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CIN I

CIN III lesions and regression: retrospective analysis of 635 cases

CIN III lesions and regression: retrospective analysis of 635 cases

... Results Among 1495 patients screened for this study, 635 patients fulfilled the inclusion criteria and had both a cervical biopsy showing a CIN III lesion p16 positive and a consecutive [r] ...

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The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity

The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity

... induce CIN which, in turn, leads to stress adap- tation by karyotype diversity ...through CIN [77]. A recent in silico simulation of CIN cell populations performed by Laughney and colleagues provides ...

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GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny

GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny

... the brain can- not accumulate somatic chromosome mutations through mitotic divisions, it is difficult to solve this paradox. Here, we suggest aneuploidy remaining in the human brain after developmental cell clearance to ...

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Vitamin C may exert variable effects on viability and proliferation of HeLa cells exhibiting high and low chromosomal instability

Vitamin C may exert variable effects on viability and proliferation of HeLa cells exhibiting high and low chromosomal instability

... Cancers are heterogeneous in nature. Some degree of nu- merical and structural defect in chromosomes, termed as CIN, is present in most tumors. The current literature has emphasized the presence of populations of  ...

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Cervical precancerous changes and selected cervical microbial infections, Kiambu County, Kenya, 2014: a cross sectional study

Cervical precancerous changes and selected cervical microbial infections, Kiambu County, Kenya, 2014: a cross sectional study

... (CIN) I, II, III, cervical cancer and microbial infection (Actinomyces, Trichomonas vaginalis and Yeast cells) diagnosis was based on Pap smear screening test and High Vaginal Swab wet preparation ...

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Obesity is not associated with contrast nephropathy

Obesity is not associated with contrast nephropathy

... The focus of this study was to determine whether obesity, when stratified by BMI, is a risk factor for CIN in a large and hemodynamically stable population of hospitalized United States veterans. For this reason, ...

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The Effect of Corticotropin (ACTH) on Glomerular Permeability to Albumin in Children with the Nephrotic Syndrome

The Effect of Corticotropin (ACTH) on Glomerular Permeability to Albumin in Children with the Nephrotic Syndrome

... If it is accepted that the clearance of inulin CIN is equivalent to GFR in children with the nephrotic syndrome 3, it follows that the renal clearance of albumin CALB divided by CIN, i.e[r] ...

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Comparison between the Hybrid Capture II Test and a PCR Based Human Papillomavirus Detection Method for Diagnosis and Posttreatment Follow Up of Cervical Intraepithelial Neoplasia

Comparison between the Hybrid Capture II Test and a PCR Based Human Papillomavirus Detection Method for Diagnosis and Posttreatment Follow Up of Cervical Intraepithelial Neoplasia

... CIN II ⫹ by PCR and 18.9% for CIN III and 24.1% for CIN II ⫹ by HCII. It should be noted that the specificity refers to the specificity in a clinical secondary screening setting where all women have ...

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A Comparative Study of Low Power Area Efficient Carry Select Adder

A Comparative Study of Low Power Area Efficient Carry Select Adder

... A full adder adds binary numbers and accounts for values carried in as well as out. A one-bit full adder adds three one-bit numbers, often written as A, B, and Cin; Aand Bare the operands, and Cin is a bit ...

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Chitosan Interferon-γ Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses

Chitosan Interferon-γ Nanogene Therapy for Lung Disease: Modulation of T-Cell and Dendritic Cell Immune Responses

... without CIN treatment was isolated and assayed with the mouse TranSignal Interferon-inducible Gene Array Kit, as described in Materials and ...by CIN treatment is shown. B, Ribonuclease protection assay for ...

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A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.

A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.

... that CIN, assessed by the two independently derived CIN expression signatures, is significantly associated with increased tumour size, ER negative or HER2 positive disease, higher tumour grade and younger ...

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Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix

Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix

... Although CIN is known to be a true neoplasm and frequently progresses to CSCC (2, 6), genetic alterations of CIN are largely ...analyze CIN and CSCC genomes in this ...both CIN and ...between ...

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Preventive Effect of Pretreatment with Intravenous Nicorandil on Contrast Induced Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Angiography (PRINCIPLE Study)

Preventive Effect of Pretreatment with Intravenous Nicorandil on Contrast Induced Nephropathy in Patients with Renal Dysfunction Undergoing Coronary Angiography (PRINCIPLE Study)

... Based on these observations, we hypothesized that nicor- andil may protect the kidney from ischemic injury associat- ed with the use of contrast media by inhibiting the accumu- lation of ROS, suppressing synthesis of ...

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Mechanism Research on PM2 5 Charging, Precipitation in High Electrostatic Field

Mechanism Research on PM2 5 Charging, Precipitation in High Electrostatic Field

... Thus, the collection efficiency could be derived as: Cin − Cout η = × 100% 1 Cin where η is the collection efficiency, Cin is the initial number concentration of fine particles, and Cout[r] ...

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Combination Antifungal Therapy for Cryptococcal Meningitis

Combination Antifungal Therapy for Cryptococcal Meningitis

... ter i cin B resulted in faster CSF yeast clearance than did am pho ter i cin B monotherapy or am pho ter i cin B plus fluconazole at a daily dose of 400 mg ...

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Study of Silver Staining of Nucleolar Organiser Regions in Malignancies of Uterine Cervix.

Study of Silver Staining of Nucleolar Organiser Regions in Malignancies of Uterine Cervix.

... It has been noted that CIN lesions with low AgNOR counts are more likely to regress in comparison to CIN lesions with high AgNOR counts36 However Rowland 37 in a study on nucleolar organ[r] ...

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Silencing of E2F3 suppresses tumor growth of Her2 breast cancer cells by restricting mitosis

Silencing of E2F3 suppresses tumor growth of Her2 breast cancer cells by restricting mitosis

... and CIN [43] and Nek2 overexpression rescues back CA in HCC1954 cells expressing shE2F3 in cell culture ...and CIN do not affect fitness of these tumor ...

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A Low Power Binary to Excess-1 Code Converter Using GDI Technique

A Low Power Binary to Excess-1 Code Converter Using GDI Technique

... Code conversions are very essential in digital systems. Design of area and power efficient high speed data path logic systems are one of the most substantial areas of research in VLSI system design. In digital adders the ...

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Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function.

Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function.

... Analysis of double and triple cin null mutants: T h e three CIN genes isolated in the screening for benomyl-supersensitive mutants all have essentially identical m[r] ...

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Low Power, Area and Delay Efficient Carry Select Adder Using Bec-1 Converter

Low Power, Area and Delay Efficient Carry Select Adder Using Bec-1 Converter

... The CSLA is used in many systems to overcome the problem of carry propagation delay by independently generating multiple carries and then select a carry to generate the sum. But the CSLA is not area efficient because it ...

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