casein kinase II
Activation of skeletal muscle casein kinase II by insulin is not diminished in subjects with insulin resistance
... To identify the putative postreceptor lesion responsible for insulin resistance in Pima Indians, we investigated the influence of insulin on the activity of casein kinase II CKII in skel[r] ...
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Phosphorylation of the Nuclear Form of Varicella-Zoster Virus Immediate-Early Protein 63 by Casein Kinase II at Serine 186
... for casein kinase II ...that casein kinase II phosphorylation of S186 occurs in the nucleus and possibly identifying an initial molecular event operative in VZV ...
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The Human Cytomegalovirus Virion Possesses an Activated Casein Kinase II That Allows for the Rapid Phosphorylation of the Inhibitor of NF-κB, IκBα
... ␣ kinase activity, allowing for direct phosphorylation of I B ␣ following virion entry into infected ...vitro kinase assays performed on purified HCMV virion extract identified bona fide I B ␣ ...
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Erythrocytic Casein Kinase II Regulates Cytoadherence of Plasmodium falciparum-infected Red Blood Cells
... Plasmodium falciparum malaria is a major human health scourge and a key cause of mortality. Its pathogenicity partly results from the phenomenon of “cytoadherence” mediated by the PfEMP1 (Plasmodium falciparum ...
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Casein kinase II and protein kinase C modulate hepatitis delta virus RNA replication but not empty viral particle assembly.
... and kinase inhibitor experiments, the phosphorylation levels of both HDAgs were diminished by the inhibitor of casein kinase II ...protein kinase C (PKC) inhibitor, suggesting different ...
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Rotavirus NSP1 Requires Casein Kinase II Mediated Phosphorylation for Hijacking of Cullin RING Ligases
... ABSTRACT The rotavirus nonstructural protein NSP1 repurposes cullin-RING E3 ubiqui- tin ligases (CRLs) to antagonize innate immune responses. By functioning as substrate adaptors of hijacked CRLs, NSP1 causes ...
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Regulation of the Drosophila melanogaster Protein, Enhancer of Rudimentary, by Casein Kinase II
... The Drosophila melanogaster gene enhancer of rudimentary , e(r), encodes a conserved protein, ER. Most ER homologs share two casein kinase II (CKII) target sites. In D. melanogaster , these sites are ...
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Phosphorylation of RIG-I by Casein Kinase II Inhibits Its Antiviral Response
... CK2 inhibits RIG-I signaling and suppresses RIG-I-medi- ated antiviral response. The protein kinase CK2 is a universal kinase that phosphorylates proteins at Ser/Thr. Bioinformation analysis reveals that ...
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Phosphorylation of varicella-zoster virus glycoprotein gpI by mammalian casein kinase II and casein kinase I.
... Lanes: 1, 4, and 7, immunoprecipitates added to protein kinase assays with no exogenous source of phosphotransferase activity; 2, 5, and 8, immunoprecipitates added to kinase assays with[r] ...
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The Phosphoprotein of Rabies Virus Is Phosphorylated by a Unique Cellular Protein Kinase and Specific Isomers of Protein Kinase C
... protein kinase(s) present in cell extract prepared from rat ...heparin-sensitive kinase was not the ubiquitous casein kinase II present in a variety of cell ...protein kinase C ...
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Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms.
... Tyrosine phosphorylation of gE in insect cells. Since the phosphorylation of the gE dimer was abolished when GTP was the phosphate source, the gE dimer was not primarily phos- phorylated by casein kinase ...
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Upregulation of the Chemokine (C-C Motif) Ligand 2 via a Severe Acute Respiratory Syndrome Coronavirus Spike-ACE2 Signaling Pathway
... tyrosine kinase (TK; amino acid residues 775 to 781) and casein kinase II (CK II; amino acid residues 787 to 790) in the cyto- plasmic domain are ...the casein kinase ...
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Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo.
... Differences in the oncogenic potential of the two large T antigens may also stem from the fact that although their Rb- binding domains are similar in structure, they are not identical. Within the primate polyomaviruses ...
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Differential Roles of the Glycogen-Binding Domains of β Subunits in Regulation of the Snf1 Kinase Complex
... protein kinase family, including the Snf1 kinase of Saccharomyces cerevisiae, are activated under conditions of nutrient ...protein kinase consisting of Snf1 ( ␣ ), Snf4 ( ␥ ), and one of three ...
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The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.
... protein kinase activity that coimmunopre- cipitates with Nef could phosphorylate MA on serine in vitro, by using the same major phosphoacceptors as observed in ...Nef-associated kinase, could use MA as an ...
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Minimal truncation of the c-myb gene product in rapid-onset B-cell lymphoma.
... In the present study we have attempted to elucidate the mechanism by which c-myb is oncogenically activated in EU- 8-induced B-cell lymphoma. We have characterized the tumor- specific myb mRNAs and proteins to determine ...
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Mechanism and evolution of cytosolic Hedgehog signal transduction
... Hh signal transduction in mammals utilizes the primary cilium, an evolutionarily conserved microtubule-based organelle analogous to the flagella found in single-celled eukaryotes, such as Chlamydomonas reinhardtii ...
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Casein Kinase 1α Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus
... type II IFN (IFN- ␥ ) receptor 1 (IFNGR1), as well as IFNAR1, via casein kinase 1 ␣ (CK1 ␣ ), resulting in the impairment of cellular responsiveness to both type I and II ...type II ...
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T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123.
... Traugh, and Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest DISCUSSION This study demonstrates that the ability of T-antigen kinase, an isoform of casein kinase I, to in[r] ...
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The emerging roles of phosphatases in Hedgehog pathway
... The existence of multiple PP2A targets in Hh pathway raised an important question of how PP2A selects its substrate. The character of PP2A functioning as a heterotrimeric complex might be the key to answer this question. ...
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