chronic cerebral hypoperfusion
Neuroprotection targeting protein misfolding on chronic cerebral hypoperfusion in the context of metabolic syndrome
... and chronic cerebral hypoperfusion ...syndrome, chronic cerebral hypoperfusion, neuroprotection, protein misfolding, endoplasmic reticulum stress, chaperones, neurodegenerative ...
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The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion
... for cerebral WM disease 42, 43 and relates to WM damage and cognitive dysfunction 44-46 apparent in ...that chronic cerebral hypoperfusion in mice or rats 47 leads to reduced ...between ...
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Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion
... long-term chronic cerebral hypoperfusion induced by BCAS produced similar glial damage, glial activation and proliferation as evident in ...after chronic cerebral ...
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Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment
... See http://ivyspring.com/terms for full terms and conditions. Received: 2021.10.21; Accepted: 2022.01.03; Published: 2022.01.16 Abstract The prevalence of cerebrovascular disease increases with age, placing the elderly ...
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Chronic cerebral hypoperfusion induces post-stroke dementia following acute ischemic stroke in rats
... stroke. Chronic cerebral hypoperfusion (CCH) can induce vascular cognitive impairment and potentiate amyloid ...middle cerebral artery occlusion (MCAO) surgery in rats mimicking acute ...
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Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
... Decreased cerebral blood supply, which is associated with dementia, results in chronic cerebral hypoperfusion (CCH), a physiopathological mechanism of neural dysfunction in Alzheimer’s ...
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Salvia miltiorrhiza extract protects white matter and the hippocampus from damage induced by chronic cerebral hypoperfusion in rats
... by chronic cerebral hypoperfusion can damage not only white matter but also gray matter including the hippocampus [48, ...to chronic BCCAo in the hippocampus and white ...with chronic ...
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Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation
... Mild chronic cerebral hypoperfu- sion affected glucose metabolism, most probably by impairing glucose biodistribution leading to GSK3β ac- ...mild chronic cerebral hypoperfusion on NVU ...
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URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion
... that chronic cerebral hypoperfusion (CCH), a state of chronic cere- bral blood flow reduction, is associated with several cerebrovascular and neurodegenerative disorders in- cluding ...
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Fructus mume alleviates chronic cerebral hypoperfusion induced white matter and hippocampal damage via inhibition of inflammation and downregulation of TLR4 and p38 MAPK signaling
... on chronic cerebral hypoperfusion-induced brain dysfunction through inhibit- ing MBP degradation, activation of microglia and astro- cytes, increased proinflammatory mediator expression, and ...
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Prophylactic combined supplementation of choline and docosahexaenoic acid attenuates vascular cognitive impairment and preserves hippocampal cell viability in rat model of chronic cerebral hypoperfusion ischemic brain injury
... BCCAO rats have either failed to learn or failed to retrieve memory of the previous unpleasant experience of foot shock delivered in the dark compartment and demonstrates poor retention memory as evidenced by short ...
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TREM-2-p38 MAPK signaling regulates neuroinflammation during chronic cerebral hypoperfusion combined with diabetes mellitus
... Eight weeks after BCCAO or sham surgery, rats under- went MWM test to assess spatial learning and memory. There was no significant difference in escape latency on the first day among the four groups. Either DM or CCH ...
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Original Article Icariside II affects hippocampal neuron axon regeneration and improves learning and memory in a chronic cerebral hypoperfusion rat model
... The cerebral blood flow is sus- tainably reduced for 4 to 12 weeks, which reproduces similar pathological physiological changes that occur during human CCH ...
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<p>A Novel Octapeptide Derived From G Protein-Coupled Receptor 124 Improves Cognitive Function Via Pro-Angiogenesis In A Rat Model Of Chronic Cerebral Hypoperfusion-Induced Vascular Dementia</p>
... acute cerebral hypoperfusion, which is a sudden disruption of the blood supply to distinct brain regions leading to ischemic stroke followed by the BBB ...focal cerebral ischemic damage by reducing ...
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Middle cerebral artery alterations in a rat chronic hypoperfusion model
... and remodeling was paralleled by an increase in wall stress. Structural alterations of the MCA were accompanied by a decrease in collagen I/III protein expression by a mechanism that may involve increased degradation via ...
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Expression Analysis of MiR 124 in Experimental Cerebral Hypoperfusion
... DOI: 10.4236/jbm.2018.65002 10 Journal of Biosciences and Medicines ological processes including differentiation, morphogenesis, proliferation and apoptosis. However, recent researches have also found that this ...
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Transient cerebral ischemia Association of apoptosis induction with hypoperfusion
... of cerebral blood flow and reversibil- ity of the ischemic ...of cerebral perfusion alone did not lead to a signifi- cant induction of apoptosis in cat brain during the duration of reperfusion that we ...of ...
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Cerebral Hemodynamics in Chronic Disorders of Cerebral Circulation
... the cerebral bed are shown. 87 patients with chronic cerebral ischemia (CCI) on the background of hypertension (GB) were examined, of the 36 women and 51 men aged from 46 to 72 ...internal ...
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Improved detection of cerebral hypoperfusion with internal carotid balloon test occlusion and 99mTc HMPAO cerebral perfusion SPECT imaging
... A new method that employs a cerebral perfusion imaging agent, 99 mTc-HMPAO, is described for identifying those patients who clinically pass an internal carotid arte[r] ...
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Cerebral palsy as a chronic disease of the
... dyskinetic cerebral palsy depends on the period, etiology, and spot of the brain ...dyskinetic cerebral palsy retrospectively using videotape recordings made at 5 to 8 months of ...
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