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comparative effectiveness

Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study

Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study

... Background: We designed and initiated a pilot comparative effectiveness study for juvenile localized scleroderma (jLS), for which there is limited evidence on best therapy. We evaluated the process we used, ...

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Comparative effectiveness of electro acupuncture plus lifestyle modification treatment for patients with simple obesity and overweight: study protocol for a randomized controlled trial

Comparative effectiveness of electro acupuncture plus lifestyle modification treatment for patients with simple obesity and overweight: study protocol for a randomized controlled trial

... CER: Comparative Effectiveness Research; CI: confidence interval; CONSORT: Consolidated Standards of Reporting Trials; DALYs: Disability-adjusted Life-Years; EGD: Effectiveness Guidance Document; ...

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A comparative effectiveness trial of postoperative management for lumbar spine surgery: changing behavior through physical therapy (CBPT) study protocol

A comparative effectiveness trial of postoperative management for lumbar spine surgery: changing behavior through physical therapy (CBPT) study protocol

... This study is being funded by PCORI (CER-1306-01970). The authors would like to acknowledge the study ’ s Advisory Board for their contribution across the 5 phases of this comparative effectiveness study, ...

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CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department

CLUE: a randomized comparative effectiveness trial of IV nicardipine versus labetalol use in the emergency department

... randomized comparative effectiveness trial directly evaluating the use of a nicardipine infusion to bolus labetalol in the ED management of acute hyperten- sion, we demonstrated that patients receiving ...

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Immediate versus conditional treatment of uncomplicated urinary tract infection   a randomized controlled comparative effectiveness study in general practices

Immediate versus conditional treatment of uncomplicated urinary tract infection a randomized controlled comparative effectiveness study in general practices

... a comparative effectiveness study with the aim to investi- gate whether the use of antibiotics for uncomplicated UTI could be reduced by initial treatment with ibupro- fen, reserving antibiotic treatment to ...

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Comparative Effectiveness of Interventions for Children Exposed to Nonrelational Traumatic Events

Comparative Effectiveness of Interventions for Children Exposed to Nonrelational Traumatic Events

... METHODS: We assessed research on psychological and pharmacolog- ical therapy as part of an Agency for Healthcare Research and Quality – commissioned comparative effectiveness review. We conducted focused ...

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The comparative effectiveness and cost-effectiveness of ranibizumab for neovascular macular degeneration revisited

The comparative effectiveness and cost-effectiveness of ranibizumab for neovascular macular degeneration revisited

... Value-Based Medicine ® (VBM) [4, 14–17] is a meth- odology of cost-utility analysis employing standardized inputs to determine the patient value gain and financial value gain conferred by healthcare interventions. ...

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Study protocol for a comparative effectiveness trial of two models of perinatal integrated psychosocial assessment: the PIPA project

Study protocol for a comparative effectiveness trial of two models of perinatal integrated psychosocial assessment: the PIPA project

... around effectiveness, efficiency and acceptability of a psychosocial screening program from the perspective of the maternity sectors, indirect patient costs associated with travel etc will not be included, nor ...

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Organizational culture and climate as moderators of enhanced outreach for persons with serious mental illness: results from a cluster-randomized trial of adaptive implementation strategies

Organizational culture and climate as moderators of enhanced outreach for persons with serious mental illness: results from a cluster-randomized trial of adaptive implementation strategies

... comparative effectiveness of two implementation strat- egies, Enhanced vs. Standard REP, or two sequences of im- plementation strategies, Immediate vs. Delayed Enhanced REP, among sites not initially ...

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Singler_Current_Issues_and_Trends_in_CER_masters_paper_final_final.pdf

Singler_Current_Issues_and_Trends_in_CER_masters_paper_final_final.pdf

... In the summer of 2014, I completed my master’s practicum within the Scientific Affairs unit of the Real-World Late Phase Research division at Quintiles, the leading contract research organization. This unit is led by ...

