capsid binding
Contribution of MxB Oligomerization to HIV-1 Capsid Binding and Restriction
... and capsid binding to the ability of MxB to block HIV-1 infection, we tested the ability of MxB variants that lost oligomerization and capsid-binding abilities to block HIV-1 in- ...and ...
10
An HIV 1 capsid binding protein TRIM11 accelerates viral uncoating
... HIV-1 capsid binding proteins have been identified [15, 16, 25, 27–30], most of which, like CSPF6, NUP153, NUP358, TNPO3 and CypA, were shown as dependency factors for HIV-1 replication [25, ...HIV-1 ...
14
Structural Basis for Human Norovirus Capsid Binding to Bile Acids
... norovirus capsid-protruding (P) domain using X-ray ...acid binding. Intriguingly, we discovered that binding of the bile acid was the critical step to stabilize several P domain loops that optimally ...
17
Papillomavirus capsid binding and uptake by cells from different tissues and species.
... PV binding onto the surfaces of different cell lines by using purified PV ...The binding of viral particles to cells does not neces- sarily mean that the particles can be taken up by the cells, since many ...
8
The Capsid-Binding Nucleolar Helicase DDX56 Is Important for Infectivity of West Nile Virus
... WNV capsid protein interacts with the host cell protein ...mature capsid (mCap) was cloned into pGBKT7, which was then cotransformed with empty vector (pGADT7) or pGADT7-DDX56 into the AH109 yeast ...WNV ...
10
Binding Site on the Transferrin Receptor for the Parvovirus Capsid and Effects of Altered Affinity on Cell Uptake and Infection
... virus binding and ...prevented binding to the capsids or reduced the affinity of receptor binding to various ...virus binding face of the apical domain also controlled capsid ...virus ...
10
Rubella Virus Capsid Protein Interacts with Poly(A)-Binding Protein and Inhibits Translation
... identified capsid-binding protein p32 are ...(C) Capsid together with histidine-tagged PABP or vector alone was expressed in HEK293T ...to capsid or PABP and then subjected to immunoblot (IB) ...
11
Residues of VP26 of Herpes Simplex Virus Type 1 That Are Required for Its Interaction with Capsids
... smallest capsid protein and decorates the outer surface of the capsid shell of herpes simplex ...of capsid protein interactions. An in vitro capsid binding assay and a green fluorescent ...
14
Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus
... the capsid-binding capabilities of the altered antibody variable do- mains we ...to binding conferred by specific residues Asp 155, Leu 204, and Thr 205, which were predicted from the previous ...
10
A Physical Link between the Pseudorabies Virus Capsid and the Nuclear Egress Complex
... the capsid protein ...a capsid-binding site for the pUL36 large tegument protein ...to capsid assemblies occurred only in the absence of pUL34, the use of the mutant library to identify the ...
10
Bamboo Mosaic Potexvirus Satellite RNA (satBaMV RNA)-Encoded P20 Protein Preferentially Binds to satBaMV RNA
... satBaMV contains 836 nucleotides [excluding the poly(A) tail] and encodes a 20-kDa nonstructural protein (P20) (34). In contrast to satellite-encoded proteins associated with nepovi- ruses, which are required for ...
8
Binding of Adenovirus Capsid to Dipalmitoyl Phosphatidylcholine Provides a Novel Pathway for Virus Entry
... Ad binding to phosphatidylcholine, we em- ployed a centrifugation assay originally developed to study protein-lipid interaction ...virus binding to liposomes ...
9
Mutations in the putative calcium-binding domain of polyomavirus VP1 affect capsid assembly.
... Immunofluorescence studies indicated that although viral protein synthesis occurred normally, infective viral progeny were not produced in cells transfected with polyomavirus genomes enc[r] ...
10
Deletion analysis of the capsid protein of Sindbis virus: identification of the RNA binding region.
... Our studies identified a 32-amino-acid region that is essential for the specificity in RNA binding, and they defined a 68-amino-acid minimal sequence which displays almost the complete s[r] ...
7
Adeno-Associated Virus Capsids Displaying Immunoglobulin-Binding Domains Permit Antibody-Mediated Vector Retargeting to Specific Cell Surface Receptors
... rAAV binding to specific cell surface receptors by simple coupling of different ligands to its ...(IgG) binding domain of protein A, Z34C, was inserted into the AAV2 capsid at amino acid position ...
8
Polycaryocyte formation mediated by Sindbis virus glycoproteins.
... These data suggest that glycosylation of virus proteins is essential for Sindbis virus-infected cells to express FFWI, but that the conversion of PE2 to E2 or the binding of capsid to th[r] ...
7
C-Terminal Arginine Cluster Is Essential for Receptor Binding of Norovirus Capsid Protein
... norovirus capsid protein plays an important role in the structure and function of the viral ...norovirus capsid proteins with trypsin resulted in removal of the S domain (9, 11, and this study) and the ...
10
Capsid Structure and Its Stability at the Late Stages of Bacteriophage SPP1 Assembly
... major capsid protein, but these additional amino acids are found in short insertions distributed between the land- mark secondary structure elements of the HK97 fold and at the protein termini rather than by the ...
10
Interaction Domains of the UL16 and UL21 Tegument Proteins of Herpes Simplex Virus
... The experiments described here have revealed new and fun- damental information regarding the interaction network in which the conserved UL16 tegument protein operates. In par- ticular, the previously unidentified 65-kDa ...
9
Venezuelan Equine Encephalitis Virus Capsid Protein Forms a Tetrameric Complex with CRM1 and Importin α/β That Obstructs Nuclear Pore Complex Function
... several binding sites that bind FG repeats, thereby melting the FG meshwork to ensure rapid cargo ...The capsid-specific tetrameric com- plex contains two karyopherins and about twice the FG-bind- ing sites ...
14