cell subsets/phenotype
Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis
... Altered monocyte function, including diminished HLA-DR expression and impaired proinflammatory cytokine response, was previously reported in patients with sepsis, severe trauma and major surgery. Such monocytic ...
12
The hepatitis B virus core and e antigens elicit different Th cell subsets: antigen structure can affect Th cell phenotype.
... Recombinant proteins and synthetic peptides. The HBV core (HBc) gene encodes two polypeptides. Initiation of translation at the first start codon (AUG) results in a 25-kDa precore protein that is secreted as HBeAg after ...
10
Cytokine Production by Vγ+-T-Cell Subsets Is an Important Factor Determining CD4+-Th-Cell Phenotype and Susceptibility of BALB/c Mice to Coxsackievirus B3-Induced Myocarditis
... Two coxsackievirus B3 (CVB3) variants (H3 and H310A1) differ by a single amino acid mutation in the VP2 capsid protein. H3 induces severe myocarditis in BALB/c mice, but H310A1 is amyocarditic. Infection with H3, but not ...
10
HTLV 1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus infected individuals
... T-cell subsets, we used flow cytometry to analyze the T-cell phenotype and HTLV-1 infection in peripheral mononuclear cells (PBMCs) of four groups of subjects, including 23 HTLV-1-infected ...
12
CD28-, CD45RAnull/dim and natural killer-like CD8+ T cells are increased in peripheral blood of women with low-grade cervical lesions
... T-cell subsets can be phenotypic- ally classified by CCR7 expression in combination with that of CD45RA ...the phenotype CD28–, CD16+/56+, and effector memory subsets in the peripheral blood ...
10
Preferential replication of HIV 1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro
... T cell stimuli, the maturational state of CD4 lymphocytes also influences both the degree of cell proliferation and the capacity to sup- port productive HIV ...CD45RA phenotype proliferate to higher ...
13
Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis
... immature phenotype comparable with PB ...mature phenotype (increased expression of CD80, CD83 and CD86) compared with PB ...DC subsets matured following toll-like receptor ...
13
STAT5 levels in regulatory T-cell subsets
... T regs (0.039, p = 0.0768) subsets, supporting a higher proliferative capacity of this T reg subset over the two others. These results are consistent with the differences observed in unstimualted T regs and ...
12
Characterization of the murine T cell subsets defined by CD45RA isoforms
... activated phenotype (Ledbetter et ...CD4+CD45R- subsets could proliferate well to a variety of mitogens, only the CD4+CD45R- subset could provide help for antibody production and proliferate in response to ...
312
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
... glycolytic phenotype in ...T cell subsets in vivo. The metabolic phenotype of 2D2 TCR transgenic T cells spe- cific for myelin oligodendrocyte glycoprotein (MOG) was, there- fore, observed ...
15
Disseminated cytomegalovirus disease after bendamustine: a case report and analysis of circulating B and T cell subsets
... T-cell phenotype with outgrowth of terminally-differentiated and effector memory at the dis- advantage of naïve phenotypes, suggest functional exhaus- tion, possibly reflecting chronic viral antigenic ...
5
Alteration of B-Cell Subsets Enhances Neuroinvasion in Mouse Scrapie Infection
... The conclusion reached in this study that closeness of the FDC network and the peripheral nervous system in CD19 ⫺/⫺ mice may allow a more efficient migration of prions between the two sites is supported by a recent ...
5
Differential transcriptome and development of human peripheral plasma cell subsets
... exit cell cycle, gain expression of BLIMP-1, and upregulate receptors for homing to the BM ...every cell in pops 2 to 5, consistent with the loss of CD20 that begins as early as 7 days after vaccination in ...
21
Glycolysis determines dichotomous regulation of T cell subsets in hypoxia
... use glucose metabolism that is similar to that of activated T N (17). The high glycolytic activity of T EXP is critical for their functionality in hypoxia, given that partial inhibition of glycolysis in T EXP using low ...
12
Epitope specific airway resident CD4+ T cell dynamics during experimental human RSV infection
... all study participants is reassuring because all current RSV vac- cine candidates include F protein as the main antigen (31). How- ever, with a combination of inference from each subject’s HLA type, in silico prediction ...
17
Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab
... DC subsets are therefore decreased in the blood of RA patients with active disease, but only mDCs cor- relate inversely with disease activity – suggesting that this mDC decrease could reflect a migration to ...
10
Immunological aspects of polymyalgia rheumatica and giant cell arteritis
... synovial fluids, while Bhardwaj et al (1988) could detect no ILIB in either. Even in those studies showing raised immunoreactive ILIB in RA synovial fluid, the actual levels found have varied considerably. Westacott et ...
183
Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets
... the cell surface molecules CCR5 and CD40 can upregulate A3G expression in CD4 ⫹ T cells and DCs ...and cell type expression profiles of human APOBEC3 genes, the variation in APOBEC3 mRNA expression levels ...
12
Differential Response of Respiratory Dendritic Cell Subsets to Influenza Virus Infection
... RDC subsets after influenza virus ...DC subsets differ in their profiles of cytokine/chemokine production in response to in- flammatory stimuli, such as virus or bacterial infections (11, 19, ...RDC ...
12
B cell profiling in malaria reveals expansion and remodeling of CD11c+ B cell subsets
... B cell numbers, were expanded in both malaria-infect- ed groups compared with healthy controls at the time of acute infection (primary infected: ...B cell phenotypic analysis by mass ...B cell subset ...
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