CCAAT/enhancer-binding protein β
CCAAT/Enhancer binding protein β induces motility and invasion of glioblastoma cells through transcriptional regulation of the calcium binding protein S100A4
... of CCAAT/Enhancer binding protein β (C/EBPβ) inhibits the growth of glioblastoma cells and diminishes their transformation capacity and ...calcium binding protein A4 ...
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Orosomucoid 2 inhibits tumor metastasis and is upregulated by CCAAT/enhancer binding protein β in hepatocellular carcinomas
... acute-phase protein, ORM2 likely plays important roles in anti-inflammation, immunomodulation and drug ...The CCAAT/enhancer binding protein β (C/EBPβ) upregulated ORM2 ...
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Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β
... Nuclear protein was extracted from mixed glial cultures after 2 h LPS or LPS+IFNg treat- ...and protein amount was determined by the Lowry assay (Total Pro- tein kit micro-Lowry, Sigma-Aldrich, ...
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Contaminating reactivity of a monoclonal CCAAT/Enhancer Binding Protein β antibody in differentiating myoblasts
... Objective: CCAAT/Enhancer Binding proteins (C/EBPs) are transcription factors involved in the regulation of a variety of cellular ...a protein other than ...
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CCAAT/enhancer binding protein β is required for satellite cell self-renewal
... C/EBP β leads to precocious differentiation at the expense of self-renewal in primary myoblast and myofiber ...C/EBP β -deficient satellite cells fail to self-renew resulting in a reduction of satellite ...
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CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
... IL-1 β induces the spheroid formation of glioma stem cells and is associated with the elevated CEBPD expression In GBM, inflammatory cytokines or growth factors, in- cluding IL-1β, IL-6, TGF-β, and EGF, are ...
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The CCAAT/enhancer binding protein (C/EBP) δ is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-β peptide
... DNA binding activity induced by IL-1b, rather than affecting C/EBPδ pro- tein ...both protein expression levels and binding activity to C/ EBP and B ...
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Myostatin gene promoter: structure, conservation and importance as a target for muscle modulation
... Activator protein 1; ARE: Androgen receptor element; C/EBP α : CCAAT/enhancer-binding protein- α ; ChoRE: Carbohydrate responsive element; ChREBP: Carbohydrate responsive element ...
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Biological roles of CCAAT/Enhancer-binding protein delta during inflammation
... CCAAT/enhancer-binding protein delta (CEBPD) is an intronless gene that encodes a 269-amino acid protein belonging to the CCAAT/enhancer-binding protein ...
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Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats
... CEBP β , CCAAT-enhancer binding proteins; CON, control; CPT-1A, Carnitine palmitoyltransferase 1A; CYP27A1, sterol 27-hydroxylase; FABP1, fatty acid binding proteins; FAS, fatty acid ...
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Genomic effects of the vitamin D receptor: Potentially the link between vitamin D, immune cells, and multiple sclerosis
... the enhancer activity and the gene expression of the LD region (increasing the expression of TSFM/TSPAN31, reducing the expression of CYP27B1/METT21B/AVIL) in a allele-dependent and orientation-dependent way, by ...
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C/EBP-alpha is an epithelial tumor suppressor gene, and mitogenic stimulation reciprocally regulates C/EBP-alpha and C/EBP-beta
... DNA binding and activity of C/EBPβ in proliferating keratinocytes after stimulation with EGF, suggest a possible role for C/EBPβ in the transcription of genes involved in entry into S phase (chapter ...
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Transcription factors: Are they a real target for future therapeutic strategies?
... proximal binding of essential transcription factors to the TATA-box and their interaction with the RNA polymerase II and co-activators has been studied for several transcription factors their function as a ...
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The role of stromal cancer-associated fibroblasts in pancreatic cancer
... activation protein (FAP), and fibroblast- specific protein-1 (FSP-1) [28, ...actin-binding protein highly expressed in cancers, actually precedes αSMA expression in cells undergo- ing ...
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Docosahexaenoic acid increases accumulation of adipocyte triacylglycerol through up-regulation of lipogenic gene expression in pigs
... The mechanisms by which dietary n-3 PUFA suppress hepatic lipogenesis and TAG secretion and induce fatty acid oxidation are well-known [57–59]. These mecha- nisms have also been confirmed in our previous pig studies [17, ...
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The Many Faces of C/EBPδ and their Relevance for Inflammation and Cancer
... Monocyte and dendritic cell infiltrations are seen in the hypoxic regions of solid tumors, particularly associated with necrotic tissue, and HIF-1α is required for the recruitment of myeloid cells [161]. Does C/EBPδ ...
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Next-Generation Sequence Analysis of the Genome of RFHVMn, the Macaque Homolog of Kaposi's Sarcoma (KS)-Associated Herpesvirus, from a KS-Like Tumor of a Pig-Tailed Macaque
... (B) Protein maximum-like- lihood analysis with a molecular clock of a 1,313-aa concatenated sequence from the DNA polymerase and glycoprotein B of the Old World primate rhadinoviruses, lymphocryptoviruses, and ...
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Oligonucleotides targeting coagulation factor mRNAs: use in thrombosis and hemophilia research and therapy
... endothelial protein C receptor, and protease-activated receptors) are predominantly expressed in the ...the protein of interest in both experimental ani- mals (during preclinical studies) and humans (actual ...
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CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis
... Array-based genomic hybridization is essential in searching for the key chromosomal regions harboring critical genes. In UC, chromosomal gains in 1q, 3p, 6p, 8q, 10p, 17q, and 20q are frequently identified [2, 3]. The ...
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British Journal of Medicine & Medical Research
... by binding fragments of processed antigens in the form of peptides and presenting them on the surface of an antigen-presenting cell (APC) to the T-cell receptor ...
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