cis-acting signals
cis-Acting signals involved in termination of vesicular stomatitis virus mRNA synthesis include the conserved AUAC and the U7 signal for polyadenylation.
... In this study, we defined the cis-acting signals involved in termination of VSV mRNA synthesis. We first demonstrated that the mechanism by which upstream mRNA was synthesized and terminated was not ...
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Vesicular Stomatitis Virus mRNA Capping Machinery Requires Specific cis-Acting Signals in the RNA
... specific cis- acting signals in the RNA and describe a panel of viruses, some of which presumably now overproduce an uncapped triphos- phate ...
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cis-Acting signals that promote genome replication in rotavirus mRNA.
... the cis-acting signals in rotavirus mRNA that are important for RNA replication, gene 8 transcripts which contained internal and terminal deletions and chimeric transcripts which linked gene ...
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Polyadenylation in Rice Tungro Bacilliform Virus:cis-Acting Signals and Regulation
... poly(A) signals seem to consist of a combination of elements acting in concert to effect 3⬘-end processing at the poly(A) site or sites: cleavage usually occurs at a YA dinucleotide, under the control of a ...
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cis-Acting Signals in Encapsidation of Hantaan Virus S-Segment Viral Genomic RNA by Its N Protein
... In viruses, secondary structures such as consecutive hairpins and internal loops serve as assembly sites for numerous bio- logical activities associated with the life cycles (9). We have shown that the 5⬘ end of the ...
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Location of cis-acting signals important for RNA encapsidation in the leader sequence of human immunodeficiency virus type 2.
... recognizes cis-acting RNA signals that are unique to the viral genomic transcript (5, 6, 8, 11, 27, 33, ...major cis-acting packaging signal required for efficient encapsidation of ge- ...
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Two cis-acting signals control ribosomal frameshift between human T-cell leukemia virus type II gag and pro genes.
... Cloning of a synthetic 41-bp oligonucleotide corresponding to the gag-pro junction within a heterologous gene nef of human immunodeficiency virus type I and mutation analysis revealed th[r] ...
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Two distant upstream regions containing cis-acting signals regulating splicing facilitate 3'-end processing of avian sarcoma virus RNA.
... Processing of avian sarcoma virus RNA is relatively inefficient; approximately 15% of the viral RNA transcripts are read-through products; i.e., they are not processed at the viral polyA[r] ...
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Mutational Analysis of cis-Acting RNA Signals in Segment 7 of Influenza A Virus
... packaging signals at their termini that overlap the coding ...characterize cis-acting signals in segment 7, we introduced synonymous mutations into the terminal coding ...
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Template-dependent, in vitro replication of rotavirus RNA.
... The template dependence of this system, coupled with its ability to utilize in vitro transcripts derived from rotavirus cDNAs, will allow an analysis of cis-acting signals on the RNA tem[r] ...
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cis-Acting Packaging Signals in the Influenza Virus PB1, PB2, and PA Genomic RNA Segments
... The cis-acting signals that allow these viral RNA segments (vRNAs) to be packaged into influenza virus particles have not been fully elucidated, although the 5 ⴕ and 3 ⴕ untranslated regions (UTRs) ...
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Characterization of the cis-Acting Contributions to Avian Hepadnavirus RNA Encapsidation
... simpler cis-acting requirements for encapsidation indicates that HBV uses an alternative mecha- nism to substitute for the role of the region II element in avian ...
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cis-Acting Elements Important for Retroviral RNA Packaging Specificity
... flanking regions did not generate similar titers in PG13 cells. BB10-MShpS and BB11-SShpM contained SNV E with swapped MLV upstream and downstream flanking sequences, respectively. Both vectors generated significantly ...
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Minimal cis-Acting Elements Required for Adenovirus Genome Packaging
... the signals obtained from the analysis of the nuclear fraction from the coinfection of Ad- (Double HO) and Ad(HO gene) examining cleavage at the E3 HO ...relative signals from the intact and E3-cut genomes ...
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cis-Acting Determinants of 7SL RNA Packaging by HIV-1
... Determinants of 7SL RNA Packaging by HIV-1 nous 7SL packaging levels 12 to 14 copies 42, these data indicate that under the conditions here, six to seven molecules of Alu114 replaced the[r] ...
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Approaches for establishing the function of regulatory genetic variants involved in disease
... between cis-regulatory elements and gene promoters can be identified by chromatin con- formation capture methods, which provide mechanistic evidence to support hypotheses regarding the role of dis- tal regulatory ...
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Autoantigens interact with cis-acting elements of rubella virus RNA.
... Subsequently, cis-acting sequences within the virus genome have been determined (11, 24, 29) and shown to be necessary for both in vivo translation and RNA replication of chimeric RV-reporter gene RNAs (24, ...
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A cis-acting DNA signal for encapsidation of simian virus 40.
... Since the ability to yield CAT enzymatic activity depends not only upon gene transmission but also on gene expression, and since regulatory elements of SV40 were deleted from pSO-y-S mos[r] ...
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cis-acting elements in the U3 region of a simian immunodeficiency virus.
... A second cis-acting element was localized to sequences between -162 and -114 in U3; deletion of long terminal repeat sequences up to -114 significantly attenuated transcriptional activit[r] ...
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Evolutionary computation method for pattern recognition of cis-acting sites
... By its definition, the promoter region is located in the general vicinity of TSS, but there is also a dis- tinct region known as the enhancer. Known enhancer regions are several kilobases (kb) upstream of TSS and about ...
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