Cellular stress
Roles of Long non coding RNAs in Cellular Stress Response
... The cellular system is constantly subjected to stress in response to a variety of conditions such as a transient exposure to hot or cold temperatures, heavy metals, exogenous chemicals, oxidative ...
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The Role of Tra1 in Cellular Stress Responses in Yeast: Implications for Human Diseases
... of cellular stress responses, especially the HSR, in cancer ...the cellular malignant phenotypes by increasing resistance to apoptosis (Mendillo et ...
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p53 Reaction to Cellular Stress Maximizes Apoptosis in Glioblastoma
... the stress selectivity of ...of cellular stress, doxorubicin and bortezomib caused DNA double-strand breaks and shutdown of protein turnover, which were more threatening to cell survival than halt in ...
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Evolution of the cellular stress proteome: from monophyletic origin to ubiquitous function
... The cellular stress response is a mechanism of extraordinary significance for many areas of biology and ...of stress have been studied ...on cellular responses to perturbations in only a ...
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Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses
... cell stress responses such as the formation of stress granules and phosphorylation of the translation initiation factor eIF2 ␣ ( ␣ subunit of eukaryotic initiation factor ...of stress granule ...
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Role of RGS2 in Cellular Stress
... of stress response targets involved in metabolism, nutrient uptake and amino acid biosynthesis, control of redox status, apoptosis and autophagy 222,240,241 ...
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A Systems Biological Perspective of Cellular Stress Directed Programmed Cell Death
... of cellular stress (Figure 2(a), lower ...to stress autophagy inducer quickly gets activated through down-regulation of crosstalk element, meanwhile apoptosis inducer remains fully ...when ...
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Sumo and the cellular stress response
... During recent years it has become clear that Sumo has important functions in normal cell homeostasis, in large part through regulation of transcription (reviewed in Chymkowitch et al., submitted). However, Sumo is also ...
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Mitochondrial proteomics on human fibroblasts for identification of metabolic imbalance and cellular stress
... to stress response, one to mitochondrial transla- tion and one contains miscellaneous ...oxidative stress; the translation (TRANS) category contains proteins of the mitochondrial transla- tion machinery and ...
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Reovirus Induces and Benefits from an Integrated Cellular Stress Response
... in cellular gene expression vary dramatically depending on the infecting ...identifying cellular pathways that regulate translation in reovirus-infected cells, we used Affymetrix U74Av2 murine- specific ...
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Cellular stress response mechanisms of Rhizoma coptidis: a systematic review
... Rhizoma coptidis plays a therapeutic role in insulin resistance partly by regulating the TLR4/JNK/NF-κB pathways and Akt/AMPK/GLP-1/ERS pathways. In the insulin resistance models, Rhizoma coptidis acts on the ...
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Characterization of cellular stress systems using biological mass spectrometry
... Effect of domain specific constructs on progression through cell cycle (A) Cell cycle profile of transfected cells presented as representative histogram data plots. 28 2 (ACT3), or Flag[r] ...
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PubMedCentral-PMC4808044.pdf
... inhibit cellular proliferation, suppress HMGCR enzymatic activity, cause mitochondrial DNA damage, cell cycle arrest, induce apoptosis and cellular stress, and block cellular adhesion and ...
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A novel Fizzy/Cdc20 dependent mechanism suppresses necrosis in neural stem cells
... Fig. 6. Overexpression of p53 induces the necrosis of neuroblasts by attenuating the Fzy-dependent survival mechanism. (A-D) Neuroblasts experiencing catastrophic cellular stress expressed the p53 reporter ...
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Cellular eIF2B subunit localisation: implications for the integrated stress response and its control by small molecule drugs
... integrated stress response (ISR), which results in the down-regulation of global protein synthe- sis and the concomitant expression of stress-specific factors such as ...to cellular stress, ...
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Stress, Drugs, and Evolution: the Role of Cellular Signaling in Fungal Drug Resistance
... that cellular stress re- sponses may play a role in triazole resistance in ...reduced cellular accumulation of the antifungals, suggesting a possible role for multidrug transport- ers ...
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Early cellular changes are indicators of pre-bleaching thermal stress in the coral host
... and cellular stress responses of the host, which have the potential to impact the holobiont physiology, need to be determined especially if we are to understand the role of environ- mental stressors in ...
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Cytoprotective Effect of Hydroalcoholic Extract of Pinus eldarica Bark against H2O2-Induced Oxidative Stress in Human Endothelial Cells
... The effects of P. eldarica extract on intra- and extra- cellular hydroperoxides levels were determined based on the ferrous ion oxidation by xylenol orange reagent (FOX1) [22] . The FOX-1 reagent containing ...
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Series Introduction: The expanding network of redox signaling: new observations, complexities, and perspectives
... as cellular NADPH oxidases, nitric oxide synthases, or mitochondria, diffuse widely, and then have their sig- naling integrated by proteins such as thioredoxins and other ...
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Effect of Vitamin E and Sodium Selenite on the Expression of Baxand Bcl2Genes and Renal Histopathology in the Electromagnetic Field-Exposed Mice
... Penetration of magnetic and electrical fields into the cell membranes increases the risk of DNA damage and tissue damage by prolonging free radical stability, altering membrane potential, reducing the activity of ...
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