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C-type lectin domains

In silico analysis of C-type lectin domains’ structure and properties

In silico analysis of C-type lectin domains’ structure and properties

... Chapter 4 Structure comparison including theoretical models: 1afa, 1afb, 1afd, 1b08, 1b6e, 1bch, 1bcj, 1bcp, 1bj3, 1buu, 1bv4, 1byf, 1c3a, 1cwv, 1dv8, 1e5u, 1e87, 1e8i, 1egg, 1egi, 1esl, 1f00, 1f02, 1fif, 1fih, 1fm5, ...

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Myeloid dendritic cells display downregulation of C type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus

Myeloid dendritic cells display downregulation of C type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus

... the C-type lectin receptors ...more C-type lectin domains, and may bind carbohy- drate moieties in a calcium-dependent manner ...

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Immune-related Lectin-like Receptors in Zebrafish Innate Immunity

Immune-related Lectin-like Receptors in Zebrafish Innate Immunity

... (1). C-type lectin receptors represent a large superfamily of lectins that recognize carbohydrates through a highly folded carbohydrate recognition domain (CRD) in a calcium-dependent ...encoding ...

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Localization and characterization of C type lectin like family of proteins in Leptospira interrogans

Localization and characterization of C type lectin like family of proteins in Leptospira interrogans

... Hypothetical proteins (LIC12315, 12690, 12906, 13006, 13248, 13296 and 13467) were selected from the L. interrogans serovar Copenhageni genome based on the predicted value of their potential coiled coil domains, ...

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Targeting CLL-1 for acute myeloid leukemia therapy

Targeting CLL-1 for acute myeloid leukemia therapy

... of C-type lectin-like receptor ...a type II transmembrane glyco- protein, consisting of a single extracellular carbohydrate recognition domains with 6 N-glycosylation sites, a trans- ...

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Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors

... We sought to identify candidate receptors that might be involved in MBL-enhanced EBOV infection. We used short hairpin (sh)RNA-expressing lentiviral constructs to knock down expression of 24 candidate lectin, ...

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Identification and preliminary characterization of Hc clec 160, a novel C type lectin domain containing gene of the strongylid nematode Haemonchus contortus

Identification and preliminary characterization of Hc clec 160, a novel C type lectin domain containing gene of the strongylid nematode Haemonchus contortus

... factors B, C2, CR3 and CR4; the integrins (I-domains); col- lagen types VI, VII, XII and XIV; and other extracellular proteins [19, 20]. Most of the proteins containing vWF do- mains are exocrine. The ...

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Phylogenetic Analysis of C Type Lectin from Toxocara canis  Infective Larvae and Comparison with the C Type Lectin Fam-ily in the Immune System of Mouse and Human

Phylogenetic Analysis of C Type Lectin from Toxocara canis Infective Larvae and Comparison with the C Type Lectin Fam-ily in the Immune System of Mouse and Human

... of C type lectin and collagen ...consists C type lec- tins which act as receptor-mediated endocyto- sis, and include the asialoglycoprotein receptor (ASGPR), the macrophage mannose ...

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Cloning and characterization of a mannose binding C type lectin gene from salivary gland of Aedes albopictus

Cloning and characterization of a mannose binding C type lectin gene from salivary gland of Aedes albopictus

... a C-type lectin ( AaegmosGCTL-1 ) induced by West Nile Virus (WNV) infection, can interact with WNV in a calcium- dependent manner, and facilitate flavivirus invasion in vivo and in vitro ...

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Tumor therapy in mice via antigen targeting to a novel, DC restricted C type lectin

Tumor therapy in mice via antigen targeting to a novel, DC restricted C type lectin

... drate-recognition domains (Supplemental Figures 1 and ...intracellular domains with CLEC9A but would have a short and distinct extracellular ...cell lectin receptor I (KLR-I) ...of ...

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Evolutionary relationships and expression analysis of EUL domain proteins in rice (Oryza sativa)

Evolutionary relationships and expression analysis of EUL domain proteins in rice (Oryza sativa)

... (OsEULD1A), LOC_Os03g21040.2 (OsEULD1B), and LOC_Os07g48460.1 (OsEULD2) sequences, using the X- ray coordinates of different bacterial hydrolases and lec- tins as templates: a β-l-arabinopyranosidase from Strep- tomyces ...

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The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains

The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains

... Almost all known CTLDs have a ␤ -sheet composed of the ␤ 2, ␤ 3, and ␤ 4 strands located immediately N-terminal to the ␤ 5 strand at the C terminus. But A33 is different and to our knowledge unique. Starting at ...

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Composition, Structure, Dynamics and Function of C-Type Lectin Receptor Domains

Composition, Structure, Dynamics and Function of C-Type Lectin Receptor Domains

... containing domains, cells were stained with DC-SIGN using DCN46 and goat anti-mouse-Alexa488 secondary ...membrane domains in areas containing (left) or not containing (right) a DC-SIGN ...4.5 C ...

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High Bacterial Agglutination Activity in a Single-CRD C-Type Lectin from Spodoptera exigua (Lepidoptera: Noctuidae)

High Bacterial Agglutination Activity in a Single-CRD C-Type Lectin from Spodoptera exigua (Lepidoptera: Noctuidae)

... Abstract: Lectins are carbohydrate-interacting proteins playing a pivotal role in multiple physiological and developmental aspects of all organisms. They can specifically interact with different bacterial and viral ...

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Characterization of Caenorhabditis elegans lectin-binding mutants.

Characterization of Caenorhabditis elegans lectin-binding mutants.

... (Because surface lectin binding is restricted to small regions of the adult wild-type animal, mutants missing this lectin binding are difficult to identify in a dissecting micro- sc[r] ...

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An in vitro study of dendritic cell development from precursors

An in vitro study of dendritic cell development from precursors

... Protein Type of protein Putative function Target DC population Reference cell Reference population 1 name CIRE Type II C-type lectin T cell interaction, migration Murine CD8a- DC Murine [r] ...

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C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map

C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map

... encoding C-type lectin receptors and RIG-I-like receptors and cancer risk or ...of C-type lectin receptors and RIG-I-like receptors were only obtained in the last few years, 3,4 ...

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mosGCTL-7, a C-Type Lectin Protein, Mediates Japanese Encephalitis Virus Infection in Mosquitoes

mosGCTL-7, a C-Type Lectin Protein, Mediates Japanese Encephalitis Virus Infection in Mosquitoes

... Arthropod-borne microbes induce zoonoses around the world, and mosquito con- trol is a primary ameliorating strategy (65). In malaria studies, transmission-blocking vaccines (TBVs) had been reported by several ...

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Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells

Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells

... FACS analyses. One million cells were incubated with antibodies (1 ␮ g) in 500 ␮l of PBS containing 0.25% human serum. Anti-CD4 SIM.4 immunoglobulin G1 (IgG1) (generously contributed by James Hildreth), anti-DC-SIGN DC28 ...

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Lachesis muta (Viperidae) cDNAs Reveal Diverging Pit Viper Molecules and Scaffolds Typical of Cobra (Elapidae) Venoms: Implications for Snake Toxin Repertoire Evolution

Lachesis muta (Viperidae) cDNAs Reveal Diverging Pit Viper Molecules and Scaffolds Typical of Cobra (Elapidae) Venoms: Implications for Snake Toxin Repertoire Evolution

... cules not very divergent from previously known ones. Conversely, LMUT0114C is a medium-abundant cluster that unusually shows identities at the same low level (34%) to snake and nonsnake lectins, including a different Cys ...

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