comparative genomic hybridization array
Prenatal diagnosis of Wolf-Hirschhorn syndrome confirmed by comparative genomic hybridization array: report of two cases and review of the literature
... resolution array (kit 44 K) in case 1 and a 40 kb resolu- tion (kit 180 K) in case ...oligonucleotide array-CGH plat- forms (Agilent Technologies, Santa Clara, CA) as described elsewhere ...
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Chromosomal Aberrations in ETV6/RUNX1-positive Childhood Acute Lymphoblastic Leukemia using 244K Oligonucleotide Array Comparative Genomic Hybridization
... 244K array-based Comparative Genomic Hybridization (array-CGH) was used to study eleven ETV6/RUNX1-positive childhood acute lymphoblastic leukemia (ALL) ...the array findings, ...
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Prenatal diagnosis of 1p34.3 interstitial microdeletion by aCGH in a fetus with jaw bone abnormalities
... Array-based comparative genomic hybridization (array CGH) is a powerful method that allows the detection of submicroscopic alterations in human genome and thus identifies underlying ...
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Array-CGH characterization and genotype-phenotype analysis in a patient with a ring chromosome 6
... Array-Comparative Genomic Hybridization (Array-CGH) The array-Comparative Genomic Hybridization (aCGH) study was performed using the Agilent Human Genome CGH ...
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Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix
... and array-comparative genomic hybridization (array-CGH) and found that CIN genomes harbored fewer mutations (especially fewer driver mutations) and copy number alterations (CNAs), ...
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Application of Array Based Comparative Genomic Hybridization to Pediatric Neurologic Diseases
... Purpose: Array comparative genomic hybridization (array-CGH) is a technique used to analyze quantitative increase or decrease of chromosomes by competitive DNA hybridization of ...
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Prenatal diagnosis of a de novo interstitial deletion of 11q (11q22.3 → q23.3) associated with abnormal ultrasound findings by array comparative genomic hybridization
... [2]. Array comparative gen- omic hybridization (array CGH) has been introduced in prenatal diagnosis to rapidly detect genomewide gains and losses with higher resolution ...Kb. Array ...
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Submicroscopic copy-number variations associated with 46,XY disorders of sex development
... including array-based comparative genomic hybridization (aCGH), multiplex ligation-dependent probe amplification (MLPA), and next-generation sequencing (NGS), have enabled high-throughput ...
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Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridization
... Rectal cancer is the 5th leading cause of cancer-related death and its incidence is increasing at a rate of 4.2% per year in China [1]. Early detection and early therapy are important for the control of death caused by ...
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Array CGH and breast cancer
... chromosomes 3 and 5 and 10, which are more frequent then aberrations at the BRCA1 locus itself [56]. Thus, CGH has helped to uncover some of the intrinsic complexity of tumour chromosome behaviour, which is still poorly ...
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A 18p11.23-p11.31 microduplication in a boy with psychomotor delay, cerebellar vermis hypoplasia, chorioretinal coloboma, deafness and GH deficiency
... through array comparative genomic hybridization (aCGH), not overlapping with the previously described one, encompassing three genes, namely ARHGAP28 , LINC00668 and LAMA1 in a 10 year-old boy ...
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A microdeletion in the GRHL2 Gene in two unrelated patients with congenital fibrosis of the extra ocular muscles
... high-resolution array comparative genomic hybridization (arrayCGH) has the ability to detect small and potentially sympto- matic CNVs into the range of 1 ...
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Yield of comparative genomic hybridization microarray in pediatric neurology practice
... Only one other group based in Melbourne, Australia, have investigated the diagnostic yield of aCGH in a broad cohort of children seen in the pediatric neurology setting, similar to this study. 31 Their sample size of 215 ...
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Array-based comparative genomic hybridization for genomic-wide screening of DNA copy number alterations in aggressive bone tumors
... microarray hybridization buffer containing 50% forma- mide. The hybridization solution was heated to 80°C for 10 min to denature the DNA, and then was incubated for 1 h at ...37°C. Hybridization was ...
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13q mosaic deletion including RB1 associated to mild phenotype and no cancer outcome – case report and review of the literature
... hands). Array Comparative Genomic Hybridization on blood identified a mosaic ...Situ Hybridization (iFISH) on both blood genomic DNA and cultured/uncultured blood lymphocytes, ...
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Genetic analysis of products of conception using a HLPA/SNP-array strategy
... cludes array-based comparative genomic hybridization (aCGH) and single nucleotide polymorphism array (SNP- array) , and it is considered to be the fist-tier testing for detection ...
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Copy number variants in a sample of patients with psychotic disorders: is standard screening relevant for actual clinical practice?
... genome-wide array comparative genomic hybridization, studies on the putative genetic etiology of schizophrenia have focused on the detection of copy number variants (CNVs), ie, microdeletions ...
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Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: a case report and literature review
... our array comparative genomic hybridization (aCGH), fluorescence in situ hybridization (FISH) findings, and a missense mutation of TP53 gene by DNA sequencing in a 19-year-old patient ...
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Genomic profiling using array comparative genomic hybridization define distinct subtypes of diffuse large b-cell lymphoma: a review of the literature
... band region 9p24.1 in PMBL cell lines [40], and similar studies reported amplifications to 9p and 2p involving the REL locus on PMBL [21,40-42]. In 2007, Wessendorf et al. [43] further outlined chromosomal aberrations in ...
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Array Comparative Genomic Hybridization as a Diagnostic Tool in Cancer
... The array CGH, which is a combination of microarrays and CGH enables detection of smaller abnormali- ties, depending each time on the probes that are used ...field, genomic aberrations might contribute to ...
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