.
... proposed c(4 × 2) superlattice structure of an alkanethiol SAM on gold where wedges indicate the tilt direction of the chains and dark circles indicate the sulfur ...the c(4 × 2) structure and the large ...
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