carboxy terminus
Characterization of Immunodominant Linear B-Cell Epitopes on the Carboxy Terminus of the Rinderpest Virus Nucleocapsid Protein
... the carboxy terminus and one antigenic site (aa 122 to 150) on the amino terminus of the MV N protein by using N deletion mutants and monoclonal antibod- ies, but they did not investigate the degrees ...
7
Monoclonal Antibody Routinely Used To Identify Avirulent Strains of Newcastle Disease Virus Binds to an Epitope at the Carboxy Terminus of the Hemagglutinin Neuraminidase Protein and Recognizes Individual Mesogenic and Velogenic Strains
... To further characterize antibody AVS-I and the epitope it recognizes, we have (i) determined its specificity for several additional strains of the virus, (ii) mapped its binding to HN in competition with our own ...
5
The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo
... variably carboxy- terminal truncated ...the carboxy terminus of TFPI was required for interacting with hepatoma cells, a mutant of TFPI lacking the third Kunitz-type domain and ...
10
Characterization and modification of the carboxy-terminal sequences of bluetongue virus type 10 NS1 protein in relation to tubule formation and location of an antigenic epitope in the vicinity of the carboxy terminus of the protein.
... the carboxy terminus of BTV-10 NS1 protein, using dele- tion, extension, and MAb ...the carboxy ter- minus of NS1, it was demonstrated that there is a linear epitope bound by MAb 10B1 located at the ...
11
Effects of Truncation of the Carboxy Terminus of Pseudorabies Virus Glycoprotein B on Infectivity
... PrV gB is a type I membrane glycoprotein of 913 amino acids (aa), including a 58-aa putative signal peptide; three C-terminally located hydrophobic domains, of which the last one probably represents the transmembrane ...
9
Antiserum specific for the carboxy terminus of the transforming protein of Rous sarcoma virus.
... To examine whether the anti-src-c sera would recognize cellular p6O'-$" uninfected chick cells were labeled with 2p, for 2 h, and then immunoprecipitates were prepared with two anti-src-[r] ...
8
Influenza virus hemagglutinin containing an altered hydrophobic carboxy terminus accumulates intracellularly.
... 1, AGMK cells infected with this mutant, dl-12 HA-SV40, synthesized a cellassociated HA of approximately 70,000 70K to 75K daltons, similar in size to the wild-type HA produced during in[r] ...
6
Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates
... mAb. In the initial screen, mAb C8 reacted with twosyn- thetic peptides which overlapped by 10 amino acids. The binding of C8 to peptide 440 ENQGGDKYPIHFNDE 454 resulted in a twice higher OD450 value when compared to C8 ...
9
Proteolytic Activity, the Carboxy Terminus of Gag, and the Primer Binding Site Are Not Required for Pol Incorporation into Foamy Virus Particles
... Proteolytic processing of Gag or Pol is not required for assembly of Pol into HFV particles. To better understand the role of the viral PR during assembly, we wanted to test whether the HFV PR active site mutant ...
7
Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen.
... Peptides used for immunization of mice and in characterization of antibodies Designation Amino acid sequences corresponding to Tthe of SV40 large carboxy-terminal region Lys-Thrz Hexamer[r] ...
9
Molecular basis of class III ligand recognition by PDZ3 in murine protein tyrosine phosphatase PTPN13
... free carboxy-terminus of the ligand cysteine residue located at position P0 (C0) is stabilised by hydrogen bonds to the backbone amide groups of L27 and G28, whereas the carbonyl group of F29 forms a ...
48
Structural elements that regulate pp59c-fyn catalytic activity, transforming potential, and ability to associate with polyomavirus middle-T antigen.
... Here we show that the carboxy terminus of pp59c-fyn is necessary for stable middle-T-antigen association, that pp59C-fyfis normally phosphorylated on both serine and tyrosine residues, a[r] ...
10
Characterization of LMP-1's association with TRAF1, TRAF2, and TRAF3.
... Amino acids 186 to 231 of LMP-1 are in its carboxy terminus and interact with the TRAF molecule in yeast (32). The last 53 amino acids (residues 334 to 386) of LMP-1 comprise a non- redundant domain that is ...
8
Concordant Modulation of Neutralization Resistance and High Infectivity of the Primary Human Immunodeficiency Virus Type 1 MN Strain and Definition of a Potential gp41 Binding Site in gp120
... the carboxy terminus of ...the carboxy-terminal ectodomain of gp41 associates with the trimeric structure formed by association of LZ structures, forming a six-helix, coiled-coil structure ...the ...
11
Molecular characterization of biologically diverse envelope variants of human immunodeficiency virus type 1 derived from an individual.
... This leads to a frameshift which results in the JS4 clones encoding 58 amino acids at the carboxy terminus of gp4l compared with 53 in pHXB2gpt, contributed from the gene encoding the ca[r] ...
5
Comparative analysis of core amino acid residues of H-2D(b)-restricted cytotoxic T-lymphocyte recognition epitopes in simian virus 40 T antigen.
... The minimal and optimal residues of T antigen recognized by the four CTL clones were determined by using synthetic peptides truncated at the amino or carboxy terminus and an H-2Db peptid[r] ...
8
Proteolytic Processing of a Serotype 8 Human Astrovirus ORF2 Polyprotein
... the carboxy-terminus of VP90 in Yuc8, to yield VP70, was not detected with the available sera, and further studies are required to determine the fate of this ...
7
Variability and Immunogenicity of Caprine Arthritis-Encephalitis Virus Surface Glycoprotein
... amino terminus of CAEV SU (amino acids 1 to 14) that differs by 50% in amino acid sequence from MVV SU, would be used as a group- specific ...the carboxy terminus of the protein (amino acids 512 to ...
8
Latency-Associated Nuclear Antigen (LANA) of Kaposi's Sarcoma-Associated Herpesvirus Interacts with Origin Recognition Complexes at the LANA Binding Sequence within the Terminal Repeats
... and carboxy termini of LANA for efficient ...the carboxy terminus of LANA is the primary binding site for the ORC complexes (see ...the carboxy terminus of LANA can support ...
14
Functional domains of the simian foamy virus type 1 transcriptional transactivator (Taf).
... The amino-terminal acidic region and a highly conserved sequence, among the taf genes of foamy viruses, located at the carboxy terminus were identified to be the activation domains of th[r] ...
7