CD4+ T cells
Memory CD4+ T cells do not induce graft versus host disease
... Donor T cells that accompany stem cell grafts cause GVHD by attacking recipient tissues; therefore, all patients receive GVHD prophylaxis by depletion of T cells from the allograft or through ...
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CD4+ T Cells Develop Antiretroviral Cytotoxic Activity in the Absence of Regulatory T Cells and CD8+ T Cells
... ⫹ T cells on CD4 ⫹ T cell cytotoxicity is also not understood, but similar findings were made in CD8-depleted, simian immunodeficiency virus (SIV)- infected macaques, where GzmB-expressing ...
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The Role of CD4 T Cells in the Pathogenesis of Murine AIDS
... Th2 CD4 T cells were adoptively transferred into ...both CD4 Th1 and Th2 cells were clearly able to mediate MAIDS after infection with ...unfractionated CD4 T ...
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HIV restriction in quiescent CD4+T cells
... quiescent T cells raised the possibility that quiescent T cells can be a reservoir that could support a spreading ...resting cells of HIV infected patients but this was attributed to ...
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Heterogeneity of human effector CD4+T cells
... dendritic cells, acted as powerful inducers of human Th1 polarization [10-12], I hypo- thesized that the type of innate immunity response was the main conditioning mechanism for the type of subsequent adaptive ...
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HIV integrase and the swan song of the CD4 T cells?
... having CD4 cell counts up to 600 per mm 3 ...in T/B lymphoblastoid cell line CEMX174, but also in primary CD4 T cells activated with ...of CD4+ T ...of T ...
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Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques
... prolonged T cell receptor (TCR) stimulation were shown to progressively redirect CD4 ⫹ T cell development away from a Th1 response during acute infection and toward a Tfh-dominated response during ...
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Modelling the dynamics of CD4+ T cells with and without delay
... the CD4+ T lymphocytes, which are the most abun- dant white blood cells of the immune system (referred to as helper T-cells or CD4+ T ...Helper T-cells play ...
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ts1, a temperature-sensitive mutant of Moloney murine leukemia virus TB, can infect both CD4+ and CD8+ T cells but requires CD4+ T cells in order to cause paralysis and immunodeficiency.
... In some experiments, a specific subset of T cells was depleted in vivo by intraperitoneal administration of 0.5 mg of anti-CD4 for CD4+ T cells or anti-CD8 for CD8+ T cells antibodies on[r] ...
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CD70–CD27 ligation between neural stem cells and CD4+ T cells induces Fas–FasL-mediated T-cell death
... on CD4 + T cells, we assessed expres- sion of several co-stimulatory molecules on ...and T cells by ...human CD4 + and CD8 + T cells were found to express mRNA for ...
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Hypomethylation and overexpression of ITGAL (CD11a) in CD4+ T cells in systemic sclerosis
... normal CD4 + T cells [21]. CD11a overexpression in CD4 + T cells can induce major- histocompatibility-complex-specific T cell autoreactivity in vitro and autoimmunity in ...
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Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia
... of CD4+ T lymphocytes, accompanied by opportunistic infections characteristic of the acquired immune deficiency syndrome, ahs been reported in the absence of any known ...idiopathic CD4+ T ...
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Clonal analysis of CD4+ T cells
... both CD4^ and CD8^ populations than other ...CD8^ cells. Expansions were also seen in CD4^ cells, but there were fewer detected and they were smaller than those seen in CD8^ ...f CD4^ ...
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The Role of SLP-76 in the Homeostasis of CD4+ T Cells
... Soluble IL-7 cytokine brings together the IL-7R α (CD127) chain and the common- γ chain to form a signaling complex (reviewed in (Kittipatarin & Khaled 2007)). Bringing these two chains into close proximity allows ...
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Recent developments in the effort to cure HIV infection: going beyond N = 1
... mary T cell models of latency (reviewed in refs. 69, 70). T cell acti- vation was used to reverse latency in the original studies defining the latent reservoir (4, 5), but this activation is associated with ...
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Cognate CD4 T-Cell Licensing of Dendritic Cells Heralds Anti-Cytomegalovirus CD8 T-Cell Immunity after Human Allogeneic Umbilical Cord Blood Transplantation
... CMV-specific CD4 ⴙ T-helper cells precede primary CMV- specific CTL expansion after ...that CD4 ⫹ T cells, through DC licensing, may support CMV-specific CTL re- sponses, as was ...
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Cellular interactions between lymphocytes and retinal endothelial cells
... by CD4^ T cells since brain EC can become the target for antigen-specific, MHC class II restricted cell-mediated cytotoxic damage (Risau et ...to T cells, their ability to present the ...
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CTL ACTION DURING HIV 1 IS DETERMINED VIA INTERACTIONS WITH MULTIPLE CELL TYPES
... Resting CD4 T cells in blood cells/mm.. Log Activated T cells in LT.[r] ...
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DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis
... in CD4, CD8, and CD14 cells from PBC patients and controls, coupled with gene expression profile from the same ...CXCR3-expressing cells in peripheral blood is known to be higher in PBC patients, and ...
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Anti-p19 Antibody Treatment Exacerbates Lyme Arthritis and Enhances Borreliacidal Activity
... lymphocytes, CD4 ⫹ T cells, and CD4 ⫹ CD25 ⫹ T cells in the lymph nodes (popliteal and inguinal) draining the site of the arthritic ...these cells was increased in ...
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