C57BL/6J mice
Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age
... in C57BL/6J mice by taking advan- tage of a large amount of behavioral data that we had collected through a behavioral test battery applied to many mutant strains of ...the C57BL/6J ...
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Inflammatory stress exacerbates ectopic lipid deposition in C57BL/6J mice
... in C57BL/6J mice fed with NCD or HFD to investigate if inflammation causes ectopic lipid deposition in nonadipose ...in C57BL/6J ...
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Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice
... in C57BL/6J mice is characterized by different ...years. Mice are considered to be in their old phase when they are between 18 and 24 months of age repre- senting a human age ranging from 56 ...
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Associations between basal metabolic rate and reproductive performance in C57BL/6J mice
... In this study, we set out to characterise the relationship between fecundity and BMR measured after weaning in C57BL/6J mice. Associations between individual variations in BMR and reproductive ...
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Curcumin and an antioxidant formulation protect C57BL/6J mice from MPTP-induced Parkinson’s disease like changes: potential neuroprotection for neurodegeneration
... Figure 1 The effect of postnatal PBS (c1), MPTP (c2), MPTP + cUR (c3 and c4) and MPTP + aOF (c5 and c6) treatments on motor activities in c57BL/6J mice. Notes: Measures were made 24 hours after the ...
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Activation of Invariant Natural Killer T Cell Subsets in C57BL/6J Mice by Different Injection Modes of α-galactosylceramide
... study, C57BL/6J mice were injected with α-GalCer subcutaneously and intraperitoneally to observe the changes in the frequency, subset proportion, and function of iNKT cells in the thymus, liver, and ...
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Corticosterone and dopamine D2/D3 receptors mediate the motivation for voluntary wheel running in C57BL/6J mice
... treated C57BL/6J mice acutely with the inhibitor of corticosterone synthesis metyrapone (35 mg/kg) or repeatedly with the GR antagonist mifepristone (30 mg/kg) prior to 1-hour running wheel ...
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Nobiletin Prevents Body Weight Gain and Bone Loss in Ovariectomized C57BL/6J Mice
... Female C57BL/6J mice were purchased from Japan SLC (Shizuoka, Japan) at 6 weeks of ...The mice were housed under temperature—(23 ˚C ± 3˚C) and humidity-controlled conditions with a 12-h ...
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Study on administration of 1,5-anhydro-D-fructose in C57BL/6J mice challenged with high-fat diet
... of C57BL/6J mice as a model to investigate the effect of long-term administration of AF on glucose-stimulated insulin secretion in vivo and in ...vitro. C57BL/6J mice ...
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Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
... female C57BL/6J mice were purchased from HFK Bioscience Laboratories (Beijing, ...All mice were maintained under SPF conditions and 12 h light/ dark cycle at 23 ± 2 °C, with free access to ...
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The Effects of a High Fat Diet Containing Diacylglycerol on Bone in C57BL/6J Mice
... in mice. Materials and Methods: Four-week-old male C57BL/6J mice (n=39) were divided into three weight-matched groups based on diet type: a chow diet group, a HFD containing TAG (HFD-TAG) ...
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Effects of neonatal inhalation exposure to ultrafine carbon particles on pathology and behavioral outcomes in C57BL/6J mice
... Background: Recent epidemiological studies indicate early-life exposure to air pollution is associated with adverse neurodevelopmental outcomes. Previous studies investigating neonatal exposure to ambient fine and ...
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Establishment and characterization of a sustained delayed type hypersensitivity model with arthritic manifestations in C57BL/6J mice
... in mice with delayed-type hypersensitivity (DTH) ...cartilage. Mice with DTH arthritis developed severe arthritis characterized by increased cartilage degradation (as assessed by loss of Safranin O ...
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Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice
... MR-fed mice had significantly higher levels of phosphorylation of mTOR compared to both control and LR-fed mice and LR-fed mice trended towards higher levels of phosphorylation of mTOR relative to ...
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Limited impact of Cntn4 mutation on autism-related traits in developing and adult C57BL/6J mice
... We thank Y. Yoshihara for the generous gift of Cntn4 -deficient mice, M. Brandt for the help with the three-chamber sociability test, H. Oppelaar and M. Broekhoven for the technical assistance, and A. Oguro-Ando ...
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TLR2 signal influences the iNOS/NO responses and worm development in C57BL/6J mice infected with Clonorchis sinensis
... Toll-like receptors (TLRs) are transmembrane proteins that recognize pathogen-associated molecular patterns (PAMPs) of multiple pathogens, including bacteria, viruses, fungi and parasites [14, 15]. The TLR family is ...
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Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans
... female C57BL/6J (B6) mice (n = 4/group) were fed a standard rodent chow diet either: (1) unrestricted (UR); (2) restricted for three weeks to reduce body weight by approximately 15–20% (R); or (3) ...
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Differential Interstrain Susceptibility to Vertebrobasilar Dolichoectasia in a Mouse Model
... that C57BL/6J mice are markedly more susceptible to VBD induction than SV129 ...most C57BL/6J mice achieved our prespecified threshold for VBD induction but none of the SV129 ...
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The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice
... CBA/Ca mice in contrast to C57BL/6j mice during this phase of movement, suggesting some late hepatic/post-hepatic/early pulmonary factor that varies between the 2 strains preventing further ...
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Original Article Primary culture and adenoviral infection of adult mouse knee articular chondrocytes: a new tool for investigating cartilage
... Abstract: Object: To establish a method for primary culture and gene manipulation with adenoviral infection of chondrocytes from knee articular cartilage of adult mice (C57BL/6J). Significant ...
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