Complement Activation
Complement activation in the injured central nervous system: another dual-edged sword?
... the complement activation repertoire so that healthy host tissue is discri- minated and self-harm is ...between activation and regulation can induce self-attack, and excessive or inappropriate ...
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Complement activation in Ghanaian children with severe Plasmodium falciparum malaria
... to complement activation during severe malaria infection, there is an imbalance between pro- and anti-inflammatory ...measuring complement activation in children with acute malaria and may be ...
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Original Article Complement activation in the arteries of patients with severe atherosclerosis
... The complement system is widely recognized as a critical arsenal for immune surveillance and hemostasis in that it functions to eliminate invading pathogens and cell debris and to orchestrate immune ...of ...
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Metabolism of the fifth component of complement, and its relation to metabolism of the third component, in patients with complement activation
... parameters between patients with different types of complement activation. In patients with systemic lupus erythematosus, fractional catabolism and extravascular distribution of C3 and C5 were both ...
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Complement activation in multiple sclerosis plaques: an immunohistochemical analysis
... of complement immunolabelling in MS ...of complement staining in MS lesions was described by Lucchinetti and col- leagues; they proposed four distinct patterns of MS le- sions with only 50% of patients ...
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Involvement of Antilipoarabinomannan Antibodies in Classical Complement Activation in Tuberculosis
... Complement activation by rabbit anti-LAM Ab and ...classical complement activation induced by BCG, and (iii) rabbit Ab to LAM bound ...
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Adenovirus Activates Complement by Distinctly Different Mechanisms In Vitro and In Vivo: Indirect Complement Activation by Virions In Vivo
... activate complement in vitro, but activation of complement after Ad injection in vivo has not been directly ...Using complement protein C3a as a marker of comple- ment activation, we ...
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Complement activation at the motor end-plates in amyotrophic lateral sclerosis
... A role for MAC in the pathology of neurological disor- ders is suggested, including ALS [31]. In serum of ALS patients, the terminal complement activation products C5a and MAC are elevated [46]. MAC can ...
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Targeted and restricted complement activation on acrosome reacted spermatozoa
... the complement regulator membrane cofactor protein (MCP; CD46) is expressed on the inner acrosomal membrane (IAM) of ...the complement cascade efficiently through C3 but not ...and complement ...
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Cardiopulmonary and hemodynamic changes in complement activation related pseudoallergy
... Complement Activation-Related Pseudoallergy (CARPA) is a detrimental reaction of the cardiopulmonary system propelled by the hypersensitive reaction of the immune system in response to various C activating ...
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Complement activation products in the circulation and urine of primary membranous nephropathy
... of complement activation in pMN, there might be other participants other than MBL of activating MASP and C4 ...activate complement in patients with rheuma- toid arthritis by binding to IgG Fc that is ...
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Detection of complement activation using monoclonal antibodies against C3d
... During complement activation the C3 protein is cleaved, and C3 activation fragments are covalently fixed to ...C3 activation fragments when injected ...monitoring complement ...
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Murine Gammaherpesvirus 68 Encodes a Functional Regulator of Complement Activation
... Sequence analysis. The ␥HV68 genome sequence and putative ORFs were analyzed on Vector NTI version 4.0 Deluxe (Informax Inc., Gaithersburg, Md.) as previously described (65). The first 275 amino acids of the putative RCA ...
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Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study
... of complement activa- tion on Lewy bodies in melanized neurons in the PD sub- stantia nigra, and indicates that this process also occurs on some non-Lewy body-bearing melanized neurons and on melanin fragments in ...
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Role of Complement Activation in a Model of Adult Respiratory Distress Syndrome
... attendant complement activation on the sequestration of microorganisms and the leakage of albumin in the lungs of guinea ...pigs, complement-depleted guinea pigs did not localize injected bacteria to ...
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Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion
... in complement activation, but the kidney is unique in that activation after I/R occurs only via the alternative ...selective activation of this pathway after renal I/R could occur either ...
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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
... of complement in SARS-CoV infection has not yet been evaluated in ...the complement pathway as a high-priority target for control of SARS-CoV MA15 (the mouse-adapted SARS-CoV) pathogenesis based on weighted ...
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Plaque complement activation and cognitive loss in Alzheimer's disease
... Neuronal complement staining was present in many of the specimens in this study, but there were no differences between groups for this immunoreactivity and it was poorly correlated with cognitive ...indicates ...
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Cartilage oligomeric matrix protein induced complement activation in systemic sclerosis
... for complement activation [26], is engaged in multiple interactions in tissues, it is also possible that COMP needs to detach from its interacting partners in the tissue for it to be able to stimulate ...
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Complement Activation in Patients With Diabetic Nephropathy
... of complement activation in ...of complement in the development of DM-related complications, including DN, are ...whether complement activation occurred in renal autopsy samples ...
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