CD45 expression, alternative splicing, and TCR signalling
Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells
... influence splicing of MALT1 by either promoting inclusion (for example, hnRNP R, hnRNP LL and SRSF3) or skipping (for example, hnRNP H1, hnRNP A1, U2AF1 and hnRNP U) of ...exon7 splicing is controlled by a ...
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The control of alternative splicing of the leucocyte common antigen (CD45)
... Therefore the possible involvem ent of a m utated transacting factor was addressed in subsequent studies. The entire chromosome content in somatic cell hybrids can be determined with a modified FISH technique using whole ...
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HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing
... 6. CD45 RNA-dependent interaction of hnRNP L and LL in ...of CD45 minigenes and experimental protocol. (B) Interaction depends on CD45 RNA expression: HeLa cells were transfected with either ...
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SmN: Expression and potential role in alternative mRNA splicing
... of alternative splicing pathways result from differential promoter usage or differential ...the splicing machinery or other Sm associated ...undergo alternative splicing from the same ...
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Control of human papillomavirus gene expression by alternative splicing
... isoform expression was demonstrated to be regulated by EGF ( Rosenberger et ...intron splicing and E6*I ...control splicing, Brm and Sam68 were ...regulate splicing by con- trolling the rate ...
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The expression and alternative splicing of alpha neurexins during Xenopus development
... from alternative splicing, resulting in a large number of protein isoforms, the significance of which is currently ...neurexin expression and alternative splicing during development of ...
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Differential gene expression and alternative splicing in insect immune specificity
... A large number of genes are downregulated after infec- tion. Naively, we might expect genes fighting infections to be upregulated after infection. We have two possi- ble explanations. The more exciting of the two is that ...
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Alternative initiation and splicing in dicer gene expression in human breast cells
... noticed that it is infested with many upstream open reading frames (uORF) and out of frame AUG codons [16]. To evalu- ate whether the 5'-untranslated region of the dicer transcript is in part responsible for the ...
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A functional analysis of G23A polymorphism and the alternative splicing in the expression of the XPA gene
... the alternative mRNA on RNA isolated from normal human ...the alternative junction of exon 1- exon 2, amplifying only the alternative transcript) and the second, nested PCR was performed using the ...
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Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma
... transgene expression, as monitored by flow cytometry analysis of EGFP- expressing ...the expression of the EGFP gene as well as the puromycin resistance gene and the shRNA included in the pGIPZ vector, was ...
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Truncated human endothelin receptor A produced by alternative splicing and its expression in melanoma
... Figure 5 Northem blot analysis of ETA mRNA transcript for melanoma cell lines and normal heart sample.. Full-length human ETA cDNA was used as a.[r] ...
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Alternative Splicing and Expression Profile Analysis of Expressed Sequence Tags in Domestic Pig
... humans. Alternative splicing is a cellular mechanism in eukaryotes that greatly in- creases the diversity of gene ...products. Expression sequence tags (ESTs) have been widely used for gene ...
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Cold-dependent expression and alternative splicing of Arabidopsis long non-coding RNAs
... gene expression when responding to changing environmental ...gene expression, extensive alternative splicing (AS) of pre-mRNAs and changes in expression of long non-coding RNAs ...
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A study of alternative splicing in the pig
... candidate alternative isoforms were identified in the EST data with high ...tissue-specific alternative splice events was generated from the list of ...with expression patterns matching those of the ...
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Alternative splicing in plant defence
... gene expression in a size dependant manner, the longer the intron the greater the gene expression ...increased expression of this transcript in infected ...gene expression of the JAZ3 in ...
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Pharmacology of modulators of alternative splicing
... D. Pain Mammalian pain pathways are highly complex. The peripheral signals indicative of tissue damage or in- fection are detected by peripheral neurons, and the input from these is processed at multiple levels of the ...
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Alternative splicing in lung cancer
... of Alternative Splicing in Lung Cancer Therapy and Detection Drugs that modulate alternative splicing have been proposed as potential therapeutic tools for lung ...of splicing factors ...
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Alternative splicing in prostate cancer.
... suggest alternative splicing may contribute to treatment resistance to ...increased expression of an alternatively spliced BRCA1 isoform, ...mRNA splicing mechanisms to remove deleterious ...
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HIV 1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages
... Tat expression during long-term infection in these cells is not due to changes in the rate of decay of its mes- sage, which appears to be relatively constant and similar to that in infected ...in expression ...
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Regulation of early and late HIV-1 gene expression by alternative pre-mrna splicing
... a splicing regulatory factor of the SR protein family, U2AF 65 was found to be dispensable for splicing of the chimeric PIPEG pre-mRNA substrate in vitro ...for splicing in almost all cases, U2AF 65 ...
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