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Cell junctions

The Herpes Simplex Virus gE-gI Complex Facilitates Cell-to-Cell Spread and Binds to Components of Cell Junctions

The Herpes Simplex Virus gE-gI Complex Facilitates Cell-to-Cell Spread and Binds to Components of Cell Junctions

... extensive cell contacts or junctions, and HSV and other herpesviruses spread across these cell ...from cell to cell through a space that is isolated by tight junctions, HSV races ...

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The Extracellular Domain of Herpes Simplex Virus gE Is Sufficient for Accumulation at Cell Junctions but Not for Cell-to-Cell Spread

The Extracellular Domain of Herpes Simplex Virus gE Is Sufficient for Accumulation at Cell Junctions but Not for Cell-to-Cell Spread

... mediate cell-to- cell spread by binding to receptors concentrated at cell junc- tions ...in cell-to-cell spread and not in entry of extracellular virions (10) and (ii) gE/gI accumulates ...

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Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)

Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)

... adherens junctions), and with the extracellular matrix (integrin-based focal ...these cell junctions evolved is central to understanding early tissue evolution in ...the cell–substrate ...

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ADAM9 Is Present At Endothelial Cell - Cell Junctions And Regulates Monocyte – Endothelial Transmigration

ADAM9 Is Present At Endothelial Cell - Cell Junctions And Regulates Monocyte – Endothelial Transmigration

... to cell-cell junctions with VE-Cadherin in confluent endothelial ...to cell- cell junctions suggesting the ADAM9 ectodomain may ...on cell-cell ...endothelial ...

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HDAC6 inhibition prevents TNF-α-induced caspase 3 activation in lung endothelial cell and maintains cell-cell junctions

HDAC6 inhibition prevents TNF-α-induced caspase 3 activation in lung endothelial cell and maintains cell-cell junctions

... endothelial cell apoptosis and endothelial barrier disruption [7, 9, ...endothelial cell dysfunction such as hyper-permeability ...of cell junction complex [2–4], contributing to TNF-α-induced ...

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Cell matrix interactions and cell cell junctions during epithelial histo morphogenesis in the developing mouse incisor

Cell matrix interactions and cell cell junctions during epithelial histo morphogenesis in the developing mouse incisor

... mesenchyme posterior to the labial part of the cervical loop (lab CL) of the lower incisor at ED14 by light (A,B) and trans- mission electron micros- copy (C-G). Sagittal histo- logical section of the inci- sor showing ...

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Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions

Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions

... Taken together, our data support a somewhat different role for Rasip1 during lymphatic vessel development than the one which has been reported during blood vessel formation (Xu et al., 2011). We predict that Rasip1 plays ...

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A “Tric” to tighten cell cell junctions in the cochlea for hearing

A “Tric” to tighten cell cell junctions in the cochlea for hearing

... Tricellulin is a tricellular tight junction–associated membrane protein that controls movement of solutes at these specialized cell intersections. Muta- tions in the gene encoding tricellulin, TRIC, lead to ...

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Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles

Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles

... endothelial cell-cell junctions was confirmed in BMEC cultures (Additional file 1: Figure S1) and spinal cord cryosections from naïve Tie-2-eGFP-CLN-5 mice ...

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Intercellular Diffusion of a Fluorescent Sucrose Analog via the Septal Junctions in a Filamentous Cyanobacterium

Intercellular Diffusion of a Fluorescent Sucrose Analog via the Septal Junctions in a Filamentous Cyanobacterium

... ABSTRACT Many filamentous cyanobacteria produce specialized nitrogen-fixing cells called heterocysts, which are located at semiregular intervals along the filament with about 10 to 20 photosynthetic vegetative cells in ...

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Willing to be involved in cancer

Willing to be involved in cancer

... Cell junctions are protein dense regions that play an extremely important role in epithelial tissues, such as the maintenance of apicobasal polarity, intercellular communication, promotion of adhesive ...

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Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular node function and connexin 45 localization in the murine heart

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular node function and connexin 45 localization in the murine heart

... the cell-cell junctions of the AV node but preservation of connex- in 40 and 43 in contracting myocardial cells and connexin ...AV-node cell-cell junction and of β-catenin and ZO-1 at ...

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A correlative and quantitative imaging approach enabling characterization of primary cell-cell communication: Case of human CD4+ T cell-macrophage immunological synapses

A correlative and quantitative imaging approach enabling characterization of primary cell-cell communication: Case of human CD4+ T cell-macrophage immunological synapses

... Contact-based cell communication is an essential mode of crosstalk in the functioning of mammalian organs, tissues, nervous and immune ...functional cell connections is there- fore important to tackle ...

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Herpes Simplex Virus gE/gI Expressed in Epithelial Cells Interferes with Cell-to-Cell Spread

Herpes Simplex Virus gE/gI Expressed in Epithelial Cells Interferes with Cell-to-Cell Spread

... from cell to cell in both these ...infections, cell-to-cell spread appears to be especially important in order for these viruses to outrun the immune system, especially after reactivation in ...

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The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction

The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction

... these three proteins, RhoB has distinct biochemical and biological properties compared with RhoA and RhoC. RhoA and RhoC are modified at their C-terminus by the addition of a geranylgeranyl group, whereas RhoB can also ...

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... Inter-Sertoli cell junctions were completely lacking or partly deleted (Figure ...including cell shrinkage, membrane blebbing, and excessive chromatin condensation (Figure ...

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Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

... planar cell polarity signaling pathway (Kelly and Chen, 2007; Montcouquiol and Kelley, 2003; Montcouquiol et ...which cell intercalations occur and cell-cell junctions appear or ...

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Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium

Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium

... specific cell columns initiate alignment events, strongly suggests the involvement of positional signals that are limited to, or emanate from, denticle field ...four-cell junctions in the tracheal ...

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2 O sulfotransferase regulates Wnt signaling, cell adhesion and cell cycle during zebrafish epiboly

2 O sulfotransferase regulates Wnt signaling, cell adhesion and cell cycle during zebrafish epiboly

... in cell culture and invertebrates, little is known about their functions or abilities to modulate specific cell signaling pathways in vertebrate ...deep cell adhesion and fail to initiate epiboly, ...

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Effect of amplitude and duration of impulsive pressure on endothelial permeability in in vitro fluid percussion trauma

Effect of amplitude and duration of impulsive pressure on endothelial permeability in in vitro fluid percussion trauma

... endothelial cell-cell adhesions mainly consist of adherens junctions (AJs) and tight junctions ...intercellular junctions to the cell membrane, as shown in Figure 7B, and block ...

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