coiled coil domain
The role of the Cronobacter sakazakii ProP C-terminal coiled coil domain in osmotolerance
... C-terminal domain of other osmolyte transporters, such as BetP (Corynebacterium glutamicum) and OpuA (Bacillus subtilis), was demonstrated to be im- portant for the activation of these proteins during an in- ...
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The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling
... apical domain of infected polarized enterocytes and favor the polarized apical exit of viral ...binding domain is unable to promote microfila- ment remodeling by itself; the coiled-coil ...
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An Antiviral Peptide Targets a Coiled-Coil Domain of the Human T-Cell Leukemia Virus Envelope Glycoprotein
... core coiled-coil structure of HTLV-1 ...core coiled-coil domain of HIV Env (8, 15, 25, 38, ...central coiled-coil of HTLV-1 TM, we first generated recombinant TM-derived ...
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Coiled coil domain containing 109B is a HIF1α regulated gene critical for progression of human gliomas
... [5]. Coiled coils are involved in signal-transducing events and act as a molecular recognition ...of coiled-coil domain containing proteins influences the migration, invasion and prolifera- ...
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The Specificity of TRIM5α-Mediated Restriction Is Influenced by Its Coiled-Coil Domain
... the coiled-coil do- main and is required for capsid binding (12, ...monkey coiled-coil domain to support TRIM5 ␣ -mediated restriction of B- and Mo-MLV was un- likely to be caused by a ...
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The Coiled-Coil Domain of the Adenovirus Type 5 Protein IX Is Dispensable for Capsid Incorporation and Thermostability
... the coiled-coil region ( ⌬ 100-114) did not have a negative effect on the incorporation of pIX into the virus ...the coiled-coil ( ⌬ 100-114) region were as thermostable as wt ...conserved ...
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Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4
... Rotavirus (RV) nonstructural protein 4 (NSP4) is a virulence factor that disrupts cellular Ca 2ⴙ homeostasis and plays multiple roles regulating RV replication and the pathophysiology of RV-induced diarrhea. Although its ...
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Baculovirus FP25K Localization: Role of the Coiled-Coil Domain
... From domain prediction, it is apparent that AcMNPV FP25K has conserved N- terminal coiled-coil, putative actin binding helix, and nucleic acid binding ...N-terminal coiled-coil ...
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Mutational Analysis of Residues in the Coiled-Coil Domain of Human Immunodeficiency Virus Type 1 Transmembrane Protein gp41
... the coiled-coil domain (residues 553 to 595, here- after referred to as the heptad repeat) near the fusion peptide of gp41 that potentially affect both the stability of the coiled- coil ...
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Oligomerization of Hantavirus Nucleocapsid Protein: Analysis of the N-Terminal Coiled-Coil Domain
... trimerization domain (amino acid residues 1 to 77) of Tula hantavirus using computer modeling, mammalian two-hybrid assay, and immunofluorescence ...antiparallel coiled- coil stabilized by ...
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Extending the self-assembly of coiled-coil hybrids
... -Helical coiled coils are remarkable not only for their quantity, but for the range of functions that they exhibit in ...of coiled coils – two or more - helices binding together in a specific manner – means ...
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Association between single nucleotide polymorphism rs11057401 of CCDC92 gene and the risk of coronary heart disease (CHD)
... CCDC92: Coiled-coil domain containing 92; CHD: Coronary heart disease; FPG: Fasting plasma glucose; GWAS: Genome-wide association study; HDL-C: High-density lipoprotein cholesterol; HWE: ...
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Characterization of an Amino-Terminal Dimerization Domain from Retroviral Restriction Factor Fv1
... C-terminal domain direct the specificity of restriction of N- or B-tropic MLV (3) and that this specificity is targeted toward the viral capsid (7, 20, 29, 41, 44, ...PRYSPRY domain at the C-terminal region ...
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PINK1-PARK2-mediated mitophagy in COPD and IPF pathogeneses
... fun14 domain con- taining 1 (FUNDC1) have been demonstrated to be specific receptors for mitophagic recognition during red blood cell maturation, metabolic stress, and ...and coiled-coil ...
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Analyses of protein corona on bare and silica-coated gold nanorods against four mammalian cells
... sucrase-isomaltase, intestinal Vitamin D-binding protein precursor Transmembrane and coiled-coil domain-containing protein 2 l-lactate dehydrogenase c isoform 1 complement factor B precu[r] ...
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The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury
... SNPs rs7136446 and rs972936 have been studied in several human traits and diseases. Huuskonen et al. found that rs7136446 was associated with maximal force produc- tion and body composition [53], while Aberg et al. ...
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Investigating the biological role of human NEIL3
... Homo sapiens coiled-coil domain containing 88A CCDC88A, transcript variant 2, mRNA Homo sapiens solute carrier family 25 mitochondrial carrier; phosphate carrier, member 3 SLC25A3, nucle[r] ...
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Genome-wide discovery and characterization of long noncoding RNAs in patients with multiple myeloma
... In addition, the present study also found the differential expression of coiled-coil domain-containing 26 (CCDC26). CCDC26 is located on chromosome 8q24.21. Several studies have demonstrated that ...
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Mcp4, a Meiotic Coiled-Coil Protein, Plays a Role in F-Actin Positioning during Schizosaccharomyces pombe Meiosis
... C-terminal coiled-coil domain of Mcp4 is required for proper localization of this protein during ...The coiled-coil motif is indicated by the black ...
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The role of the NLRP3 inflammasome in gout.
... recruitment domain; CC, coiled-coil domain; CINCA/NOMID, chronic infantile neurologic, cutaneous, and articular syndrome/neonatal onset multisystem inflam- matory disease; CPPD, calcium ...
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