cobra venom
Cytotoxic activity of NN 32 toxin from Indian spectacled cobra venom on human breast cancer cell lines
... Background: Breast cancer is the most common cancer which causes significant morbidity and mortality among women worldwide. Lack of medical facilities for early detection, therapeutic strategies for treatment and side ...
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Chemotactic activity derived from interaction of factors D and B of the properdin pathway with cobra venom factor or C3B
... Interaction of D (the activated form of D) and B, factors of the properdin pathway, with C3b (the major cleavage fragment of C3) generates a convertase, C3B, which cleaves C3 and initiates the terminal complement ...
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HISTOLOGICAL STUDY ON THE PROTECTIVE EFFECTS OF TAMARIND SEED EXTRACT ON COBRA VENOM IN MICE
... toxic cobra venom proteins and used against snake envenomation in folkloric ...King Cobra Venom (KCV) in the muscles, liver, and the kidneys of experimentally envenomed ...
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Reduction by Cobra Venom Factor of Myocardial Necrosis after Coronary Artery Occlusion
... leukocytes. Cobra venom factor specifically cleaves C3 activity via activation of the alternative (properdin) complement ...injury, cobra venom factor might reduce tissue damage after acute ...
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Escherichia Coli Bacteremia in the Squirrel Monkey I EFFECT OF COBRA VENOM FACTOR TREATMENT
... constituent of cobra venom, and the influence of cobra factor (CoF) treatment on the course of Escherichia coli bacteremia was studied. Striking neutropenia occurred rapidly in control animals while ...
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Inhibition of Toxic Effects of Viper and Cobra Venom by Indian Medicinal Plants
... snakes found throughout India and a large number of deaths occur due to envenomation by these snakes. The antiserum is the only therapeutic agent available for the treatment of snakebite and does not provide enough ...
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EFFECT OF SILVER NANO PARTICLES SYNTHESIZED OF TRICHODESMA INDICUM AGAINST NAJA NAJA (COBRA) VENOM
... anti venom activity was ...of cobra venom at 10 and 20 ...the venom activities of cobra in blood ...the cobra venom has confirmed inhibitory effects in in vitro ...
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Evidence for role of hydroxyl radical in complement and neutrophil dependent tissue injury
... by cobra venom factor (CVF), we demonstrated that pretreatment of animals with human milk apolactoferrin (in its native or derivatized form), but not iron-saturated lactoferrin, provides significant ...
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Electroporation and electropermeabilization of lipid bilayer membranes in the course of snakes’ venom intoxication
... viper venom in organism lead to increasing of the electrical resistance of BLMs from liver and muscle lipids approximately on a sequence, while the BLMs from brain lipids has not shown a noticeable differences of ...
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Effect of Mucuna pruriens Seed Extract Pretreatment on the responses of spontaneously beating Rat Atria and Aortic Ring to Naja sputatrix (Javan Spitting Cobra) Venom
... spitting cobra) venoms, and the protective effect involved immunological neutralization of the venom ...against cobra venom toxicity, the actions of Naja sputatrix venom on spontaneously ...
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C1r deficiency: an inborn error associated with cutaneous and renal disease
... The studies of sera from two siblings with C1r deficiency are described. The brother (18 yr old) has shown clinical manifestations resembling lupus erythematosus for 5 yr, and the sister (24 yr old) has had arthralgia ...
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Development of red hen egg yolk antibodies against the Naja naja (Indian cobra) venom and its neutralisation studies
... U16 plates were coated with concentration of cobra venom and incubated at 4°C overnight. Subsequently the coated plates were washed with Phosphate Buffer Saline with Tween 20 (PBST) 4 times. The uncoated ...
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How the cobra got its flesh-eating venom: cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting
... The venom of this species has also undergone a proteomic streamlining (relative to that of other Naja—Figure 8) in a manner analogous to the evolution of simplified venoms in other aquatic elapid snakes—sea kraits ...
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A NEUROTOXIN ISOLATED AND PURIFIED FROM THE VENOM OF NAJA NAJA (INDIAN COBRA) ENVISAGED AS A POTENT THERAPEUTIC TOOL TO TREAT MOVEMENT DISORDERS
... (Indian cobra) is one of the most venomous elapid snakes found throughout India responsible for the majority of fatal snake bite ...(Indian cobra) neurotoxin causes postsynaptic neuromuscular blockade as ...
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Investigating venom synthesis: exploring the composition, variation and gene expression dynamics of Bitis arietans venom
... of venom proteins, we exploited the unusual stability of messenger RNA in lyophilised snake venoms as an alternative source of transcriptionally active mRNA to venom gland tissues, thus avoiding the ...
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Cost utility of COBRA light versus COBRA therapy in patients with early rheumatoid arthritis: the COBRA light trial
... The main limitation is the fact that actual costs on etanercept use did not properly represent the costs if the protocol had been followed as intended, as shown in the sensitivity analysis. Given the large costs of ...
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The protective effects of Mucuna pruriens seed extract against histopathological changes induced by Malayan cobra (Naja sputatrix) venom in rats
... Velvet beans (Mucuna spp.) are found in Asia (including Malaysia), America and Africa. The beans have been prescribed by traditional practitioners in Nigeria as an oral prophylactic for snakebites. It is claimed that ...
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The buccal buckle: the functional morphology of venom spitting in cobras
... in venom pressure ...of venom, was also supported by our experimental ...the venom spitting behaviors ...the venom stream ...to venom flow within the fang sheath is evident in the ...
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Comparative venom gland transcriptomics ofNaja kaouthia(monocled cobra) from Malaysia and Thailand: elucidating geographical venom variation and insights into sequence novelty
... Enriched poly(A) + mRNA isolated from the total venom gland RNA was used for cDNA construction. Following purification, the mRNA isolated was fragmented in standard buffers containing divalent cations (Zn 2+ ) ...
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3D flow in the venom channel of a spitting cobra: do the ridges in the fangs act as fluid guide vanes?
... The steps for the generation of the transparent model are given in Fig. 1. With the aid of the MCT-data, a negative form was created out of wax. In a further step, silicon was casted around the wax form and the wax then ...
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