Chromatin structure and remodelling
Chromatin remodelling in Sacchromyces cerevisiae by RSC
... of chromatin structure and function DNA is a long, charged molecule thus it has to be packaged within cells by proteins in order to compact it into the relatively small space of the ...a structure ...
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ROLE OF RNAi IN HETEROCHROMATIN FORMATION AND CHROMATIN REMODELLING
... of chromatin structure (Van Holde K ...2002) Chromatin associated proteins such as HP1, Pc, Swi6 identify these specific histone tail modifications and initiate the formation and maintenance of ...
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Chd5 orchestrates chromatin remodelling during sperm development
... Extensive chromatin remodelling occurs during spermiogen- esis, which results in the majority of nucleosomal histones being replaced by sperm-specific basic proteins, initially transition proteins and ...
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The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer
... affecting chromatin formation and interfering with the initiation and elongation of DNA replication ...the chromatin in self-protection, and triggers apoptosis via distinct pathways in platinum sensitive ...
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The ATP dependent chromatin remodelling enzyme Uls1 prevents Topoisomerase II poisoning
... into chromatin; a complex arrangement of DNA and associated binding pro- ...within chromatin, a universal problem facing eukaryotes is how to access their genetic ...matin structure through the ...
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Chromatin structure and DNA damage repair
... repair, chromatin remodelling is most likely a ...on chromatin remodelling with respect to the cellular response to DNA damage, with emphasis on the response to lesions resolved by nucleotide ...
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Seed dormancy cycling in Arabidopsis : chromatin remodelling and regulation of DOG1 in response to seasonal environmental signals
... of chromatin remodelling acting as a control- ling gateway to the induction of changes in dormancy sta- ...in chromatin structure associated with histone ...
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Regulation of DNA replication by chromatin structure in mammalian cells
... Discussion 101 Another possible way in which ORC could take advantage of the increased remodelling occurring at promoter sites would be through the process of nucleosome eviction. It has been demonstrated that ...
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Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome
... The movie frames were subjected to frame wise motion correction using MotionCor2 (Zheng et al., 2017). CTF correction was then performed on the motion corrected summed image using GCTF (Zhang, 2016). Subsequent image ...
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Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids
... symmetric substitution rates influences the evolution of isochore structure. Mol. Biol. Evol. 25, 362–374 (2008). Acknowledgements We are indebted to the patients donating their tumour specimens as part of the ...
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Farnung, Lucas (2017): Nucleosome-Chd1 structure and implications for chromatin remodelling. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... I determined the structure of full-length S. cerevisiae Chd1 bound to a nucleosome core particle at a nominal resolution of 4.8 ˚ A. Chd1 binds the NCP on one side of the nucleosome and peels two full helical ...
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Role of the SWI/SNF Chromatin Remodelling Complex in the Axon Development of the Drosophila Mushroom Body
... ATP-dependent chromatin remodelling complex that has been implicated in the aetiology of intellectual disability ...brain structure required for learning and ...
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Tup1 Ssn6 and Swi Snf remodelling activities influence long range chromatin organization upstream of the yeast SUC2 gene
... static structure, chromatin is now accepted to have a dynamic organization from the nucleosomal level up to higher order structures ...and remodelling of nucleosome arrays has revealed previously ...
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Chromatin remodelling during plant pathogen interactions
... the chromatin binding kinetics of HAG1-GFP change after flg22 ...with chromatin following flg22 perception in order to contribute towards in- creased histone ...
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Keywords: globin genes, locus control regions, chromatin remodelling, enhancers
... As described above, the regions of the globin locus responsible for chromatin opening have not been identified and presumably lie outside the confines of the LCR as classically defined. Such a function is likely ...
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ISWI Remodelling of Physiological Chromatin Fibres Acetylated at Lysine 16 of Histone H4
... ATP-dependent chromatin remodelling factors that catalyse the sliding of nucleosomes along DNA and thereby endow chromatin with structural ...reconstituted chromatin fibres with physiological ...
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Putative molecular mechanism underlying sperm chromatin remodelling is regulated by reproductive hormones
... nicked chromatin in the pool of mature caput sperm of FD-treated rats, indicated the failure of a FSH-mediated chromatin repair mechanism, operative in the elongating spermatids of stages XI to XII tubules ...
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piRNA clusters and open chromatin structure
... generally has negative effects on the host genome. To counteract this threat, host cells have evolved genetic and epigenetic mechanisms that keep TEs silenced. One such mechanism involves the Piwi-piRNA complex, which ...
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Chromatin, DNA structure and alternative splicing
... [60] . In this study, they observed that nucleosomes impose a bar- rier for RNAPII progression, increasing pause density and duration and decreasing RNAPII apparent velocity. According to their model, when RNAPII finds a ...
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A Model for the Structure of Chromatin in Mammalian Sperm
... By using available data on the composition of the mouse (70) and bull (5) sperm nucleus, amino acid sequence data on fish (1-3, 15, 16, 41) and bull (24) protamine, and a great deal of t[r] ...
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