ClC-3
Original Article ClC-3 chloride channel modulates the proliferation and migration of osteosarcoma cells via AKT/GSK3β signaling pathway
... [2] Brennecke P, Arlt MJ, Campanile C, Husmann K, Gvozdenovic A, Apuzzo T, Thelen M, Born W and Fuchs B. CXCR4 antibody treatment sup- presses metastatic spread to the lung of in- tratibial human osteosarcoma xenografts ...
9
Overexpression of chloride channel-3 (ClC-3) is associated with human cervical carcinoma development and prognosis
... of ClC-3 mRNA and protein are significantly increased by 60% in paracancerous and cer- vical carcinoma ...The ClC-3 protein is expressed mainly in cervical epithelial cell cytoplasm, ...
11
The swelling activated chloride channel ClC 2, the chloride channel ClC 3, and ClC 5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells
... of ClC-3 mRNA in the kidney ...with ClC-3 antisense RNA, a signal was seen in the cortex and the outer stripe, but again only a subpopulation of cells in a given tubu- lar profile expressed ...
9
Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels
... the CLC-3 knockout mice show spon- taneous generalized tonic-clonic seizures in adult animals, but not young animals (4–5 weeks) ...of CLC-3c ...
18
Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer
... of CLC-3, we performed im- munoprecipitation (IP) combined with mass spectrom- etry (MS) in nuclear protein extracts of SGC-7901 cells with anti-XRCC5 ...the CLC-3 promoter, we pulled down the ...
15
Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival
... of ClC-3 expression on cancer-related survival in a cohort of 274 tumor patients (including 73 lung adenocarcinoma, 118 breast adenocarcinoma and 83 liver cancer) with a median follow-up of 6 months (range ...
17
Expression of the chloride channel CLC K in human airway epithelial cells
... 3, ClC-4, ClC-5, ClC-6, and ClC-7 ...identify ClC-1 expression were unsuc- cessful; this channel has previously been described as being expressed exclusively in skeletal muscle ...
6
Overexpression of chloride channel-3 predicts unfavorable prognosis and promotes cellular invasion in gastric cancer
... of CLC-3 in gastric cancer. CLC-3 is upregulated in gastric cancer tissues and cell lines, and elevated CLC-3 expression is associated with adverse clinicopathologic parameters ...
13
Ion Channels and Bone Homeostasis Imbalance
... the CLC family, ClC-3 chloride channel has been reported expressed in bone cells, and it may not only participate in cell proliferation and apoptosis of osteoclasts, but also promote new bone growth ...
6
Collaborative Innovation: Strategy To Overcome School Dropouts And Illiteracy In The Baubau City, Southeast Sulawesi Province, Indonesia
... by CLC, 3) coaching course and institution administered PKBM, 4) the provision of educational facilities of nonformal and, 5) the development of SKB ...the CLC automatically begin actively learning ...
5
Role of ClC-2 and MAPK in Gastric Barrier Function.
... homeostasis. ClC-2 knockout mice suffer from severe retinal degeneration and testicular degeneration; both of these tissues have a blood barrier and depend on the supporting tissue for nutrition (retinal pigment ...
158
ClC chloride channels
... studied ClC pores are gated (opened and closed) by transmembrane ...example, ClC-1 closes in response to hyperpolarizing (negative) membrane potentials, whereas ClC-2 ...opens. ClC-0, which ...
6
ROLE OF CHOLESTEROL LOADED CYCLODEXTRIN (CLC) IN CRYOCAPACITATION OF SPERM – A REVIEW
... with CLC increases the sperm cholesterol content 2-3 fold in bull, trout, ram and stallion sperm (Purdy and Graham, 2004; Muller et ...with CLC prior to cryopreservation improves sperm cryosurvival ...
12
A macroeconomic evaluation for cost-effective lake transportation in Malawi
... International Convention on Civil Liability for Oil Pollution Damage (CLC 1969)... Page.[r] ...
107
Comparative analysis on aac, clc and flyash concrete blocks
... In results and discussion part, the durable and bearable properties of all type of concrete is shown above graphs and tables, each type of concrete have their own comfort specialty. Therefore the comparison should be ...
8
clc is co-expressed with clf or cntfr in developing mouse muscles
... In order to confirm that muscle fibers, per se, express clc and clf, double in situ hybridization / immunohistochem- istry was carried out as described [15] on sections from E16.5 MLCnlacZ mice, which express the ...
7
The CLC-5 2Cl-/H+ exchange transporter in endosomal function and Dent's disease
... mutant CLC-5 expressed either as a trans- gene in mice (Novarino et ...converts CLC-5 from an outwardly rectifying 2Cl − /1H + exchange trans- porter into a non-rectifying Cl − conductance by uncoupling the ...
6
Localization and functional characterization of rat kidney specific chloride channel, ClC K1
... of ClC-K1 in tAL was observed in the region of both apical and basolateral plasma ...by ClC-K1 cRNA was regulated by extracellular pH and extracellular ...that ClC-K1 is responsible for the ...
11
Role of ClC-2 and NHE transport proteins in Intestinal Mucosal Barrier
... proteins ClC-2 and NHE2 in the intestinal barrier recovery ...channel ClC-2 and sodium hydrogen exchanger NHE2 are members of large ClC and NHE families respectively, and their physiological function ...
180
Coal Fired Power Plant with Chemical Looping Combustion
... RYield block converts the coal into its constituent elements and they are sent to fuel reactor. The fuel reactor is simulated using two RGibbs reactors allowing for gasification at the bottom section and reduction ...
5