CCAAT enhancer-binding protein 1
Biological roles of CCAAT/Enhancer-binding protein delta during inflammation
... leaky and mild elevation of proinflammatory mediators. Selectively removing the suppressive nuclear receptors, including peroxisome proliferator-activated receptor α and retinoic acid receptor, on the promoter regions of ...
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Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts
... the protein causing the 23 kDa band in dif- ferentiating myoblasts, we performed an immunoprecipi- tation (IP) of whole cell extracts from C2C12 myoblasts differentiated for three days using the anti-C/EBPβ anti- ...
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CCAAT/enhancer binding protein β is required for satellite cell self-renewal
... Skeletal muscle has a remarkable capacity to regenerate after injury, which depends on the presence of muscle progenitor cells, called satellite cells (SC) [1, 2]. In adult muscle, satellite cells make up 2 – 7% ...
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CCAAT/enhancer binding protein β promotes receptor activator of nuclear factor kappa B ligand (RANKL) expression and osteoclast formation in the synovium in rheumatoid arthritis
... Recent studies indicated that C/EBPβ is involved in dif- ferentiation of osteoblasts and osteoclasts both physiolo- gically and pathologically. C/EBPβ activates osteocalcin gene transcription and promotes osteoblast ...
11
Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells
... regulatory protein (StAR) mRNA and protein levels. However, the protein levels of cytochrome P450scc and 3 beta-hydroxy-steroid dehydrogenase (3 beta-HSD) were unchanged after MBP ...factors ...
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CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
... file 1: Figure S1a). As shown in Fig. 2b–d and Additional file 1: Figures S1 and S2, the knockdown of CEBPD in U373MG and T98G cells significantly reduced the area and number of tumor spheroids after IL-1β ...
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Detrimental role for CCAAT/enhancer binding protein δ in blood borne brain infection
... inflammatory protein (MIP)-2 and MIP-1α response induced by IgG Immune complexes ...Chemoattractant Protein (MCP)-1 and endothelin-1 levels ...
6
The role of stromal cancer-associated fibroblasts in pancreatic cancer
... CHOP: CCAAT- enhancer-binding protein homologous protein; ECM: Extracellular matrix; EMT: Epithelial-mesenchymal transition; FAP: Fibroblast activation protein; FGF2: Fibroblast ...
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Endoplasmic reticulum stress and apoptosis
... associated protein 31; BiP – luminal binding protein; C/EBP – CCAAT/enhancer- binding proteins; eIF-2α – eukaryotic translation initiation factor; EOR – ER overloaded response; ...
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Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma
... The self-renewal capacity of CSCs is known to be one of the important features for the development of cancer. To explore the function of LAP1 on the self-renewal capac- ity of LCSCs, we first measured the effect of LAP1 ...
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British Journal of Medicine & Medical Research
... - CCAAT/enhancer-binding protein alpha; CTLA-4-cytotoxic T-lymphocyte-associated protein 4; DZ -dizygotic;FCRL3-Fc receptor-like protein 3; flCTLA-4- full-length CTLA-4; FOXP3- ...
31
Transcription factor CCAAT/enhancer binding protein alpha up-regulates microRNA let-7a-1 in lung cancer cells by direct binding
... vitro binding assay shows that all of the four C/EBP elements and C/EBP consen- sus sequence have binding capacity with nuclear protein extracted from H1299 cells with ectopic C/EBPα expres- ...these ...
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Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis
... the enhancer activity and the gene expression of the LD region (increasing the expression of TSFM/TSPAN31, reducing the expression of CYP27B1/METT21B/AVIL) in a allele-dependent and orientation-dependent way, by ...
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A Protein Encoded by the Bovine Herpesvirus 1 Latency-Related Gene Interacts with Specific Cellular Regulatory Proteins, Including CCAAT Enhancer Binding Protein Alpha
... Immunohistochemistry. wt-infected calves were euthanized, and their TG were fixed in neutral buffered formalin and then embedded in paraffin. Thin sections (4 to 5 um) were cut and mounted onto slides. Tissue sections ...
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Transcription factors: Are they a real target for future therapeutic strategies?
... factors CCAAT/enhancer binding protein (C/EBP), nuclear factor – AT (NF-AT) AP-1 controls the expression of the asthma associated cytokine IL-5 and can be activated also by rhinvirus ...
22
Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
... Activator protein 1; ARE: Androgen receptor element; C/EBP α : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate responsive element ...
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Docosahexaenoic acid increases accumulation of adipocyte triacylglycerol through up-regulation of lipogenic gene expression in pigs
... crude protein, ...− 1 copper in a pelleted feed consisting of 35% corn, 25% peas, 19% barley, 17% canola, and vitamin pre- mix including ...(Table 1) supplemented with 2% (as-fed basis) with beef ...
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Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients
... Although both AD-MSCs derived from healthy and SSc SVFs contained a subpopulation positive for CD271, a putative adipose stem cell marker [20], the SSc AD- MSCs lacked the ability to differentiate into functional ...
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C/EBP-alpha is an epithelial tumor suppressor gene, and mitogenic stimulation reciprocally regulates C/EBP-alpha and C/EBP-beta
... phosphorylation, protein induction, and DNA binding are blocked by the MEK inhibitor ...a protein loading ...containing 1 or 5μM of U0126 or DMSO ...except 1 and 5μM of the EGFR ...
147
TSG-6 secreted by human adipose tissue-derived mesenchymal stem cells ameliorates severe acute pancreatitis via ER stress downregulation in mice
... We separated PACs from C57BL/6 mice using collage- nase digestion, as previously described [21, 22]. Upon the complete dissociation of the pancreatic tissue, the enzym- atic reaction was stopped with the addition of cold ...
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