COMT val158met
Association of the COMT val158met variant with antidepressant treatment response in major depression
... the COMT 158val/val genotype with poor outcome after 5–6 weeks of treatment was slightly more pronounced in the female ...the COMT val158met polymorphism preferably in female patients (Alsobrook et ...
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Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults
... in COMT (G-to-A base-pair substitution) leading to a methi- onine (Met) valine (Val) substitution at codons 108/158 (COMT ...of COMT genotypes on the hypothetical inverted U-shaped curve has been ...
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Original Article COMT Val158Met polymorphism is associated with blood pressure and lipid levels in general families of Bama longevous area in China
... carried COMT 158Met present- ed lowered LDL-C level ...harbored COMT 158Met documented an elevated TG and homocysteine (Hcy) level in females but not in males ...between COMT 158Met and MTHFR 677C/T, ...
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Association between the COMT Val158Met polymorphism and risk of cancer: evidence from 99 case–control studies
... ORs and their 95% CIs were used to determine the strength of association between the COMT Val158Met polymorphism and cancer risk. The significance of the pooled OR was determined using the Z test, and ...
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Relationship between the COMT Val158Met and BDNF Val66Met Polymorphisms, Childhood Trauma and Psychotic Experiences in an Adolescent General Population Sample
... Briefly, the ABD study took place in counties Dublin and Kildare, Ireland, which contains a mixture of urban and suburban housing types of different socioeconomic status. Out of twenty seven schools approached, sixteen ...
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Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis
... with COMT Val158Met polymorphism and BC risk, which greatly increased statistical power of the analysis and provided enough evidence for us to draw a safe conclu- ...
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Association between the Catechol O Methyltransferase (COMT) Val158Met Polymorphism and Alexithymia in Patients with Obsessive Compulsive Disorder
... As COMT is a critical determinant of prefrontal DA flux, our results showing higher alexithymia in patients with the Val/Val genotype (higher COMT activity) suggest that lower DA levels in the prefrontal ...
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Caudate Volume in Offspring at Ultra High Risk for Alcohol Dependence: COMT Val158Met, DRD2, Externalizing Disorders, and Working Memory*
... Background: There is emerging evidence that the increased susceptibility to developing alcohol and substance use dis- orders in those with a family history of Alcohol Dependence (AD) may be related to structural ...
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The COMT Val158Met polymorphism does not modulate the after-effect of tDCS on working memory
... the COMT Val 158 Met polymorphism (rs4680) modulates the after- effect of prefrontal tDCS on verbal working memory ...the COMT Val 158 Met poly- morphism and received anodal- over- left, cathodal- over- ...
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No association between COMT val158met polymorphism and suicidal behavior: meta analysis and new data
... of COMT has been associated with a number of disorders including schizo- phrenia [19], bipolar disorder [20], major depressive dis- order [21], obsessive compulsive disorder [22], and Parkinson ’ s disease ...of ...
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Schizophrenia: genetics, prevention and rehabilitation
... of Val158Met polymorphism within the COMT gene (COMT Val158Met): high activity Val- allele, that is at risk for schizophrenia, modultes working memory and prefron- tal cortex function in both ...
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COMT genotype and non recovery after a whiplash injury in a Northern European population
... The COMT gene regulates formation of both soluble and membrane-bound protein ...The COMT Val158Met SNP, rs4680, is the most frequently investigated variant ...the COMT enzyme activity and has ...
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<p>Association between COMT polymorphism, labor anxiety, and analgesia in pregnant women</p>
... group. COMT, as the main enzyme degrading cat- echolamines, regulates the amount of catecholamines (and enkephalin) in vivo, including dopamine, norepinephrine, and ...the COMT Val158Met muta- tion ...
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<em>COMT </em>Val158Met, but not <em>BDNF </em>Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study
... the COMT Val158Met poly- morphism were determined in both the MDD patients and the control subjects, as shown in Table ...the COMT Val/Val group and the COMT ...
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No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol O methyltransferase gene The HUNT study
... In total 629 (45.7%) out of 1375 men and 900 (54.8%) out of 1642 women reported chronic MSCs. The distribu- tion of the COMT Val158Met genotypes and alleles were similar between controls and the twelve ...
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Catechol-O-Methyltransferase (COMT) Gene (Val158Met) and Brain-Derived Neurotropic Factor (BDNF) (Val66Met) Genes Polymorphism in Schizophrenia: A Case-Control Study
... between COMT Val158Met (G>A) and SCZ, while the BDNF Val66Met (G>A) variant was associated with the risk of SCZ, either genotype or ...in COMT Val158Met (G>A) and BDNF Val66Met ...
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Association between Catechol-O-methyltransferase rs4680 (G > A) polymorphism and lung cancer risk
... study by Cote et al. [18] reported the genotype frequency of both Africans and Caucasians; thus the data were collected separately based on ethnicities and considered as two studies. Therefore, five publications ...
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Association between <em>COMT</em> Val158Met and <em>DAT1</em> polymorphisms and depressive symptoms in the obese population
... and COMT genes, which are involved in dopaminergic neurotransmission, were associated with a higher intensity of depressive symptoms in obese ...the COMT Met allele manifested more severe depressive ...
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Lack of association between COMT gene polymorphism and treatment outcome in major depression
... membrane-bound COMT that corresponds to codon 108 of cytoplasmic COMT ...The COMT gene is located on the human chromosome 22 (12,13) and there is evidence from linkage studies for a susceptibility ...
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Study of traits and recalcitrance reduction of field-grown COMT down-regulated switchgrass
... Additional file 1. Supporting figures and tables of understanding the reduced cell wall recalcitrance of field‑grown COMT Down‑regulated switchgrass. Figure S1. Scheme of proposed lignin biosynthesis involv‑ ing ...
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