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Adrien_Lokangaka_MP_Final.pdf

Adrien_Lokangaka_MP_Final.pdf

... therapy for the treatment of serious bacterial infection in neonates and young infants. The results of that study suggest that these infections could be treated effectively in health centers or homes. However, each of ...

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Assessment of a method to detect signals for updating systematic reviews

Assessment of a method to detect signals for updating systematic reviews

... AHRQ Comparative Effectiveness Review program had produced 13 comparative effectiveness reviews (CERs), a subcategory of systematic reviews, by 2009, 11 of which were assessed in 2009 using a ...

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Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans

Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans

... This pilot study assessed the feasibility of using stan- dardized CARRA CTPs for untreated systemic JIA, 90% of whom had disease onset less than 4 months prior to treatment, to evaluate the comparative ...

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Health-related quality of life in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in a naturalistic outpatient setting

Health-related quality of life in patients with depression treated with duloxetine or a selective serotonin reuptake inhibitor in a naturalistic outpatient setting

... These analyses were repeated for subgroups of PPS + and PPS - patients, respectively, to examine whether the comparative effectiveness of duloxetine versus an SSRI differ between PPS + and PPS - patients. ...

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Program ACTIVE II: Design and Methods for a Multi-Center Community-Based Depression Treatment for Rural and Urban Adults with Type 2 Diabetes

Program ACTIVE II: Design and Methods for a Multi-Center Community-Based Depression Treatment for Rural and Urban Adults with Type 2 Diabetes

... the comparative effectiveness of a combination of CBT and exercise using a CErN approach in which community fitness and mental health partners provide depression treatment to study ...the comparative ...

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High prevalence but limited evidence in complementary and alternative medicine: guidelines for future research

High prevalence but limited evidence in complementary and alternative medicine: guidelines for future research

... the comparative effectiveness of CAM; the effects of meaning and context on CAM out- comes; and different models for integrating CAM into existing health care ...including comparative ...

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A COMPARATIVE STUDY OF THE EFFECTIVENESS OF VYGOTSKY’S CONCEPT OF ZONE OF PROXIMAL DEVELOPMENT AND TRADITIONAL METHOD FOR TEACHING MATHEMATICS AT ELEMENTARY LEVEL

A COMPARATIVE STUDY OF THE EFFECTIVENESS OF VYGOTSKY’S CONCEPT OF ZONE OF PROXIMAL DEVELOPMENT AND TRADITIONAL METHOD FOR TEACHING MATHEMATICS AT ELEMENTARY LEVEL

... the comparative effectiveness of Vygotsky's Concept of Zone of Proximal Development and Traditional Method for teaching Mathematics at Elementary ...

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Review of the registration of clinical trials in UMIN CTR from 2 June 2005 to 1 June 2010   focus on Japan domestic, academic clinical trials

Review of the registration of clinical trials in UMIN CTR from 2 June 2005 to 1 June 2010 focus on Japan domestic, academic clinical trials

... Abbreviations CER: comparative effectiveness research; CONSORT: Consolidated Standards of Reporting Trials; EFPIA: European Federation of Pharmaceutical Industries and Associations; FDA:[r] ...

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Network meta-analysis incorporating randomized controlled trials and non-randomized comparative cohort studies for assessing the safety and effectiveness of medical treatments: challenges and opportunities

Network meta-analysis incorporating randomized controlled trials and non-randomized comparative cohort studies for assessing the safety and effectiveness of medical treatments: challenges and opportunities

... permit comparative safety and effectiveness assessment of medical prod- ucts across multiple databases without creation of a central data warehouse [34, 36, ...

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Conceptual Design of a Micro Aerial Vehicle

Conceptual Design of a Micro Aerial Vehicle

... managerial effectiveness and a positive organizational ...managerial effectiveness in behavioral terms which evaluated managers on selected job oriented criteria such as communication, cost awareness, ...

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