chromatin remodelling
EARLY IN SHORT DAYS 1 (ESD1) encodes ACTIN RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis
... in chromatin-mediated transcriptional ...via chromatin remodelling, as it is a component of the human SWI/SNF and yeast INO80 complexes that are involved in chromatin remodelling, ...
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p63 and Brg1 control developmentally regulated higher order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells
... higher-order chromatin folding and transcriptional regulation of the EDC locus in keratinocytes (Fessing et ...in chromatin organisation and remodelling, including Brg1 (Fessing et ...higher-order ...
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The ATP dependent chromatin remodelling enzyme Uls1 prevents Topoisomerase II poisoning
... (ATP)-dependent chromatin remodelling (Snf2) enzyme, can alter Top2 chromatin binding and prevent Top2 poisoning in ...function. Remodelling Top2 bind- ing is thus an important new means by ...
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Putative molecular mechanism underlying sperm chromatin remodelling is regulated by reproductive hormones
... Histones, that have not been degraded, persist in the nu- clei of the elongated spermatids and lead to the formation of sperm with abnormal nuclear shapes [50]. When mature caput sperm of CPA-treated rats were treated ...
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BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling complex—a tumour suppressor or tumour-promoting factor?
... BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes including development. Mutations in SMARCA2, a ...
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The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer
... affecting chromatin formation and interfering with the initiation and elongation of DNA replication ...the chromatin in self-protection, and triggers apoptosis via distinct pathways in platinum sensitive ...
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Seed dormancy cycling in Arabidopsis : chromatin remodelling and regulation of DOG1 in response to seasonal environmental signals
... DOG1 chromatin in seeds in the SSB and on soil disturbance and exposure to light this accumu- lation is ...that chromatin remodelling contributes to the reg- ulation of DOG1 expression with DOG1 ...
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Role of the SWI/SNF Chromatin Remodelling Complex in the Axon Development of the Drosophila Mushroom Body
... Neuronal remodelling occurs throughout development in order to establish the mature pattern of dendrites and axons in the adult ...Non-Fermentable) chromatin remodelling complex in the axon ...
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The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22
... In conclusion, we demonstrate that SMARCB1/INI1 deficiency, alone or in combination with TP53 muta- tions, influences the CRC aggressive behavior, regardless of the MMR status. Surprisingly, even SMARCB1/INI1 diffuse ...
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Chromatin remodelling during plant pathogen interactions
... in chromatin remodelling such as histone acetyltransferases (HATs), HDACs, histone methyltransferases (HMTs) and chromatin remodelling complexes ...
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Farnung, Lucas (2017): Nucleosome-Chd1 structure and implications for chromatin remodelling. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... The nucleosome was formed with Widom 601 nucleosomal DNA and 63 bp of extranucleo- somal DNA. This is the first high-resolution structure of a full-length chromatin remodeller bound to the nucleosome. The ...
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Nieberler, Markus (2012): Function of the CHD4/Mi-2ß chromatin remodelling ATPase during neural development of Xenopus laevis. Dissertation, LMU München: Medizinische Fakultät
... A further step in cellular (re-)programming is provided by the recent results of Marius Wernig’s group, which efficiently converted mouse embryonic and postnatal fibroblasts into functional neurons in vitro, referred to ...
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Expression of DjXnp, a novel member of the SNF2 like ATP dependent chromatin remodelling genes, in intact and regenerating planarians
... ABSTRACT SWI/SNF-related complexes include proteins implicated in the regulation of gene expression by chromatin remodelling. We have identified in planarians, invertebrates well-known for their ...
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Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo
... The similar histone modifications and replication tim- ing profiles between ES and TS cells is consistent with mounting evidence indicating that only relatively few genes are uniquely restricted to the placenta, the vast ...
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ROLE OF RNAi IN HETEROCHROMATIN FORMATION AND CHROMATIN REMODELLING
... Our lab members have been pioneers in this area of research, contributing several milestones in unraveling the nuances of RNAi. As early as 1997, when there was no speculation of co-suppression in animals, Pal-Bhadra et ...
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Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
... of chromatin fibre formation (Debelouchina et ...DNA. Chromatin folding to form higher order structures is likely to be favoured by fully wrapped nucleosomes, and so an increase in the propor- tion of ...
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A new paradigm for developmental biology
... in chromatin remodelling enzymes and binding effector proteins, such as SET, tudor domains and chromodomains, appear to interact with RNA (Bernstein and Allis, 2005; Jeffery and Nakielny, 2004; ...
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Prothymosin α, a protein implicated in the proliferation and survival of lymphocytes
... to chromatin activity through its interaction with core histones and proteins involved in chromatin remodelling, whereas, processes related to the phosphorylation, the proteolytic processing to ...
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Hartlepp, Klaus F. (2006): Characterisation of CHRAC14 and CHRAC16, the two Histone Fold Subunits of the Chromatin Accessibility Complex. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... active Chromatin Accessibility Complex, but so far, co-expression and co-purification of all four subunits together do not give satisfying results (see ...ATP-dependent chromatin remodelling ...
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Defining the molecular events required for GM CSF gene activation in T cells
... 1.4 RESEARCH PROJECT AIMS The aim of this study was to identify the role of signals and factors activated following T cell stimulation in regulating chromatin remodelling and transcripti[r] ...
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