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Cognitive changes in normal aging

Regional and Global Changes in Cerebral Diffusion with Normal Aging

Regional and Global Changes in Cerebral Diffusion with Normal Aging

... with normal aging and may pro- vide a global assessment of normal age-related changes and serve as a standard for comparison with neurodegenerative ...the aging process (1). Over- ...

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Changes in Brain Morphology in Alzheimer Disease and Normal Aging: Is Alzheimer Disease an Exaggerated Aging Process?

Changes in Brain Morphology in Alzheimer Disease and Normal Aging: Is Alzheimer Disease an Exaggerated Aging Process?

... voxel-based morphometric method is used to avoid subjectivity and dependence on a priori hypothesis and to adopt the principle of data-driven analysis. Raz et al also reported that the most substantial age-related ...

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OXIDATIVE CHANGES AND COGNITIVE FUNCTION DECLINE IN AGING RATS

OXIDATIVE CHANGES AND COGNITIVE FUNCTION DECLINE IN AGING RATS

... microcentrifuge tube were immediately pipetted onto a normal point agarose layer on a glass slide, covered using a coverslip, and allowed to solidify. The slide was then immersed in cold lysing solution (2.5 M ...

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A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

... neurosynaptic changes appear before tau-mediated neuronal injury or brain structure changes and are one of the earliest markers of preclinical AD ...early changes and may advance the early detection ...

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A Cognitive Electrophysiological Signature Differentiates Amnestic Mild Cognitive Impairment from Normal Aging

A Cognitive Electrophysiological Signature Differentiates Amnestic Mild Cognitive Impairment from Normal Aging

... neurosynaptic changes appear before tau-mediated neuronal injury or brain structure changes and are one of the earliest markers of preclinical AD ...early changes and may advance the early detection ...

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Cognitive plasticity in normal aging and mild cognitive impairment. Shedding light on prefrontal activation

Cognitive plasticity in normal aging and mild cognitive impairment. Shedding light on prefrontal activation

... 7 Cognitive training: Implications In chapter 4, we concluded that WM training led to improved performance in the WM domain in healthy older adults and patients with ...to cognitive domains other than WM, ...

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Use of the Internet as a prevention tool against cognitive decline in normal aging

Use of the Internet as a prevention tool against cognitive decline in normal aging

... these cognitive skills decline during the process of ...that cognitive aging varies among different individuals, there are some common ...that changes in the cognitive domain are based ...

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Systematic changes in position sense accompany normal aging across adulthood

Systematic changes in position sense accompany normal aging across adulthood

... Although other studies have used instruments such as dynamometers [49], motion-capture systems [50], incli- nometers [51], and light exoskeleton systems [52] to measure position sense, our robotic device offers a num- ...

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White matter correlates of cognitive domains in normal aging with diffusion tensor imaging

White matter correlates of cognitive domains in normal aging with diffusion tensor imaging

... Aging is accompanied by deterioration of cognitive functions, as well as changes in gray and white matter integrity. Cross sec- tional and longitudinal behavioral studies have found significant ...

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Sex differences in obesity and cognitive function in a cognitively normal aging Chinese Han population

Sex differences in obesity and cognitive function in a cognitively normal aging Chinese Han population

... physiological changes in hormonal status during and after menopause and sex, due to changes in individual and social behavior, such as modifications in socioeconomic status and adoption of unhealthy ...for ...

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Aging, cognitive abilities and retirement

Aging, cognitive abilities and retirement

... and normal retirement, while the blue and red areas indicate changes in the eligibility rules for the cohorts in our ...Major changes occurred Italy, while smaller changes occurred in Austria, ...

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Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging

Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging

... complement clinical assessment methods such as cogni- tive and psychometric tests [3,5,8,9]. If they are devel- oped, validated signatures for AD will enable a rapid identification of prodromal AD patients and could po- ...

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Prefrontal activation may predict working-memory training gain in normal aging and mild cognitive impairment

Prefrontal activation may predict working-memory training gain in normal aging and mild cognitive impairment

... of aging-related compensatory brain acti- vation may help to predict and explain training-induced changes in brain activation in normal aging and ...MCI. Normal aging is ...

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Prefrontal activation may predict working-memory training gain in normal aging and mild cognitive impairment

Prefrontal activation may predict working-memory training gain in normal aging and mild cognitive impairment

... of aging-related compensatory brain acti- vation may help to predict and explain training-induced changes in brain activation in normal aging and ...MCI. Normal aging is ...

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Regional Differences and Metabolic Changes in Normal Aging of the Human Brain: Proton MR Spectroscopic Imaging Study

Regional Differences and Metabolic Changes in Normal Aging of the Human Brain: Proton MR Spectroscopic Imaging Study

... The present study investigated whether metabol- ic measurements can change in normal brain during the early period of aging, ranging from 21 to 61 years. To test this hypothesis, the metabolite distri- ...

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Adult hippocampal neurogenesis and cognitive aging

Adult hippocampal neurogenesis and cognitive aging

... Espacial. Aging is a normal developmental process associated with neurobiological changes leading to cognitive alterations with preserved, impaired, and enhanced ...age-related ...

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Successful aging: The role of cognitive gerontology

Successful aging: The role of cognitive gerontology

... that cognitive tasks can be sensitive to relatively small differences or changes in normal individuals whereas clinical tools are designed to detect exceptional functioning and most individuals score ...

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Task related brain oscillations in normal aging

Task related brain oscillations in normal aging

... healthy aging people revealed increased P300 amplitude and decreased P300 latency in respond- ing to the auditory oddball task ...the changes of frequency bands and oscillatory changes in different ...

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A voxel-based morphometric study of age- and sex-related changes in white matter volume in the normal aging brain

A voxel-based morphometric study of age- and sex-related changes in white matter volume in the normal aging brain

... Introduction Normal brain aging is a physiological process accompanied by declines in the function of multiple systems in the body, including age-related cognitive decline, which is manifested as a ...

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Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment

Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment

... mild cognitive impairment (aMCI), a significant risk factor for Alzheimer's disease (AD), is characterized by impaired episodic memory function and is generally considered to represent a transitional state between ...

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