collagen VI
Adipocyte derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment
... cleaved collagen VI using an automated slide stainer (DakoCytomation) with a catalyzed signal amplification system ...anti–collagen VI antibody specific to the C-terminal of the α3 subunit was ...
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A collagen VI–dependent pathogenic mechanism for Hirschsprung’s disease
... of collagen VI trimeric monomers (24, 25); and (d) high levels of mature extracellular collagen VI microfilaments are clearly detrimental for eNCC migration (this ...increased collagen ...
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FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
... While collagen VI begins to emerge as an important regulator of cell migration, reports on its direction of ef- fect, inhibiting or promoting migration, are controversial ...instance, collagen ...
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Human adipose-derived stem cell transplantation as a potential therapy for collagen VI-related congenital muscular dystrophy
... several collagen genes was detected, in- cluding those coding for the α1 and α2 chains of colla- gen I, the α2 chain of collagen IV, the α1 and α2 chains of collagen V, the α1 and α2 chains of ...
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Authentication of collagen VI antibodies
... Four of the five antibodies against the α1 chain pro- duced a signal on skeletal muscle sections, with ab199720 (abcam) (Fig. 2, panels E, F) and 17023-1-AP (Protein- Tech Group) (M and N) detecting highest levels in the ...
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<p>The Biological Role of the Collagen Alpha-3 (VI) Chain and Its Cleaved C5 Domain Fragment Endotrophin in Cancer</p>
... that collagen VI is expressed in a variety of human tissues and distributed among connective tissues such as skin, blood vessels, and adipose tissue; 10,26 nervous tissues; 27,28 and muscle ...lagen ...
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A recurrent COL6A1 pseudoexon insertion causes muscular dystrophy and is effectively targeted by splice-correction therapies
... Screening for the COL6A1 +189C>T mutation. In Cummings et al. (22), we initially reported a pseudoex- on insertion in RNA sequencing reads from muscle specimens of 4 index patients (US1, US2, UK1, and UK2; ...
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Tumor-associated collagen signatures: pushing tumor boundaries
... the collagen gel in between, from random formation to a lin- ear pattern ...of collagen gels is done by MDA-MB-231 cells, and a recent study also shows that linear de novo formation of collagen by a ...
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Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology
... Type VI colla- gen has many roles covering structural purposes to more cell-specific functions including regulation of apoptosis, proliferation, differentiation and maintenance of cell stemness ...[97]. ...
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ColVI myopathies: where do we stand, where do we go?
... Collagen VI myopathies, caused by mutations in the genes encoding collagen type VI (ColVI), represent a clinical continuum with Ullrich congenital muscular dystrophy (UCMD) and Bethlem ...
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Hirschsprung’s disease, Down syndrome, and missing heritability: too much collagen slows migration
... human collagen VI are on chro- mosome 21 (COL6A1 and COL6A2), and COL6A1 is within a region defined as impor- tant for HSCR risk in human partial trisomy analyses ...These collagen genes are ...
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The inhibitory effects of camptothecin, a topoisomerase I inhibitor, on collagen synthesis in fibroblasts from patients with systemic sclerosis
... Dermal fibroblasts were obtained from patients with diffuse SSc and healthy volunteers. The patient group consisted of 18 individuals (10 females and 8 males), whose mean age was 39.5 ± 2.6 years (range 30–51). All ...
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Simplified Extraction and Characterization of Acetic Acid Solubilized Type I Collagen Derived from Solea Solea Skin and Wistar Rat Tails for Biomedical and Biotechnological Applications
... of collagen depends on the temperature and increase exponentially with the augmentation of the used acetic acidity ...conductive collagen gel scaffolds, but also produce collagen scaffolds compatible ...
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Randomized placebo controlled double blind phase II study of zaltoprofen for patients with diffuse type and unresectable localized tenosynovial giant cell tumors: a study protocol
... A tenosynovial giant cell tumor (TGCT) is a locally ag- gressive benign neoplasm arising from intra- or extra-articular tissue. A localized extra-articular TGCT, also known as a giant cell tumor of the tendon sheath, ...
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Ascorbic acid enhances adipogenesis of 3T3-L1 murine preadipocyte through differential expression of collagens
... in collagen biosynthesis has been prevented by its structural ...on collagen regulation was inhibited by EDHB in late phase of adipogenesis, accumulated lipid droplet was removed from fully differentiated ...
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Collagen gene expression by cultured human skin fibroblasts Abundant steady state levels of type VI procollagen messenger RNAs
... Previous studies have suggested that procollagen types I and III are the major collagenous gene products of cultured human skin fibroblasts. In this study the expression of 10 different genes, encoding the subunit ...
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VI
... Then I would like to put it into that gorgeous body of water, watch it drift away and finally reach you, one day far in the future.. I would want for it to peacefully float up to you,[r] ...
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VOLUME – VI (2016), ISSUE – VI (JUNE)
... At the school level, teacher commitment is empirically supported as an influential factor for school effectiveness, teacher satisfaction and teacher retention (Fresko et al., 1997; Nir,[r] ...
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Type 1 regulatory T cells specific for collagen type II as an efficient cell based therapy in arthritis
... (closed circles; n = 9) at day 20 postimmunization. After the T-cell infusions, the mice were clinically monitored every other day. (A) Graphed mean ± SEM data of the arthritis severity scores are shown. Differences were ...
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Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat
... a collagen scaffold (collagen/PBS), En-PSCs loaded on a collagen scaffold (collagen/En-PSCs), En-PSCs with low CYR61 expression loaded on a collagen scaffold (collagen/si-CYR61 ...
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