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cell epitope

Computational Methods in Linear B cell Epitope Prediction

Computational Methods in Linear B cell Epitope Prediction

... Immune systems protect the body from foreign molecules known as antigens. It has great pattern recognition capability that may be used to distinguish between foreign cells entering the body (non- self or antigen) and the ...

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Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope.

Characterization of T-cell response to woodchuck hepatitis virus core protein and protection of woodchucks from infection by immunization with peptides containing a T-cell epitope.

... T-cell epitope mapping with overlapping peptides, covering the entire WHcAg, revealed T-cell responses of acutely WHV-infected woodchucks to peptide 1–20 , peptide 100–119 , ...

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Identification of a T-helper cell epitope on the rotavirus VP6 protein.

Identification of a T-helper cell epitope on the rotavirus VP6 protein.

... designed such that they overlapped by 22 amino acids to en- sure that no Th-cell epitope would be missed. These two fusion proteins also allowed us to map the antigenic regions of VP6. For the assay, spleen ...

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Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1.

Identification of a T-cell epitope adjacent to neutralization antigenic site 1 of poliovirus type 1.

... Immunization of BALB/c H-2d mice with the uncoupled p86-115 peptide, which represents VP1 amino acids 86 to 115 and contains both the T-cell epitope and the C3 neutralization epitope, in[r] ...

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Inclusion of a specific T cell epitope increases the protection conferred against foot and mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site

Inclusion of a specific T cell epitope increases the protection conferred against foot and mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site

... B-cell epitope (site A) peptide or with TB, a peptide where the B-cell epitope was in tandem with the T-cell epitope [3A ...T-cell epitope used is capable to induce ...

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Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

... protein epitope was identified by subjecting a series of partially overlapping synthesized peptides to enzyme-linked immunosorbent assay (ELISA) ...linear epitope that could be recognized by mAb ...linear ...

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Original Article Analysis of T-cell epitopes of Der f3 in Dermatophagoides farina

Original Article Analysis of T-cell epitopes of Der f3 in Dermatophagoides farina

... T-cell epitope of Der f3. We initially developed the T-cell fraction from BALB/c mice sensitized with recombinant Der f3 to determine the T-cell epitopes in the murine models, and performed T ...

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IN SILICO HOMOLOGY STRUCTURE, B CELL AND T CELL EPITOPES PREDICTION OF SERINE/THREONINE PROTEIN KINASE A AGAINST TUBERCULOSIS

IN SILICO HOMOLOGY STRUCTURE, B CELL AND T CELL EPITOPES PREDICTION OF SERINE/THREONINE PROTEIN KINASE A AGAINST TUBERCULOSIS

... in cell division, cell differentiation and cell ...B-cell epitope and T-cell mapping that highlights the immunogenic part of a ...

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Enhancement of the antibody response to flavivirus B-cell epitopes by using homologous or heterologous T-cell epitopes.

Enhancement of the antibody response to flavivirus B-cell epitopes by using homologous or heterologous T-cell epitopes.

... DISCUSSION This is the first report of a biologically active flavivirus Th-cell epitope capable of providing help for a homologous flavivirus B-cell antibody response to another peptide [r] ...

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Evaluation of recombinant multi epitope proteins for diagnosis of goat schistosomiasis by enzyme linked immunosorbent assay

Evaluation of recombinant multi epitope proteins for diagnosis of goat schistosomiasis by enzyme linked immunosorbent assay

... multi- epitope proteins were constructed and their potential as diagnostic antigens for goat schistosomiasis was evalu- ated in this ...of epitope prediction, several online software analytical methods were ...

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In silico-based vaccine design against Ebola virus glycoprotein

In silico-based vaccine design against Ebola virus glycoprotein

... an epitope-based peptide vaccine against EBOV, using a combination of B-cell and T-cell epitope predictions, followed by molecular docking and molecular dynamics simulation ...

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Advancement and applications of peptide phage display technology in biomedical science

Advancement and applications of peptide phage display technology in biomedical science

... B-cell epitope is cross-reactive to astrocyte elevated gene-1 (AEG-1), a human protein on human endothelial cells that may cause some dengue patients to suffer from hemorrhagic fever (DHF) or dengue shock ...

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Immunoinformatics Based Vaccine Design for Zea M 1 Pollen Allergen

Immunoinformatics Based Vaccine Design for Zea M 1 Pollen Allergen

... and remained stable in the range of 1.0 Å to 1.2 Å. As seen in Figure 4a, highest B factor (atomic fluctuation) is observed for SER residue at the position of 342 in HLA-epitope complex, while lowest B factor ...

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Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice  Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes

Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes

... B Cell Epitope Recognition in Arthritis 1683 grecan, when depleted of KS, induces a similar arthritis and ...arthritogenic epitope(s) responsible for this arthritis is located in the G1 do- main of ...

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Chronic development of collagen induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

Chronic development of collagen induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

... B cell epitope specificity in chronic CIA models; that is, with an active joint inflammation later than 6 weeks after the ...between epitope specificities and the different phases of the disease and ...

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The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design

The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design

... by sequence variation within or flanking targeted epitopes (1, 6, 11, 14, 15, 18, 20, 23–25). The accumulation of escape variants within epitopes presented by the HLA class I alleles expressed in an infected individual ...

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Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus.

Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus.

... Humoral response to either the B-cell epitope peptide B, the T-helper cell epitope peptide T or the combination peptide T-B, using Quil A as an adjuvant Peptide used for immunization' B [r] ...

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Index Catalog // Carolina Digital Repository

Index Catalog // Carolina Digital Repository

... are cell cycle regulated, yet this mode of regulation is not universal as SLBP protein is expressed uniformly through the cell cycle in Drosophila cells (Lanzotti et ...are cell cycle ...

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Vertical T cell immunodominance and epitope entropy determine HIV 1 escape

Vertical T cell immunodominance and epitope entropy determine HIV 1 escape

... T cell response that targeted the classical Gag 240–249 epitope (TW10), which has a low entropy (lowest tertile in our data set, see Supplemental Table ...this epitope occurred within days (usual ...

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Different Methods of Identifying New Antigenic Epitopes of Human Papillomavirus Type 16 E6 and E7 Proteins

Different Methods of Identifying New Antigenic Epitopes of Human Papillomavirus Type 16 E6 and E7 Proteins

... that cell-mediated im- mune responses are critical for HPV ...frequent cell-mediated immune responses to E6 and E7 in HPV 16-positive women who had not devel- oped SIL than in HPV 16-positive women with SIL ...

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