CoA for coenzyme A
n-Butanol production in Saccharomyces cerevisiae is limited by the availability of coenzyme A and cytosolic acetyl-CoA
... and coenzyme A (CoA), the level of CoA might limit acetyl-CoA production as ...as CoA esters which might additionally decrease CoA ...of CoA biosynthesis could further ...
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Identification of Dephospho Coenzyme A (Dephospho CoA) Kinase in Thermococcus kodakarensis and Elucidation of the Entire CoA Biosynthesis Pathway in Archaea
... in coenzyme A (CoA) ...eukaryotic CoA synthase, TK1334 and ...in CoA auxotrophy, indi- cating that TK1697 encodes a DPCK that contributes to CoA biosynthesis in ...displayed CoA ...
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Biologically active low density lipoprotein in human peripheral lymph
... We have compared the ability of human serum and peripheral lymph to suppress the activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), to activate cholesteryl ester synthesis, and ...
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Clinical and Biochemical Phenotype in 11 Patients With Mevalonic Aciduria
... The site of the defect in patients with mevalonic aciduria is mevalonate kinase (solid square), following 3-hydroxy- 3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the rate- limiting e[r] ...
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Statins in Candidemia: clinical outcomes from a matched cohort study
... (HMG CoA) reductase inhibitors (statins) in improving outcomes bac- teremic sepsis is currently being debated with recent papers showing significantly improved survival in patients with systemic inflammatory ...
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The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle
... Kaput; CoA: coenzyme A; Cox5a: cytochrome c oxidase subunit Va; Cox6a1: cytochrome c oxidase subunit VIa polypeptide 1; Cpt2: carnitine palmitoyltransferase 2; Csrp3: cysteine and glycine-rich protein 3; ...
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Alpha-Terpineol production from an engineered Saccharomyces cerevisiae cell factory
... Glc , glucose; acetyl‑CoA, acetyl coenzyme A; tHMG1 , truncated HMG‑CoA reductase gene; HMG‑CoA, 3‑hydroxy‑3‑methylglutaryl‑CoA; IPP, isopentenyl pyrophosphate; DMAPP, dimethylallyl [r] ...
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Unavailability of liver triacylglycerol increases serum cholesterol concentration induced by dietary cholesterol in exogenously hypercholesterolemic (ExHC) rats
... metabolism—acetyl- coenzyme A [CoA] acyltransferase (Acat1), apolipoprotein B (Apob), apolipoprotein E (Apoe), fatty acid translocase (Cd36), CPT on mitochondrial inner membrane (Cpt1a), Cpt2, ...
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A STUDY OF FLUID BED GRANULATION OF PRAVASTATIN TABLET USING DESIGN OF EXPERIMENTS
... Vol 11, Issue 10, 2018 Online 2455 3891 Print 0974 2441 INTRODUCTION Pravastatin, a 3 hydroxy 3 methylglutaryl coenzyme A (HMG CoA) reductase inhibitor, is a synthetic cholesterol lowering agent that[.] ...
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Familial Reye-Like Syndrome: A Presentation of Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency
... Medium-chain acyl-coenzyme A (CoA) dehydro- genase deficiency is a recently described, autosomal recessive disorder of fatty acid oxidation that has a superficial similarity to Reye synd[r] ...
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Neuroprotective effects of vitamin D on high fat diet- and palmitic acid-induced enteric neuronal loss in mice
... Acetyl- Coenzyme A; ENS: Enteric nervous system; ER: Endoplasmic reticulum; FBS: Fetal bovine serum; GSH: Glutathione; HBSS: Hank ’ s balanced salt solution; HFD: High fat diet; ICL: Isocitrate lyase; IL: ...
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Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta-catenin pathway
... acetyl‑CoA: acetyl‑coenzyme A; APC: adenomatous polyposis coli; ARVC: arrhythmogenic right ventricular dysplasia/cardiomyopathy; BMAL1: brain and muscle aryl‑hydrocarbon receptor nuclear translocator‑like1; ...
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Recruitment of PI4KIIIβ to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1
... Members of the Enterovirus (poliovirus [PV], coxsackieviruses, and human rhinoviruses) and Kobuvirus (Aichi virus) genera in the Picornaviridae family rely on PI4KIII  (phosphatidylinositol-4-kinase III  ) for ...
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Regulation of acylcoenzyme A Cholesterol acyltransferase and 3 hydroxy 3 methylglutaryl coenzyme A reductase activity by lipoproteins in the intestine of parabiont rats
... hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase activity) and esterification (acylcoenzyme A/cholesterol acyltransferase [ACAT] activity) by lipoproteins and micellar ...
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Epigenetic assays for chemical biology and drug discovery
... Acetyl-CoA: Acetyl-coenzyme A; ADME: Absorption, Distribution, Metabolism and Excretion; APC: Allophycocyanin; BODIPY: 4,4-Difluoro-4-bora-3a,4a-diaza- s-indacene; BRD4: Bromodomain-cont[r] ...
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Insulin receptor membrane retention by a traceable chimeric mutant
... Recently we studied insulin and IGF-II endocytosis dy- namics in living cells through IR-B [31,32]. Here we report novel IR-B chimeras containing an extracellular tag suit- able to be covalently modified at the plasma ...
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Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells
... AA, amino acid; ACACA, Acetyl-coenzyme A carboxylase alpha; ACSL1, Acyl-CoA synthetase long-chain family member 1; ACSS2, Acyl-CoA synthetase short-chain family member 2; AGPAT6, ...
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Prevalence of Fatty Liver Changes and Other Various Adverse Effects in Patients Taking Tablet Atorvastatin: A Cross Sectional Observational Study
... APPENDIX-1 LIST OF ABBREVIATIONS HMG-COA - 3- Hydroxy -3- methyl glutaryl coenzyme A ATP - Adenosine tri phosphate ACC - Acetyl coa carboxylase NASH - Non alcoholic steato hepatitis DCLD[r] ...
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Emerging role of lipid metabolism alterations in Cancer stem cells
... ACADM: Acyl-CoA dehydrogenase medium chain; ALDH1: Aldehyde dehydrogenase isoform 1; CoA: Acetyl coenzyme A; CSCs: Cancer stem cells; EGFR: Epidermal growth factor receptor; EMT: Epithel[r] ...
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Genetic deficiency of short chain acyl coenzyme A dehydrogenase in cultured fibroblasts from a patient with muscle carnitine deficiency and severe skeletal muscle weakness
... dehydrogenase. These data demonstrated that medium-chain acyl-CoA dehydrogenase accounted for 50% of the activity towards the short-chain substrate, butyryl-CoA, under these conditions, but that antibody ...
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