Calcium Signalling
Atherosclerosis differentially affects calcium signalling in endothelial cells from aortic arch and thoracic aorta in Apolipoprotein E knockout mice.
... fewer signalling dif- ferences in the plaque-resistant thoracic ...of calcium signalling pathways in the development of atherosclerosis has been previously ...the calcium signalling ...
15
Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII
... This study reports transcriptional and functional approaches to defining the molecular responses of schistosomes to PZQ. We demonstrate the functionally utility of the xCELLigence system to provide real time assessment ...
11
Assessment of CXC ligand 12 mediated calcium signalling and its regulators in basal like breast cancer cells
... calcium signalling may be influenced by CXCR4, CXCR7 and CD24 (7,13), and that their expression differed between the more epithelial MDA‑MB‑468 (basal A) and the more mesenchymal MDA‑MB‑231 (basal B) breast ...
7
Homer regulates calcium signalling in growth cone turning
... store-operated calcium entry include the TRPC family of cation channels and the Orai-STIM1 complex ...filopodial calcium transients, which are crucial to the spatial and temporal regulation of ...
19
Organellar calcium signalling mechanisms in Drosophila epithelial function
... into calcium signalling has been an intensive area of investigation for some decades, and current known mechanisms of calcium signalling in many cell types, notably neuronal, endothelial and ...
14
Boolean calcium signalling model predicts calcium role in acceleration and stability of abscisic acid-mediated stomatal closure
... Considering the emerging understanding that the timing is more crucial than the exact level of proteins, we believe that the system dynamics revealed by our model is a closer qualitative approximation of the real system ...
16
Modelling and investigation of NMDAR-mediated calcium signalling at Hippocampal Dendritic Spine in Alzheimer’s disease
... However, unlike FAD, causes of SAD are much more complex, involving both genetic and environmental risk factors. Therefore, it remains a great challenge to study the key factors in SAD (Young and Goldstein 2012). ...
236
Sense and specificity in neuronal calcium signalling
... fundamental signalling ion being used to produce a variety of subtle and distinct ...of signalling [17, ...distinct signalling pathways to changes in gene expression ...
41
Specific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cells
... neuronal calcium sensor (NCS) proteins consisting of NCS-1, neurocalcin δ, hippocalcin, VILIPs1-3, recoverin, GCAPs1-3 and the K + channel interacting proteins (KChIPs)1-4 [2, ...
25
Atherosclerosis and calcium signalling in endothelial cells
... Depletion of the internal stores appears to stimulate influx of Ca2 + into the cell via plasma membrane ion channels a process known as capacitative Ca2+ entry Putney et al., 2001, and c[r] ...
27
Elementary and global aspects of calcium signalling
... membrane display similar elementary events such as the bumps in Drosophila receptors (Hardie, 1991) or the quantum emission domains (QEDs) in squid giant synapses (Sugimori et al. 1994). Attention is now focused on how ...
5
Calcium signalling and buffering: The role of annexin VI
... Annexin VI has been implicated in both endo- and exocytosis since, like all the annexins, it binds phospholipids in a calcium dependent fashion (Lu, Bazzi and Nelsestuen, 1995). The protein is predominantly ...
202
Two pore channels and NAADP dependent calcium signalling
... whereby cADPR is potentially synthesised extracellularly, only to then mobilise Ca 2+ via interaction with its intracellularly located receptor (De Flora et al., 2000). A solution to this paradox was proposed by De Flora ...
303
Single cell mechanics and calcium signalling in organotypic slices of human myometrium
... proportion of cells and quickly disappear, while augmentation of contractility in the presence of oxytocin persists for much longer. Our fi ndings are compatible with the idea that myometrial con- tractions are regulated ...
6
The protein kinase Cmk2 negatively regulates the calcium/calcineurin signalling pathway and expression of calcium pump genes PMR1 and PMC1 in budding yeast
... identified calcium-tolerant deletion mutants for five genes in the budding yeast Saccharomyces cerevisiae ...the calcium signalling pathway, the protein kinase gene CMK2 , the sphingolipid ...
9
Yeast stress signalling
... I have begun an exam ination of repressive inputs to several stress response genes in S.pombe. The observed repressive effects on S ty l/A tfl dependent genes had both sim ilarities and differences w ith gene control m ...
218
The Interplay between Hedgehog Signalling and BMP Signalling in Regulating B cell Development
... BMP signalling are required to take place for these early events in B cell activation and that the synergy requires BMP signalling to take place downstream in order to mediate its ...Hh signalling ...
78
Modelling religious signalling
... the signalling system framework extremely ...to signalling systems and the stability of signalling behaviour (Skyrms ...the signalling system ...
250
Purinergic signalling in skin
... In contrast, high concentrations of ATP and the P2X? receptor agonist, BzATP caused a significant decrease in A431 cell number (P<0.001). P2X? receptors were heavily expressed in the necrotic centre of nodular basal ...
306
JAK/STAT signalling
... IL-6 signalling to JAKl-deficient U4C cells was investigated by EMSv^nalysis of transierîtly transfected cells ...residual signalling mediated by JAK2 and Tyk2 in the absence of JAKl (Guschin, Rogers et ...
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