Candida Glabrata
Genomewide Expression Profile Analysis of the Candida glabrata Pdr1 Regulon
... transporters Candida glabrata Cdr1 (CgCdr1), CgPdh1, and CgSnq2 are known to mediate azole resistance in the pathogenic fungus ...C. glabrata clinical isolate ...
11
Microsatellite Marker Analysis as a Typing System for Candida glabrata
... though Candida albicans remains the main species, Candida glabrata is the second leading species recovered from blood cultures in Europe and in the United States (20, 28), especially in intensive ...
6
Inactivation of Transcription Factor Gene ACE2 in the Fungal Pathogen Candida glabrata Results in Hypervirulence
... For Candida species, the inactivation of many fungal attributes has been shown to result in ...the Candida glabrata homolog of the Saccharomyces cerevisiae transcription factor gene ACE2 encodes a ...
7
Candida glabrata Has No Enhancing Role in the Pathogenesis of Candida-Associated Denture Stomatitis in a Rat Model
... wearers. Candida-associated DS is predominantly caused by Candida albicans, a dimorphic fungus that readily colonizes and forms biofilms on denture ...for Candida biofilm forma- tion on both palate and ...
9
Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata
... of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive ...C. glabrata to fluconazole, we screened a collection of deletion mu- tants for those exhibiting ...
11
Evaluation of Polymorphic Locus Sequence Typing for Candida glabrata Epidemiology
... yeast Candida glabrata is increasingly refractory to antifungal treatment or prophylaxis and relatedly is in- creasingly implicated in health care-associated ...C. glabrata that targets polymorphic ...
9
Subtelomeric Silencing of the MTL3 Locus of Candida glabrata Requires yKu70, yKu80, and Rif1 Proteins
... C. glabrata containing 5 URA3 insertions throughout the MTL1 locus (B), 7 in the MTL2 locus (C), or 10 in the MTL3 locus (D) were grown to stationary phase in YPD, and 10-fold serial dilutions in sterile water ...
10
Chromatin Loop Formation Induced by a Subtelomeric Protosilencer Represses EPA Genes in Candida glabrata
... Transcriptional silencing is propagated from the telomere to the centromere, spanning the subtelomeric regions. Genes naturally located in the subtelomeric region are repressed in a promoter-independent fashion, although ...
16
Techniques for investigation of an apparent outbreak of infections with Candida glabrata
... of Candida glabrata isolates recovered from seven patients in an intensive care unit over a 10-week period were compared with a collection of isolates from six epidemiologically distinct outpatients and a ...
5
Candida glabrata endophthalmitis following penetrating keratoplasty in a patient with negative donor rim culture
... In conclusion, Candida glabrata endophthalmitis is uncommon but a potentially devastating complication following penetrating keratoplasty. A complete work-up is essential to identify the source of infection ...
5
Cellular apoptosis: An alternative mechanism of action for caspofungin against Candida glabrata
... C. glabrata strain under both caspofungin-treated and -untreated ...Briefly, Candida glabrata cells were treated with ...C. glabrata cells, the test was performed in 24- well ...C. ...
7
Three Mating Type-Like Loci in Candida glabrata
... Candida glabrata, the second most prevalent Candida species colonizing humans, possesses three mating type-like (MTL) loci (MTL1, MTL2, and ...C. glabrata strains were either aa ␣ or a ␣␣ ...
13
Mitochondrial fusion and fission are involved in stress tolerance of Candida glabrata
... Candida glabrata, a haploid multivitamin auxotrophic yeast, is an important strain used for industrial production of pyruvate [17] and α-ketoglutaric acid ...C. glabrata was also used to produce ...
9
yKu70/yKu80 and Rif1 Regulate Silencing Differentially at Telomeres in Candida glabrata
... Candida glabrata, a common opportunistic fungal pathogen, adheres efficiently to mammalian epithelial cells in ...C. glabrata orthologues of known regulators of subtelomeric silencing in ...
11
Mitochondrial DNA Heteroplasmy in Candida glabrata after Mitochondrial Transformation
... yeast Candida glabrata (Torulopsis glabrata) is the yeast species most similar to ...C. glabrata is a common Can- dida pathogen, second only to ...C. glabrata strains are commonly used ...
9
Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in Candida glabrata
... diseases. Candida glabrata is a pathogenic yeast that is increasingly found associated with bloodstream infections, a finding likely contributed to by its proclivity to develop azole drug ...C. ...
20
Antifungal activity of the rhizome extracts of Pulsatilla vulgaris against Candida glabrata
... ABSTRACT: Pulsatilla vulgaris Mill. (“Pasque flower”, Ranunculaceae) is rare and a threatened plant species in Europe. It produces biologically active secondary metabolites. P. vulgaris is also known herbal drug used for ...
11
Inner Kinetochore of the Pathogenic Yeast Candida glabrata
... yeast Candida glabrata is the second most common Candida pathogen after Candida albicans, causing both bloodstream and mucosal ...C. glabrata (CgCEN), although structurally very similar ...
10
Candida Glabrata: An emerging threat for the Immunocompromised
... of Candida albicans but it is not the only species that causes infections in humans, whether superficial or ...recently, Candida glabrata has been considered as a non- pathogenic saprophyte rarely ...
5
Mutants in the Candida glabrata Glycerol Channels Are Sensitized to Cell Wall Stress
... that Candida glabrata, a fungal pathogen that possesses two Fps1 orthologs and two Rgc1/-2 or- thologs, accumulates glycerol in response to hyperosmotic ...C. glabrata FPS1 (CAGL0C03267 ...C. ...
8