cell proliferation and motility
Original Article miR-25 is up-regulated in non-small cell lung cancer and promotes cell proliferation and motility by targeting FBXW7
... non-small cell lung cancer (NSCLC) is still ...and cell lines. Inhibition of miR-25 remarkably suppressed cell proliferation, migration and invasion in NSCLC cells, whereas enforced expression ...
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Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway
... CCA cell proliferation and motility is not ...CCA cell proliferation and ...of proliferation and colony forma- tion and decreased levels of phosphatidyl inositol-3-kinase (PI3K) ...
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FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7
... Next we examined whether depletion of the high level of endogenous FAM83D proteins in BT549 cells (Fig. 1B) inhibited the cell proliferation and motility phenotypes. FAM83D was depleted using both ...
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Targeting the Sheddase Activity of ADAM17 by an Anti-ADAM17 Antibody D1(A12) Inhibits Head and Neck Squamous Cell Carcinoma Cell Proliferation and Motility via Blockage of Bradykinin Induced HERs Transactivation
... including proliferation and migration through the shedding of a diverse array of substrates such as epidermal growth factor receptor (EGFR) ...squamous cell carcinoma ...suppresses proliferation and ...
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The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer
... The section containing NFKB1 promoter region with poly- morphisms rs4648068 was obtained by PCR using primers pGL-promoterFor1 and pGL-promoterRev (Table 1). DNA templates were extracted from peripheral blood samples of ...
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<p>RCC2 Interacts with Small GTPase RalA and Regulates Cell Proliferation and Motility in Gastric Cancer</p>
... SGC-7901 and MGC-803 cells were transfected with two siRNAs speci fi cally targeting RCC2 and an overexpression vector. siRNA transfection ef fi ciency was measured by fl uorescence microscopy using FAM-siRNA (data not ...
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Cancer related ectopic expression of the bone related transcription factor RUNX2 in non osseous metastatic tumor cells is linked to cell proliferation and motility
... To assess whether expression of RUNX2 in MDA- MB-231 cells is facilitated by protein stabilization, we reactivated proliferation in serum deprived MDA-MB- 231 cells in the absence or presence of the protein ...
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<p>Tizanidine (Hydrochloride) Inhibits A549 Lung Cancer Cell Proliferation and Motility Through Regulating Nischarin</p>
... squamous cell carcinoma ...the proliferation of A549 cells. (F) Cell invasion and invasion were detected using transwell ...(G) Cell apoptosis was analyzed using flow ...squamous cell ...
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Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS
... fluorochrome labeled monoclonal antibodies: anti-Foxp3 (FJK-16s), anti-IL-17 (eBio17B7) and anti-IFNγ (XMG1.2). All antibodies were purchased from BD Pharmigen or eBioscience. For cell number quantification, 10 4 ...
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Knockdown of Golgi phosphoprotein 2 inhibits hepatocellular carcinoma cell proliferation and motility
... anchorage-independent cell colony formation assays and a xenograft tumor model to show that GP73-specific siRNAs inhibit HCC proliferation in HepG2, SMMC-7721, and Huh7 cell lines and in ...but ...
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TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p
... promote cell migration and invasion through IL-11/STAT3 signaling pathway ...and cell culture system, the authors failed to analyze the expres- sion patter of TMED3 on clinical tissue ...
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Original Article MiR-125a suppresses ovarian cancer proliferation and motility by targeting HDAC4
... non-small cell lung cancer (NSCLC) ...with cell proliferation and tumor progression ...the proliferation, migration and inva- sion activities of gastric cancer cells via target- ing E2F3 ...in ...
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The control of cell motility and differentiation by Ras pathways
... for proliferation emanating from the studies w ith dom inant proteins were not confirmed in the Ras-deficient ...general cell proliferation ...
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JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer
... affect cell proliferation (Figure 2A and ...cancer cell lines (see Additional file 5, Figure ...increased proliferation (see Additional file 6, Figure S4), and this was confirmed in individual ...
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Syntaphilin controls a mitochondrial rheostat for proliferation motility decisions in cancer
... of proliferation-motility decisions in tumors ...tumor cell proliferation versus cell invasion and dissemination, in ...between cell proliferation and cell ...
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Cell proliferation in human melanoma
... 1 1000-2000 melanoma cells were evaluated for labeling index, mitotic index, grain count, and per cent labeled mitoses.. Determination of DNA specific activity.[r] ...
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S100P enhances the motility and invasion of human trophoblast cell lines
... chemotaxis-directed motility (A,B) or directional migration after ...the Cell IQ automated image capture system, (Chip-Man Technologies) in which pre-selected fields were imaged using phase contrast ...
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Modelling cell motility and chemotaxis with evolving surface finite elements
... the cell successfully responds to the changing signal exhibiting a clear directional preference for movement in the direction of higher chemoattractant ...the cell successfully responds to the change in ...
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The role of the tissue microenvironment in the regulation of cancer cell motility and invasion
... How quickly cancer cells are able to migrate through connective tissue in vivo is still debated. In vitro, migra- tion speeds of up to 25 microns per minute through col- lagen networks have been reported [45]. It is ...
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Chicken primordial germ cell motility in response to stem cell factor sensing
... stromal cell derived factor-1 (SDF-1), stem cell factor (SCF), e-cadherin, laminin and fibronectin, have been reported to function as either chemokinetic, chemotactic or adhesion molecules (reviewed in ...
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