Cell death receptor apoptosis
Complexity of apoptotic pathways in leukemia treated with chemotherapy or cellular immunotherapy
... the death receptor pathway in chemotherapy-induced apoptosis, the involvement of this pathway in the elimination of leukemic cells by cytotoxic T lymphocytes (CTLs) was also largely ...to cell ...
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Picornaviruses and Apoptosis: Subversion of Cell Death
... Toll-like receptor 3 (TLR-3) recognizing cytoplasmic double-stranded RNA (dsRNA), a picornaviral replication intermediate (23, 27) ...Toll–IL-1 receptor (TIR) domain ...induces apoptosis (29), ...
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Oncolytic Vesicular Stomatitis Virus Induces Apoptosis in U87 Glioblastoma Cells by a Type II Death Receptor Mechanism and Induces Cell Death and Tumor Clearance In Vivo
... mitochondrial apoptosis pathways, often overexpressing anti- apoptotic proteins such as Bcl-X L (25, ...of apoptosis usually leads to inhibition of tumor regression in response to ...prevent, cell ...
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Death receptors couple to both cell proliferation and apoptosis
... cytokine receptor γ ...T cell death, known as activation-induced cell death (AICD), is activated by repeated stimulation by the antigen ...
6
TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment
... its death receptors DR4 and DR5 induces a conformational change of their death domains which, along with their oli- gomerization, is the functional activation of the ...with Death Do- main (FADD) on ...
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Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
... death receptor pathway ...and cell apoptosis ...induces apoptosis in many carcinoma cells via intrinsic mitochon- dria pathway ...
8
Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy
... Stem cell secretion of therapeutic molecules can initially be divided into two categories depending on whether they directly target tumor cells or support immune ...related apoptosis inducing ligand ...
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Original Article Identification of genes associated with apoptosis-sensitive acute lymphoblastic leukemia responsive to ionising radiation by bioinformatics analyses
... for apoptosis sensitive acute lympho- blastic leukemia (ALL) by identifying differential genes using bioinformatics ...between apoptosis-sensitive B-precursor ALL tumors responsive to ionising radiation ...
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A Brief Review on Apoptosis
... of apoptosis are highly complex and sophisticated, involving an energy-dependent cascade of molecular ...or death receptor pathway and the intrinsic or mitochondrial ...the cell. The ...
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K+ATP CHANNELS MODULATE HAEMODYNAMICS, BIOCHEMICAL AND HEMATOLOGICAL AFTER PRETREATMENT WITH THE K (ATP) OPENER PINACIDIL AND PHOSPHOLIPASE C INHIBITOR ON ETOMIDATE IN THE MICE
... induce cell death in different cell lines, being reported mainly apoptosis and necrosis as the principal pathways of cell death mediated by blockage of K + channels or the Na, ...
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Enhancement of death receptor mediated apoptosis in multiple myeloma cells
... myeloma cell lines as well as the patient specimens of multiple myeloma are characterized by neoplastic plasma cells that expressed the Syndecan-1 (CD138) cell surface antigen (Kuehl and ...human ...
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Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
... transformed cell lines by a number of soluble fac- tors (34–38), and represents a major activation pathway in- volved in modulation of cell growth, differentiation and apop- tosis in different cellular ...
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The enhanced expression of death receptor 5 (DR5) mediated by HBV X protein through NF kappaB pathway is associated with cell apoptosis induced by (TNF α related apoptosis inducing ligand) TRAIL in hepatoma cells
... enhance cell proliferation, migration, invasion and metastasis [5, ...mediating cell apoptosis by the death receptor pathway or mitochondrial dependent pathway ...
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Interaction Between Mitochondria and Caspases: Apoptotic and Non-Apoptotic Roles
... induced cell death without inducing an inflammatory ...of cell death immunologically ...and apoptosis in an entirely Bax/Bak- and death receptor/FADD–independent ...
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Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts
... TRICK2A: death receptor 5 or DR5 (also Apo2; TRAIL-R2; TRICK2; or KILLER); IAP3: inhibitor of apoptosis protein 3; HSIAH2: inhibitor of apoptosis protein 2; IRRP + DAP1: ...
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Original Article Dihydroartemisinin and cisplatinum synergistically induced apoptosis in human lung adenocarcinoma H1299 cells
... control. Cell inhibition and apoptosis were evaluated by MTT assays and flow ...The apoptosis associated proteins were assessed by Western blotting and ...H1299 cell apoptosis compared ...
12
Reconstitution of the T-cell compartment post-allogeneic haematopoietic stem cell transplantation
... A great deal o f work has been focused on understanding the regulation o f the peripheral T -cell pool, both under normal circumstances and under conditions o f severe lymphopenia. Several studies using mouse ...
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Morphological Identification of Cell Death in Dorsal Root Ganglion Neurons Following Peripheral Nerve injury and repair in adult rat
... developmental cell death period, peripheral neurons are absolutely dependent on trophic factors produced by their targets, and those developing neurons that fail to compete successfully for sufficient ...
8
Prognostic value of aberrant promoter hypermethylation of tumor-related genes in early-stage head and neck cancer
... HNSCC cell proliferation via ERK1/2-mediated effects on cell cycle control proteins, such as p27, p57, and cyclin D1 ...non-small cell lung cancer prediction ...
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Apoptosis in Murine Norovirus-Infected RAW264.7 Cells Is Associated with Downregulation of Survivin
... apoptotic death of infected cells, we studied morpho- logical and biochemical changes induced in ...infected cell led to displacement of the nucleus ...by apoptosis is nuclear chromatin condensation ...
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