Cap-dependent translation
Dengue Virus Utilizes a Novel Strategy for Translation Initiation When Cap-Dependent Translation Is Inhibited
... inhibit cap- dependent translation, siRNA-mediated gene silencing was em- ployed to suppress expression of the prototypical form of mam- malian eIF4E, eIF4E-1 ...and translation resist ...
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A Viral Noncoding RNA Generated by cis-Element-Mediated Protection against 5′→3′ RNA Decay Represses both Cap-Independent and Cap-Dependent Translation
... both cap-independent translation and negative-strand RNA ...both cap-independent and cap-dependent translation both in vitro and in ...
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Activation of Cap-Dependent Translation by Mucosal Human Papillomavirus E6 Proteins Is Dependent on the Integrity of the LXXLL Binding Motif
... of cap-dependent ...enhancing cap-dependent trans- lation, we tested two HPV16 E6 mutants, Y54D and I128T, that disrupt the LXXLL binding motif and are therefore defective for E6AP binding ...
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<p>INPP4B promotes colorectal cancer cell proliferation by activating mTORC1 signaling and cap-dependent translation</p>
... activates cap-dependent translation in colon cancer ...measured. cap-dependent translational activity was determined, as described in the “Materials and methods” ...
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Alpha/Beta Interferon Inhibits Cap-Dependent Translation of Viral but Not Cellular mRNA by a PKR-Independent Mechanism
... G cap-dependent translation at a step after association of cap-binding factors and the small ribosome subunit but before formation of the 80S ...
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The 3′ Untranslated Region of the Andes Hantavirus Small mRNA Functionally Replaces the Poly(A) Tail and Stimulates Cap-Dependent Translation Initiation from the Viral mRNA
... ⬘ cap-3 ⬘ UTR interactions in Dengue virus (DENV), a member of the Flaviviridae, whose mRNA, like that of the Bunyaviridae, is capped yet lacks a poly(A) tail ...the translation of ANDV SmRNA cannot be ex- ...
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Original Article Expression of eukaryotic initiation factor 4E and 4E binding protein 1 in colorectal carcinogenesis
... Abstract: Cap dependent translation is mainly regulated at the level of the eukaryotic initiation factor 4E (eIF4E), the activity of which is controlled by phosphorylation and sequestration by its ...
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Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila
... reduce cap- dependent translation such as hypoxia, nutrient deprivation, heat stress, irradiation, infection, and ...different cap-dependent repressed translational ...
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A Small Yeast RNA Blocks Hepatitis C Virus Internal Ribosome Entry Site (HCV IRES)-Mediated Translation and Inhibits Replication of a Chimeric Poliovirus under Translational Control of the HCV IRES Element
... IRES-mediated translation both in vivo and in ...IRES-mediated cap-independent translation was markedly inhibited in cells constitutively expressing IRNA compared to control hepatoma ...However, ...
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THE WARBURG EFFECT: A POSSIBLE ROLE OF CAP INDEPENDENT TRANSLATION Ajaz Ahmad Waza*, Shabir Ahmad Bhat, Sajad AliDOWNLOAD/VIEW
... protein translation in normal and stress conditions. A) Cap dependent translation: Eukaryotic initiation factor binds to the 5’- cap on the mRNA, followed by recruitment of 40S subunit ...
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1-s2.0-S004268221930251X-main.pdf
... the cap-dependent translation of monocistronic luciferase reporters (Ziehr et ...enhances cap-independent translation we measured the effect of pTRS1 expression on the ...
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Blocking eIF4E-eIF4G Interaction as a Strategy To Impair Coronavirus Replication
... and cap-dependent translation is ...the translation of some viral sgmRNAs or mRNA encoding a cellular factor(s) required for viral rep- lication is cap dependent ...
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Translation Initiation Factor eIF4B Interacts with a Picornavirus Internal Ribosome Entry Site in both 48S and 80S Initiation Complexes Independently of Initiator AUG Location
... the cap-binding complex to the cap of cellular ...in cap-dependent translation all initiation factors dissoci- ate from the 48S complex upon joining of the large ribosomal subunit (27) ...
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Characterization of a bicistronic retroviral vector composed of the swine vesicular disease virus internal ribosome entry site.
... These data therefore suggested that insertion of the SVDV IRES in the bicistronic retroviral vector did not affect the cap-dependent translation of the first cistron; the internal initia[r] ...
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trans complementation of cap-independent translation directed by poliovirus 5' noncoding region deletion mutants: evidence for RNA-RNA interactions.
... Thus, neither the expression of PV 2A in the absence of the PV 5' NCR nor the inhibition of cap-dependent translation by the FMDV L protein appeared to be sufficient to produce the enhan[r] ...
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CUNI System for the WMT17 Multimodal Translation Task
... The challenge of the WMT Multimodal Transla- tion Task is to exploit cross-lingual information in automatic image caption generation. The state- of-the-art models in both machine translation and automatic image ...
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Financial Development, Shocks, and Growth Volatility
... the dependent variable are reported in Table ...the dependent variable, the coefficient is significantly negative for the low income countries in some specifications but its robustness does not survive when ...
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Influenza Virus mRNA Translation Revisited: Is the eIF4E Cap-Binding Factor Required for Viral mRNA Translation?
... the translation of cellular mRNAs, presenting a 30 to 35% reduction compared with the translational rate of control ...the translation of defined cellular mRNAs ...viral translation occurs normally ...
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Cap-independent enhancement of translation by a plant potyvirus 5' nontranslated region.
... The TEV 5' NTR minus the start codon was synthesized in vitro from pTL7SN.3 and added to cell-free translation reactions programmed with one of three mRNAs capped and noncapped transcrip[r] ...
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Influenza Virus Temperature-Sensitive Cap (m7GpppNm)-Dependent Endonuclease
... If the temperature sensitivity of the endonuclease is the cause of the temperature sensitivity of the overall transcription rate, then we would expect that preincubation of ts viral core[r] ...
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