code Binding interaction with amino acid residue
Single Amino Acid Change in Metallothionein Metal-Binding Cluster Influences Interaction with Cisplatin
... the interaction of a cytostatic with biomolecules synthesized by tumour ...of interaction between 23 sulphur-rich fragments of the metal-binding protein metallothionein and cisplatin was ...results, ...
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Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition
... by binding to terminal sialic acid (SA) residues on host ...accumulates amino acid substitutions that allow IAV to escape immunity through a mechanism known as antigenic ...of amino ...
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Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition
... amino acid substitutions at residue 145 were tested for receptor binding specificity with varying 713. concentrations of SAα2-3Gal (α2-3-linked SA) or SAα2-6Gal (α2-6-linked SA).[r] ...
43
Amino acid fermentation at the origin of the genetic code
... can amino acylate at arbitrary positions of the RNA, not only at the end of ...of binding of the amino acids to the handles? I suppose De Vladar thinks (with me also) that the link was covalent at ...
20
Prediction of RNA binding sites in proteins from amino acid sequence
... RNA binding sites on the L15 ...RNA binding domain to be detected, but at the loss of specificity (data not ...RNA binding motif (dsRBM) domain of the Xenopus dsRNA binding protein A bound to ...
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Predicting Protein-Protein Interaction Sites From Amino Acid Sequence
... which amino acid residues are located in the interaction site? Many investigators have analyzed the characteristics of protein-protein interaction sites to gain insight into the molecular ...
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Host-Selected Amino Acid Changes at the Sialic Acid Binding Pocket of the Parvovirus Capsid Modulate Cell Binding Affinity and Determine Virulence
... V325 residue in modulating SA binding in a manner similar to I362 and ...SA interaction with the MVMp capsid will require cocrystallization of the wt MVMp and mutant capsids with longer SA conjugates ...
11
Identification of Amino Acid Residues of Influenza Virus Nucleoprotein Essential for RNA Binding
... of amino acids involved, and finally the crucial residues by ...and amino acid sequencing of NP that had been UV cross linked to radiolabelled RNA showed that protein- RNA contacts occur throughout ...
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Comparing Kernels For Predicting Protein Binding Sites From Amino Acid Sequence
... a residue is in the interaction ...of amino acids within a window of 11 contiguous residues, corresponding to the target residue flanked by five sequence neighbors residues on each ...target ...
6
Amino Acid Residue-Specific Neutralization and Nonneutralization of Hepatitis C Virus by Monoclonal Antibodies to the E2 Protein
... shared binding specificity for key amino acid residues, including W 437 , L 438 , L 441 , and F 442 , within the same epitope of the E2 ...of amino acid ...
9
A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome
... Results: Using a targeted next-generation sequencing array of 38 ichthyosis-associated genes on a large cohort of 180 ichthyosis patients from a primarily consanguineous background, a previously unreported homozygous ...
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Unnatural amino acid incorporation to rewrite the genetic code and RNA-peptide interactions
... Abstract Efforts to reengineer the protein synthesis apparatus should expand our fundamental understanding of the central macromolecular synthesis machinery inside all cells. The UAG stop codon has often been referred to ...
119
Amino Acid Biophysical Properties in the Statistical Prediction of Peptide-MHC Class I Binding
... peptides on two sets of position specific structural param- eters, namely Isotropic Surface (ESI), area and Electronic Charge Index (ECI). Though none of regression coeffi- cient themselves were statistically significant ...
11
A Single Amino Acid Residue Change in the P Protein of Parainfluenza Virus 5 Elevates Viral Gene Expression
... the amino acid residue that plays a critical role in the elevated gene expression to serine at position ...this residue plays a critical role in modulating virus RNA replica- ...(PLK1) ...
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A Single-Amino-Acid Substitution of a Tyrosine Residue in the Rubella Virus E1 Cytoplasmic Domain Blocks Virus Release
... involves interaction of the E1 tail with other viral structural proteins, possibly ...tyrosine residue in the cytoplas- mic domain of E2 glycoprotein has been identified as being essential for the ...
8
A Single Amino Acid Substitution at Residue 218 of Hemagglutinin Improves the Growth of Influenza A(H7N9) Candidate Vaccine Viruses
... The residue at position 218 of HA is at the interfaces of monomers, whereas G218E was previously reported to increase H3 HA membrane fusion pH that decreases HA acid stability ...HA acid stability. ...
15
Amino acid residue burial & co-evolution in proteins
... the residue numbers for the start and end points in the PDB ...the residue number can be ...corresponding amino acid sequences for each entry are retrieved and Tre is used to try to locate the ...
282
Role for the P4 amino acid residue in substrate utilization by the poliovirus 3CD proteinase.
... In cells infected with Sel-lC-10 at 37°C (data not shown) or 39°C, cleavage of the P1 precursor occurred at both the inserted Q-G amino acid pair and the wild-type VP3-VP1 cleavage site [r] ...
13
Amino Acid + Amino Acid + Amino Acid Proteins (many peptide linkages)
... − To 1 mL amino acid solution in a test tube, add 2-3 drops of ninhydrin reagent.. - Put in a boiling water bath and observe the formation of a purple color.[r] ...
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An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance
... L J Baier, … , C Bogardus, M Prochazka J Clin Invest. 1995;95(3):1281-1287. https://doi.org/10.1172/JCI117778. The intestinal fatty acid binding protein locus (FABP2) was investigated as a possible genetic ...
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