Conserved residues
Identification and localization of Tospovirus genus wide conserved residues in 3D models of the nucleocapsid and the silencing suppressor proteins
... various conserved residues should be discerned to determine the stability of the protein and the possible residues involved in the functions of the protein either in silico or in vitro ...these ...
15
Identification of Conserved Residues Contributing to the Activities of Adenovirus DNA Polymerase
... these residues are required for efficient interaction of Adpol with ...the residues required for DNA binding of Adpol are clustered in the C-terminal region of the protein and are lo- cated both within ...
9
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
... the conserved sites within the putative CD81 binding regions ...the conserved cysteine residues were not ...these residues form part of the AP33 epitope ...acids conserved in functional ...
10
Conserved Residues in Ycf54 are required for Protochlorophyllide Formation in Synechocystis sp. PCC 6803.
... HNCI/[eh76"cpf"HNCI/C;I0"Kpfggf."rtgxkqwu"rwnnfqyp"gzrgtkogpvu"*3;+"ujqygf"vjcv"qpn{"HNCI/ [eh76"nqecvgf"ykvjkp"vjg"kpuqnwdng"htcevkqp"ycu"ecrcdng"qh"kpvgtcevkpi"ykvj"E{eK"cpf"cpcn{ugu"q[r] ...
32
Genetic analysis of the activation domain of bovine papillomavirus protein E2: its role in transcription and replication.
... is conserved between many strains of papillomavirus. We targeted conserved residues spanning the activation domain and constructed a series of 30 amino acid substitution ...
7
PubMedCentral-PMC5584451.pdf
... NOD-like receptor (NLR) family to recognize the presence of pathogen- derived effector proteins. NLRs possess an N-terminal Toll-like/IL-1 receptor (TIR) or a non-TIR domain [some of which contain coiled coils (CCs)], a ...
10
Isolation and Characterization of the Herpes Simplex Virus 1 Terminase Complex
... these conserved residues within the UL15 ho- molog in HCMV, UL89, disrupted the nuclease activity displayed by a purified C-terminal fragment of the UL89 protein ...
12
Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14 alpha-demethylase
... highly conserved residues, particularly at the azole binding site, and heterologous expression of LmCYP51B and LbCYP51B, with fungicide sensitivity testing of the transformants, suggests that both proteins ...
13
Using Evolutionary Rates to Investigate Protein Functional Divergence and Conservation: A Case Study of the Carbonic Anhydrases
... The conserved or nearly conserved residues method has not yet been studied with real or simulated of CA III at these rate change sites may contribute to data nor is it currently implemented in a ...
10
Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase
... only residues that are highly conserved in the SAM-binding region of the core fold are the glycine-rich sequence E/DxGxGxG (often referred to as motif I) between  1 and ␣ A, which interacts with the amino ...
10
Importance of Conserved Cysteine Residues in the Coronavirus Envelope Protein
... have conserved cysteine residues located on the carboxy side of the long hydrophobic domain, suggesting functional ...the conserved residues and the necessity of palmitoylation, three ...
11
Determinants of Dengue Virus NS4A Protein Oligomerization
... flavivirus conserved NS4A amino ...fully conserved residues, whereas the colons and periods mark strongly and weakly similar residues, ...of conserved residues selected for ...
13
Structure Function Analysis of Diacylglycerol Acyltransferase Sequences from 70 Organisms
... acid residues are completely con- served, which correspond to ...completely conserved residues in DGAT1s from repre- sentatives of animal group (mouse), plant group (tung tree) and fungus group ...
24
Bayesian classification of residues associated with protein functional divergence: Arf and Arf-like GTPases
... co- conserved residues and instead are associated with a different set of co-conserved residues: two aromatic resi- dues (Phe91 Rab11 and Trp105 Rab11 in ...buried conserved water ...
17
Page_unc_0153D_15827.pdf
... five conserved active site residues that are critical for receiver domain function (23) were then ...Glu residues), "D" (Asp only), "T" (Ser or Thr), and "K" (Lys only) with ...
127
Role of Helix P of the Human Cytomegalovirus DNA Polymerase in Resistance and Hypersusceptibility to the Antiviral Drug Foscarnet
... of conserved domain III of the HCMV DNA polymerase ...are residues that have been associated with changes in drug susceptibility: cidofovir (CDV), ganciclovir (GCV), and foscarnet ...acid residues ...
11
Dissection of Functional Sites in Herpesvirus Saimiri Complement Control Protein Homolog
... Herpesvirus saimiri is known to encode a homolog of human complement regulators named complement control protein ho- molog (CCPH). We have previously reported that this virally encoded inhibitor effectively inactivates ...
15
Session 4: Peptide transport
... Results and conclusions from these experiments suggested that the carboxyl group at Glu388 can sense the change in N-terminal position and hence acts as a counter-ion to the peptide N-terminal positive charge. ...
5
Mutations in the Stalk of the Measles Virus Hemagglutinin Protein Decrease Fusion but Do Not Interfere with Virus-Specific Interaction with the Homologous Fusion Protein
... heptadic residues, was also ...remaining residues, F96 and K97, result in signifi- cant deficiencies in fusion promotion not attributable to cor- responding reductions in receptor ...the conserved ...
11
Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala
... In this study, a distinctive putative OPH (AbOPH) identified from Acinetobacter sp. exhibited high lactonase activity with latent OPH activity. Compared with OPHC2 and MPH in β -lactamase superfamily, AbOPH acts as a ...
8