Candidate Gene Case-Control SNP Association Study
Variation in endoglin pathway genes is associated with preeclampsia: a case–control candidate gene association study
... In addition to sample size, there are other limitations to our study. Multiallelic tSNPs rs8179181 (TGFβ1) and rs3087465 (TGFβR2) could not be genotyped despite multiple attempts with iPLEX W and TaqMan W , which ...
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Candidate Gene Association Study for Diabetic Retinopathy in Persons with Type 2 Diabetes: The Candidate Gene Association Resource (CARe)
... of study inclusion but are at risk for significant DR with longer duration of ...an association with EPO indicates that the amount of control misclassification in CARe is not significant enough to ...
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Association of candidate gene polymorphisms and TGF beta/IL 10 levels with malaria in three regions of Cameroon: a case–control study
... the association between HbS rs334 and ADCY9 rs2230739 with plasma levels of transforming growth factor-beta as well as ABO rs8176746 with interleukin-10 is quite interesting since resistance to severe malaria has ...
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Powerful SNP-Set Analysis for Case-Control Genome-wide Association Studies
... a SNP-set formation strategy that optimizes for this can be ...a gene or moving-window strategy can certainly capture multi-SNP and epistatic effects among SNPs that are located close to one another ...
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A Candidate Gene Association Study of Bone Mineral Density in an Iranian Population
... this study is a substantial contribution to the genetic epidemiology of variation in BMD in the Iranian population, it does have ...the study is powered to detect larger effects but limits the potential for ...
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Polymorphisms of the endothelial nitric oxide synthase (NOS3) gene in preeclampsia: a candidate gene association study
... the association of three common variants of the NOS3 gene (4b/a, T-786C and G894T) and their haplotypes in a case-control sample of 102 patients with preeclampsia and 176 women with a history ...
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MBL2 Gene Polymorphism and the Association with Neonatal Sepsis in Egyptian Neonates, a Case Control Study
... this study we use multiplex PCR which considered as a fast and inexpensive method for the detection of specific DNA ...the gene, which is the case of MBL2 genotyping. In this study, the most ...
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Association of the 5HTR2A gene with suicidal behavior: CASE control study and updated meta analysis
... in case – control and meta-analysis studies, but results and conclusions remain ...present study was to examine the association between T102C with suicidal behavior in a case – ...
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Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study
... in candidate gene studies may not be replicated in GWA studies, due to suboptimal representation and coverage of the risk var- iants with the tag SNPs used in the high-throughput platforms ...
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A case control genome wide association study of ADHD discovers a novel association with the tenascin R (TNR) gene
... this candidate gene literature 8,9 , a key limitation remains the a © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution ...
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On the identification of potential regulatory variants within genome wide association candidate SNP sets
... specific case study from a meta-analysis of lung cancer GWAS ...specific SNP with interesting cancer-related characteristics (Additional files 10 and ...The SNP rs12087869 from the ...receptor ...
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The association between TNP2 gene polymorphisms and Iranian infertile men with varicocele: A case-control study
... this SNP (rs8043625) in varicocele patients may affect in intron splicing and may cause human male infertility in varicocele patients, but the exact molecular effects of this polymorphism on varicocele condition ...
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Association of vitamin D receptor gene variants with polycystic ovary syndrome: A case control study
... The present study has several limitations. A limitation of the present study is its sample size. Considering the small sample size, the genotype differences may be attributable strictly to chance. Another ...
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Original Article Association of CYP1A1 gene polymorphism and susceptibility to lung cancer: a case-control study
... Moreover, heavy haze in China, has increased the risk of developing lung cancer in recent years [1, 2]. In the light of the malignancy cases structure in China over the past decade, lung cancer accounts for 22.7% of all ...
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Further evidence for the association of CYP2D6*4 gene polymorphism with Parkinson’s disease: a case control study
... Anwarullah 1,3,4 † , Muhammad Aslam 1,2 † , Mazhar Badshah 5 , Rashda Abbasi 4 , Aneesa Sultan 3 , Kafaitullah Khan 6 , Nafees Ahmad 4 † and Jakob von Engelhardt 1,2* † Abstract Background: Genetic and environmental risk ...
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The association of vitamin D receptor gene polymorphisms and acute myeloid leukemia: a case-control study
... VDR gene polymorphisms and cancers are ...the association between common VDR gene polymorphisms (FokI, BsmI, TaqI, ApaI and Cdx2) and the risk of different solid tumors in the skin, prostate, breast, ...
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Association of NOS1 gene polymorphisms with cerebral palsy in a Han Chinese population: a case-control study
... Nitric oxide (NO) acts as a pleiotropic gaseous mes- senger molecule, and it is dynamically controlled during normal development and brain injuries. NO is synthe- sized from L-arginine by nitric oxide synthase enzymes ...
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Candidate gene based association study for nitrogen use efficiency and associated traits in maize
... and association analysis DnaSp Version 4 (Rozas et ...among candidate genes based on the SNPs in the amplified fragment sequences of the AS ...101 SNP markers distributed evenly across the maize ...
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Sequence variants in oxytocin pathway genes and preterm birth: A candidate gene association study
... common SNP genotyping data were tested for geno- type deviation from the Hardy–Weinberg equilibrium (HWE) using PLINK [19] and Haploview ...Based Association Test (FBAT) soft- ware [21,22], which analyzes ...
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Case control association analysis of rheumatoid arthritis with candidate genes using related cases
... 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci Heather J Cordell, Mariza de Andrade, Marie-Claude Babron, Christopher W Bartlett, Joseph Beyene, Heike ...
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