C57BL/6J
Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice
... in C57BL/6J mice and that specific predisposing muta- tions [57] or carcinogenic agents [58,59] are required to induce colorectal cancer in this mouse ...
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Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J
... only C57BL/6J, since all C57 strains in the database (C57BL/10J, C57BL/6NJ, C57BR/cdJ, and C57L/J) have the same substitution as well as BUB/BnJ, NZB/B1NJ, and ...Furthermore, ...
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THE GENETIC CONTROL OF THREE KIDNEY ESTERASES IN C57BL/6J AND RF/J MICE
... Three kidney esterases, two of which are native to RF/J mice (esterases A and B) and one which is native to C57BL/6J (C esterase) have been distinguished by vertical starc[r] ...
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Associations between basal metabolic rate and reproductive performance in C57BL/6J mice
... Female C57BL/6J mice (N=304) were purchased in three batches from Harlan UK Ltd, Oxon, UK, at 6·weeks of age, and were housed in groups of six in a 12·h:12·h light:dark photoperiod at approximately 23°C, ...
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The Effects of a High Fat Diet Containing Diacylglycerol on Bone in C57BL/6J Mice
... male C57BL/6J mice (n=39) were divided into three weight-matched groups based on diet type: a chow diet group, a HFD containing TAG (HFD-TAG) group, and a HFD-DAG ...in C57BL/6J ...
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Activation of Invariant Natural Killer T Cell Subsets in C57BL/6J Mice by Different Injection Modes of α-galactosylceramide
... study, C57BL/6J mice were injected with α-GalCer subcutaneously and intraperitoneally to observe the changes in the frequency, subset proportion, and function of iNKT cells in the thymus, liver, and ...
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Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
... Committee (IACUC) and all animal procedures were approved by Beijing Administration Office of Laboratory Animal (approval number: SCXK-Beijing- 2009-0004). All efforts were made to minimize suffering. Six- to eight- ...
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Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice
... This study was completed under UK Home Office project licence PPL 60/3951 and approved by the University of Aberdeen Ethics Review Board. 10-month-old male C57BL/6J wild-type mice (Charles River, Edinburgh, ...
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Nobiletin Prevents Body Weight Gain and Bone Loss in Ovariectomized C57BL/6J Mice
... Female C57BL/6J mice were purchased from Japan SLC (Shizuoka, Japan) at 6 weeks of age. The mice were housed under temperature—(23 ˚C ± 3˚C) and humidity-controlled conditions with a 12-h light/dark cycle, ...
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The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice
... to C57BL/6j mice during this phase of movement, suggesting some late hepatic/post-hepatic/early pulmonary factor that varies between the 2 strains preventing further ...
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Curcumin and an antioxidant formulation protect C57BL/6J mice from MPTP-induced Parkinson’s disease like changes: potential neuroprotection for neurodegeneration
... Figure 1 The effect of postnatal PBS (c1), MPTP (c2), MPTP + cUR (c3 and c4) and MPTP + aOF (c5 and c6) treatments on motor activities in c57BL/6J mice. Notes: Measures were made 24 hours after the last ...
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Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age
... with C57BL/6J ...JAX C57BL/6J strain or C57BL/6J substrains (6JJcl or 6JJmsSlc) maintained in Japan, were regarded as “C57BL/6J” ...
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Limited impact of Cntn4 mutation on autism-related traits in developing and adult C57BL/6J mice
... Hyperresponsivity to acoustic stimuli is related to many neurodevelopmental disorders and has also been reported in ASD [22]. In addition, acoustic hyperrespon- sivity in patients with fragile X syndrome is known to be ...
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C57BL/6J mouse model of non insulin dependent diabetes mellitus
... / 6J mouse model of II-type diabetes induced by High-fat diet and STZ is numerously studied in recent years, which is regarded as an ideal animal model of II-type ...diabetes. C57BL/6J mice, which ...
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Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
... the C57BL/6J inbred strain used for ...of C57BL/6J mice, namely animals from ...strain C57BL/6S. C57BL/6S animals appear phenotypically ...
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Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans
... female C57BL/6J (B6) mice significantly reduced plasma glucose, cholesterol, triglycerides and body weight, while elevating fatty acids and ketone ...
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Inflammatory stress exacerbates ectopic lipid deposition in C57BL/6J mice
... Chronic systemic inflammation plays an important role in pathogenesis of multiple metabolic disorders, includ- ing insulin resistance, T2DM, NAFLD, atherosclerosis, obesity and dyslipidemia [15,16]. In this study, we use ...
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Establishment and characterization of a sustained delayed type hypersensitivity model with arthritic manifestations in C57BL/6J mice
... in C57BL/6 mice with synchronized onset and progression and high incidence displaying severe bone and cartilage destruction, something that presents difficulties in the CAIA [15] and CIA [36,37] models when using ...
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Spontaneous Mutations in Recombinant Inbred Mice: Mutant Toll-like Receptor 4 (Tlr4) in BXD29 Mice
... The disruption of Tlr4 in BXD29 mice provides a ready explanation for their lack of an innate immune response to inhaled LPS, but the actions of this receptor are not limited to its function in innate immune responses. ...
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PubMedCentral-PMC5633391.pdf
... and C57BL/6J · A/J) and chromosome substitution strain panels (C57BL/6J-Chr# , A/J ..., C57BL/6J-Chr# , PWD/Ph . , and C57BL/6J- ...
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