Cortical bone response to mechanical loading
Effects of eldecalcitol on cortical bone response to mechanical loading in rats
... “bouton-like” bone formation patterns characteristic of bone minimodeling in eldecalcitol-treated ovariecto- mized rats at rates 10-fold higher than in those treated with calcitriol, and suggested that ...
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Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response
... osteogenic response to mechanical loading 28 ...external loading to murine tibia in pre- vious studies have established that loads of 11–13 N applied to mouse tibiae at a range of ages, up to ...
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Variation in estradiol level affects cortical bone growth in response to mechanical loading in sheep
... more bone growth than those with normal E 2 levels, is strongly supported in the femur, in which HE animals had 16–92% more bone growth than any other treatment ...on bone growth remain ...
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Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading
... to mechanical stimuli may underpin the decline in aged bone’s fracture ...osteogenic response, and respond less exuberantly to loading than young adults 2,4,7,17 ...to loading in aged bones ...
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Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones
... to mechanical loading is a local phenomenon, we randomly assigned 21 female C57BL/6 mice at 19 weeks of age to one of three equal numbered ...percent bone volume and cortical bone ...
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Predicting cortical bone adaptation to axial loading in the mouse tibia
... mechanical loading as the major contributor for the adaptive response observed in the loaded ...of cortical thickness changes allowed for a comprehensive method for comparison of in vivo and ...
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Mechanical Loading Attenuates Radiation-Induced Bone Loss in Bone Marrow Transplanted Mice
... of bone to ionizing radiation, as occurs during radiotherapy for some localized malignancies and blood or bone marrow cancers, as well as during space travel, incites dose-dependent bone morbidity ...
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Optimization of bone growth and remodeling in response to loading in tapered mammalian limbs
... to mechanical loading through changes in shape and structure is poorly understood, particularly with respect to variations between ...Structurally, cortical bones adapt in vivo to their ...
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The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading
... mechanical loading induced an osteogenic response in both strains of mice in terms of increased 47.. total bone volume and cortical bone volume, with the P2Y 13 R -/- mice h[r] ...
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Maternal pregnancy vitamin D supplementation increases offspring bone formation in response to mechanical loading : findings from a MAVIDOS trial sub-study
... to mechanical stimulation with an increase in bone size and mass and that can persist into adult life 13,14 ...without mechanical stimulation, peak bone mass may not be fully achieved 15,16 ...
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Fracture characterization of human cortical bone under mode II loading using the end-notched flexure test
... B = 2.5 (units: mm). Specimens were continuously irri- gated with physiological saline at all steps of the machin- ing process and then frozen at −20 °C for storage before testing. The initial crack length a 0 was ...
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Spatial relationship between bone formation and mechanical stimulus within cortical bone: Combining 3D fluorochrome mapping and poroelastic finite element modelling
... the bone mechano-adaptative response on the entire cortex by directly visualizing the locations of bone formation in a murine tibia loading model using 3D fluorochrome ...of bone ...
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Spatial relationship between bone formation and mechanical stimulus within cortical bone: Combining 3D fluorochrome mapping and poroelastic finite element modelling
... T Bone is a dynamic tissue and adapts its architecture in response to biological and mechanical ...how cortical bone formation is spatially controlled by the local mechanical ...
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Loading conditions and cortical bone construction of an artiodactyl calcaneus
... Pilot studies showed that reaction forces at the hoof were not predominantly in the vertical direction, which this study had intended to simulate, but had a notable horizontal component. In addition, upon loading ...
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The response of anosteocytic bone to controlled loading
... of loading on mammalian bones is often performed by applying load to one limb and considering the difference from the unloaded limb, which serves as an unaffected control (Forwood et ...accelerated bone ...
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Knee loading stimulates cortical bone formation in murine femurs
... elbow loading to knee loading and examines the anabolic effects on femoral cortical ...knee loading stimulates bone formation in the tibia [12,13], but no study has been performed to ...
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Multiscale characterization of mechanical and fracture properties of cortical bone specimens
... the bone can be further divided into various components as shown in Figure ...of bone and is the location which consists of ...the cortical bone which extend along the longitudinal axis of the ...
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Effect of micromorphology of cortical bone tissue on crack propagation under dynamic loading
... Introduction Bone has a highly heterogeneous structure at a micro- scale level, consisting of Haversian canals, osteons, cement lines and an interstitial ...degenerative bone diseases can increase the risk ...
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Influence of strain rate on the mechanical behaviour in tension of bovine cortical bone
... The mechanical behaviour of bones when subjected to tension loading in a wide range of strain-rates is fundamental to develop protection ...bovine cortical bone at medium and high strain ...
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Wave response of the solids by mechanical loading: overall model
... A particular emphasis is placed herein on the role of the phonon subsystem in the evolution of localized plastic deformation, which involves (i) relaxation acts due to the motion of di[r] ...
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